Results 31 to 40 of about 21,705 (315)
Pediatric Blood &Cancer, EarlyView.ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider +4 more
wiley +1 more source
Intramedullary nailing of adult femoral fractures
Acta Orthopaedica et Traumatologica Turcica, 2021 Objectives: We evaluated the results of treatment of adult femoral fractures treated by intramedullary nails.\nMethods: Sixty-two patients (15 females, 48 males; mean age 29 years; range 16 to 62 years) with 64 femoral fractures were treated by ...
Oguz Durakbasa +3 more
doaj
Extra Articular Supracondylar Femur Fractures Managed with Locked Distal Femoral Plate or Supracondylar Nailing: A Comparative Outcome Study [PDF]
Journal of Clinical and Diagnostic Research, 2017 Introduction: Despite recent evolution in the operating techniques and surgical implants, debate continues around the choice of implant for management of distal femur fractures.
SPS Gill +5 more
doaj +1 more source
Comparison of carbon fibre and titanium intramedullary nails in orthopaedic oncology
Bone & Joint Open, 2022 Aims Due to their radiolucency and favourable mechanical properties, carbon fibre nails may be a preferable alternative to titanium nails for oncology patients.
Caleb M. Yeung +6 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Acta Orthopaedica et Traumatologica Turcica, 2021 Objectives: To evaluate long-term results of surgical treatment of fractures of the lateral humeral condyle in children.\nMethods: We evaluated 62 children (mean age 6.9 years) who underwent open reduction and osteosynthesis with Kirschner wires for ...
Metin Kucukkaya +3 more
doaj
FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
Treatment of femoral shaft fractures by interlocking intramedullary nailing in adults
Acta Orthopaedica et Traumatologica Turcica, 2021 Objectives: We evaluated the radiological, clinical, and functional results of femoral shaft fractures treated by interlocking intramedullary nailing.\nMethods: Interlocking intramedullary nailing was performed in 48 femoral shaft fractures of 46 ...
M. Omer Arpacioglu +4 more
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