Results 71 to 80 of about 2,322,935 (342)

Isolated bone marrow gamma-delta T-Cell lymphoma: Another challenge to the WHO lymphoid neoplasm classification

, 2023
Rohit Singh, David Alejos, Casey Rankins, Katherine Devitt, Joanna L. Conant, Diego Adrianzen Herrera   +5 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Creutzfeldt-Jakob Disease as a Reason for Neurological Deterioration in a Patient with Acute Lymphoblastic Leukemia after Allogeneic Hematopoietic Stem Cell Transplantation

Turkish Journal of Hematology, 2023
Magdalena Karasek, Melissa Szmukala, Joanna Bladowska, Jakub Ubysz, Halina Bielecka, Marta Sobas   +5 more
doaj   +1 more source

Clinical characteristic-assisted surgical benefit stratification for resection of primary tumor in patients with advanced primary malignant bone neoplasms: a population-based propensity score-matched analysis. [PDF]

Front Oncol, 2023
Tong Y, Jiang L, Cui Y, Pi Y, Gong Y, Zhao D.   +5 more
europepmc   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Prevalence, Risk Factors, and Prognostic Factors of Primary Malignant Bone Neoplasms with Bone Metastasis at Initial Diagnosis: A Population-Based Study. [PDF]

J Oncol, 2022
Xiao ZW, Guo HL, Chen HC, Yan LP, Liao YL, Li SL, Zhao LL, Su LB, Li JJ, Tang FQ.   +9 more
europepmc   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Medication-related osteonecrosis of the jaw in a breast cancer patient receiving denosumab for bone metastases: a case report [PDF]

Kosin Medical Journal
The use of bone-modifying agents in cancer patients to prevent skeletal-related complications associated with bone metastases has been linked to an increased risk of medication-related osteonecrosis of the jaw (MRONJ).
Min-Kyeong Kim
doaj   +1 more source

The Associations between Racial Disparities, Health Insurance, and the Use of Amputation as Treatment for Malignant Primary Bone Neoplasms in the US: A Retrospective Analysis from 1998 to 2016. [PDF]

Int J Environ Res Public Health, 2022
Lapica H, Ozery M, Raju H, Castro G, Rodriguez de la Vega P, Barengo NC.   +5 more
europepmc   +1 more source

JAK2 p.V617F detection and allele burden measurement in peripheral blood and bone marrow aspirates in patients with myeloproliferative neoplasms [PDF]

, 2013
Koichi Takahashi, Keyur P. Patel, Hagop M. Kantarjian, Rajyalakshmi Luthra, Sherry Pierce, Jörge E. Cortes, Srđan Verstovšek   +6 more
openalex   +1 more source