Results 51 to 60 of about 974,457 (254)

Technique for Foot Reconstruction with Custom-made Calcaneal Prosthesis in Primary Malignancy - A Case Report

Revista Brasileira de Ortopedia, 2023
The foot is an uncommon location for osseous tumors, comprising ~ 3% of all skeletal tumors, which occur particularly around the calcaneum. Radical surgery creates a void in the foot which adversely affects the ability to salvage it.
Aditya K.S. Gowda, Mohit Dhingra, Madhubari Vathulya, Rajkumar K. Seenivasagam   +3 more
doaj   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Review of thirty patients with bone chondroblastoma [PDF]

Vojnosanitetski Pregled, 2005
Background/Aim. To analyse the results of the treatment of the patients with the diagnosis of chondroblastoma, to confirm the possible malignancy and to recommend the best and the safest method of the treatment. Methods.
Slavković Slobodan, Tomić Slavko, Slavković Nemanja, Apostolović Milan   +3 more
doaj   +1 more source

Upper Limb Muscle–Bone Asymmetries and Bone Adaptation in Elite Youth Tennis Players [PDF]

, 2013
Introduction: The study of tennis players allows the nonracket arm to act as an internal control for the exercising racket arm. In addition, the study of the upper limbs removes the influence of gravitational loading, allowing the examination of the ...
Degens H., Ireland A., Cooke, K, Maden-Wilkinson T., McPhee J., Degens, Hans, Maden-Wilkinson, Thomas, Rittweger J., Degens, H., Mcphee, J, Degens, H, Ireland, A., Narici, Marco, Ireland, Alex, McPhee, Jamie, Rittweger, J., Rittweger, Jörn, Ireland, A, Rittweger, J, Maden-Wilkinson, Tom, Narici, M, Narici, M., Cooke, Karl, Cooke, K., Maden-Wilkinson, T, Narici M., McPhee, J., Cooke K.   +27 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

RANKL/RANK/osteoprotegerin system as novel therapeutic target in the treatment of primary bone tumors and osteolytic metastases [PDF]

Archive of Oncology, 2004
Primary bone tumors and cancers that metastasize to bone require osteoclastic activity to release tumor-supportive growth factors from bone tissue.
Anđelković Zlatibor, Katić Vuka V., Mihailović Dragan S., Petrović Aleksandar S., Bubanović Ivan   +4 more
doaj   +1 more source

The role of peptides and receptors of the calcitonin family in the regulation of bone metabolism

, 2008
The ‘calcitonin family’ is a group of peptide hormones that share structural similarities with calcitonin, and includes calcitonin gene-related peptide (CGRP), amylin, adrenomedullin and adrenomedullin 2 (intermedin).
Naot, Dorit, Cornish, Jillian
core   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source