Immunohistochemical evaluation of T cell receptor and T cell receptor beta constant 1 expression distinguishes benign and neoplastic immature T-cell populations and reveals discrete TRBC1/TCR phenotypes. [PDF]
Chaudhary S +4 more
europepmc +1 more source
Mechanobiological Dynamics‐Inspired Mechanomodulatory Biomaterials
Recent advances in biomaterial‐mediated mechanomodulation of stem cell fate, encompassing 2, 3, and 4D systems and their synergy with artificial intelligence is overviewed. By integrating knowledge from diverse fields, this review ultimately aims to inspire the design of smarter biomaterial systems that can accelerate the clinical translation of ...
Letao Yang +6 more
wiley +1 more source
Uncommon Bedfellows: Coexistent T-Cell Large Granular Lymphocytic Leukaemia and Hodgkin Lymphoma-A Case Report. [PDF]
van Tonder D, Roets B, Holland N.
europepmc +1 more source
The Pathogenic Roles of Local Vitamin D Metabolism Defect in Valve Inflammation and Calcification
This study identifies the valvular interstitial cell populations responsible for valvular calcification induced by hyperphosphatemia and likely aging, uncovers local vitamin D metabolism defect‐induced inflammation as a critical pathogenic factor of calcific aortic valve disease, and highlights active vitamin D and ERK inhibitor as potential preventive
Ruichen Yang +10 more
wiley +1 more source
Bone marrow mastocytosis associated with primary cutaneous follicle center lymphoma: an unusual case report. [PDF]
John MV +8 more
europepmc +1 more source
Cancer Immunotherapy via Disruption of Integrin αvβ3 and CD47 Costabilization on Cancer Cell Surface
This study identifies a cancer‐specific interaction between CD47 and integrin αvβ3 that facilitates immune evasion. A rationally designed peptide, PSFL‐NK13, disrupts this axis, enhancing macrophage‐mediated phagocytosis and suppressing tumor growth without inducing anemia.
Peng‐Cheng Yu +12 more
wiley +1 more source
Occult Breast Cancer Diagnosed from a Solitary Scalp Metastasis without Axillary Lymph Node Involvement: A Case Report. [PDF]
Ushio T +7 more
europepmc +1 more source
Calhm6 drives M2 macrophage polarization via the Chp1‐Camk4‐Creb1 axis, suppressing inflammation through calcium‐dependent ectosomal delivery. Calhm6 deficiency enhances M1 responses, boosting bactericidal activity but exacerbating tissue damage. LPS/IFNγ upregulate Calhm6 via Irf1, while IL‐4/Stat6 inhibits it, balancing immune outcomes.
Yanlong Xin +14 more
wiley +1 more source
A case report: pediatric rhabdomyosarcoma presenting with bone marrow metastasis. [PDF]
Xiong T +6 more
europepmc +1 more source

