Results 41 to 50 of about 2,891,223 (328)

Lengthening Nails for Distraction Osteogenesis: A Review of Current Practice and Presentation of Extended Indications

open access: yesStrategies in Trauma and Limb Reconstruction, 2020
Purpose Circular frames have been the gold standard of treatment for complex deformity corrections and bone loss. However, despite the success of frames, patient satisfaction has been low, and complications are frequent.
A. Barakat   +3 more
semanticscholar   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

The Possibility of Interlocking Nail Fabrication from FFF 3D Printing PLA/PCL/HA Composites Coated by Local Silk Fibroin for Canine Bone Fracture Treatment

open access: yesMaterials, 2020
The biomaterials polylactic acid (PLA), polycaprolactone (PCL), and hydroxyapatite (HA) were selected to fabricate composite filaments for 3D printing fused filament fabrication (FFF), which was used to fabricate a composite biomaterial for an ...
S. Pitjamit   +5 more
semanticscholar   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Surgical management of displaced fractures of the lateral humeral condyle in children: results of eightyear followup

open access: yesActa Orthopaedica et Traumatologica Turcica, 2021
Objectives: To evaluate long-term results of surgical treatment of fractures of the lateral humeral condyle in children.\nMethods: We evaluated 62 children (mean age 6.9 years) who underwent open reduction and osteosynthesis with Kirschner wires for ...
Metin Kucukkaya   +3 more
doaj  

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Treatment of femoral shaft fractures by interlocking intramedullary nailing in adults

open access: yesActa Orthopaedica et Traumatologica Turcica, 2021
Objectives: We evaluated the radiological, clinical, and functional results of femoral shaft fractures treated by interlocking intramedullary nailing.\nMethods: Interlocking intramedullary nailing was performed in 48 femoral shaft fractures of 46 ...
M. Omer Arpacioglu   +4 more
doaj  

Extra Articular Supracondylar Femur Fractures Managed with Locked Distal Femoral Plate or Supracondylar Nailing: A Comparative Outcome Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2017
Introduction: Despite recent evolution in the operating techniques and surgical implants, debate continues around the choice of implant for management of distal femur fractures.
SPS Gill   +5 more
doaj   +1 more source

Use of a Magnetic Bone Nail for Lengthening of the Femur and Tibia [PDF]

open access: yesJournal of Orthopaedic Surgery, 2016
Purpose To report our experience with the PRECICE nail for limb lengthening in 23 patients. Methods Records of 15 female and 8 male patients aged 14 to 38 (mean, 23.6) years who underwent lengthening of the tibia (n=6) or femur (n=21 ...
Karakoyun, Özgür   +4 more
openaire   +4 more sources

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

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