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Bone morbidity in chronic myeloproliferative neoplasms
Expert Review of Hematology, 2015Patients with the classical Philadelphia chromosome-negative chronic myeloproliferative neoplasms including essential thrombocythemia, polycythemia vera and primary myelofibrosis often suffer from comorbidities, in particular, cardiovascular diseases and thrombotic events.
Farmer, Sarah +5 more
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Conditions Simulating Primary Bone Neoplasms
Surgical Pathology Clinics, 2017A number of nonneoplastic conditions can mimic tumors of bone. Some of the more common mimics of primary bone tumors include infectious, inflammatory, periosteal, and degenerative joint disease-associated lesions that produce tumorlike bone surface-based or intraosseous lesions.
Benjamin M. Howe +2 more
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Mimics of Bone and Soft Tissue Neoplasms
Radiologic Clinics of North America, 2011Many benign nonneoplastic entities can mimic bone and soft tissue tumors on imaging examinations. Distinguishing between neoplastic and nonneoplastic entities depends on history and physical examination findings and imaging findings, and is an important early step in the patient's overall workup and treatment plan.
G. Scott Stacy, Avnit Kapur
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Breast neoplasms containing bone and cartilage
Virchows Archiv A Pathological Anatomy and Histopathology, 1983A total of 307 breast neoplasms and tumour-like conditions were reviewed to assess the frequency with which bone and/or cartilage occurred. Of 90 fibroadenomas, 1 (1.1%) and 2 of 158 breast carcinomas (1.3%) contained bone, one benign mesenchymoma contained cartilage, and one benign "mixed" tumour (pleomorphic adenoma) displayed cartilage and bone ...
D. V. Spagnolo, K. B. Shilkin
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Reactive bone lesions mimicking neoplasms
Seminars in Diagnostic Pathology, 2011Reactive lesions of bone and soft tissue can appear alarming on histologic examination because they are often cellular and have atypical (activated) cytologic features, such as distinct nucleoli and mild hyperchromasia, and mitotic activity. Reactive lesions of bone and periosteum also produce bone and cartilage matrix, resulting in confusion with ...
Benjamin Hoch, Anthony G. Montag
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Pathology of pleomorphic/undifferentiated and dedifferentiated bone neoplasms
Seminars in Diagnostic Pathology, 2021Primary malignant bone tumors are uncommon and their accurate classification requires careful correlation of clinical, radiological, and pathologic findings. It is a heterogeneous group of tumors with a wide spectrum of morphology and their biological potential can be of low- or high-grade, depending on their risk for developing metastases.
Andrew E. Rosenberg, Iva Brcic
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Aspiration biopsy of primary neoplasms of bone.
The Journal of Bone & Joint Surgery, 1989Aspiration biopsy of bone is a simple and relatively safe diagnostic tool that had a diagnostic accuracy of 72 per cent in thirty-one patients who had a primary bone tumor that was suspected of being malignant and of 83 per cent in twelve patients who had a suspected giant-cell tumor. However, twenty-six primary lesions of bone that were thought likely
P G Carnesale +3 more
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Extradural Petrous Bone and Petroclival Neoplasms
1991Extradural petroclival tumours are composed of a spectrum of histological and anatomical configurations dictating a variety of surgical approaches. The experience with 68 such tumours operated at the University of Pittsburgh is presented, emphasizing the basal subfrontal and lateral approaches. 85% of these tumours are benign or low-grade malignancies,
Sh. Pomeranz +2 more
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Soft Tissue and Bone Neoplasms
2018Bone and soft tissue tumors are overall rare but are histologically complex and biologically diverse. Recurring molecular events help define benign and malignant entities as well as confirm the neoplastic nature of lesions previously considered to represent reactive proliferations.
Peter Pytel, Nicole A. Cipriani
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1985
Malignancy of any type developing during pregnancy is uncommon and is estimated at approximately 1/1000 pregnancies.1 Similarly, primary bone sarcomas are uncommon. Osteosarcoma, the most frequent malignant bone neoplasm encountered in the childbearing years, occurs in only 1/100,000 population.2 The Third National Cancer Survey3 indicates that 27% of ...
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Malignancy of any type developing during pregnancy is uncommon and is estimated at approximately 1/1000 pregnancies.1 Similarly, primary bone sarcomas are uncommon. Osteosarcoma, the most frequent malignant bone neoplasm encountered in the childbearing years, occurs in only 1/100,000 population.2 The Third National Cancer Survey3 indicates that 27% of ...
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