Results 171 to 180 of about 209,372 (314)

Integration of Bone Remodeling and Damage Accumulation: A Preliminary Computational Framework for Physiological and Pathological Responses. [PDF]

Acta Biotheor
Garzón-Alvarado DA, Duque-Daza CA, Linero DL, Nedjar B, May A, Casas EBL, Ramtani S.   +6 more
europepmc   +1 more source

Sulfated galactofucan from Sargassum fusiforme protects against postmenopausal osteoporosis by regulating bone remodeling [PDF]

Bao Yizhong, Fen Chen, Weihua Jin, Jihua Dai, Genxiang Mao, Bo-Shan Song   +5 more
openalex   +1 more source

Macrophage‐to‐Myofibroblast Transdifferentiation Contributes to Pulmonary Fibrosis via the MERTK‐SPP1‐SRC‐TKS5 Signaling Axis

Advanced Science, EarlyView.
MERTK is upregulated in fibrotic macrophages and regulates the expression and activity of SRC and TKS5 through SPP1, mediating transdifferentiation of macrophages‐to‐myofibroblasts (MMT) and promoting pulmonary fibrosis. The figure was created with BioRender.com.
Yungeng Wei, Hua Guo, Xiangsheng Yang, Xiao Xiao Tang   +3 more
wiley   +1 more source

Plant Transformation States and Exposure Architecture: A Pharmacokinetic Framework for Plant-Derived Compounds in Bone Remodeling. [PDF]

Plants (Basel)
Khaleel S, Al-Qirim T, Alhusban AA, Aburjai T, El Khassawna T.   +4 more
europepmc   +1 more source

Orchestrated Engineered Polyphenol‐Peptide Condensates Coupled With β‐GP Reverses Diabetic Osteoporosis by Remodeling Mitophagy

Advanced Science, EarlyView.
A multifunctional β‐GP@EGCG‐E7 nanoplatform is engineered by polyphenol–peptide condensation and phosphate loading. Bone‐targeted delivery, antioxidant and anti‐inflammatory activity, and mitophagy restoration are integrated in one system, enabling protection of osteoblasts and endothelial cells and promoting bone regeneration under diabetic ...
Xiuyun Xu, Meiqin Zhang, Ting Wu, Erfan Wei, Andrei Y. Hancharou, Zeying Wang, Zijuan Wang, Letian Lv, Likun Wu, Xingtong Pan, Qiyue Zhu, Xinyi Dong, Hao Liu, Yongsheng Zhou   +13 more
wiley   +1 more source

Circulating Molecular Drivers of Bone Remodeling in Pancreatitis. [PDF]

Clin Transl Gastroenterol
Hill RL, Yadav D, Hart PA, Whitcomb DC, McQuerry KJ, Karnik KN, Stello KM, Conwell DL, Rao M.   +8 more
europepmc   +1 more source

Global deletion of Optineurin results in altered type I IFN signaling and abnormal bone remodeling in a model of Paget’s disease [PDF]

, 2019
Sing‐Wai Wong, Bowen Huang, Xiangxiang Hu, Eui Ho Kim, Joseph P. Kolb, Ricardo J. Padilla, Peng Xue, Lufei Wang, Thomas H. Oguin, Patrícia A. Miguez, Henry C. Tseng, Ching‐Chang Ko, Jennifer Martinez   +12 more
openalex   +1 more source

BCMA‐Engineered Dendritic Cell‐Derived Exosomes as Bi‐Functional Therapeutics Orchestrating Cytokine Sequestration and Immune Activation for Multiple Myeloma

Advanced Science, EarlyView.
A dual‐function cell‐free therapeutic based on DC2.4 cell‐derived exosomes engineered to display BCMA. (Left) Soluble Ligand Sequestration (Decoy Function): DB Exo act as molecular decoys that predominantly sequester soluble APRIL with partial BAFF attenuation, effectively disrupting the NF‐κB survival signaling axis and suppressing myeloma cell ...
Yuqing Zeng, Chao He, Zhibin He, Hongbo Chen, Fang Cheng, Yongjiang Zheng   +5 more
wiley   +1 more source

A 3‑Dimensional Scaffolding System Recapitulates the Hierarchical Osteon Structure

ACS Omega
Xiheng Li, Yalu Sun, Shuangshuang Wang, Chao Si, Huen Li, Bei Chang   +5 more
doaj   +1 more source

Talin1 loss activates DRG neurons to accelerate bone remodeling and fracture healing in mice. [PDF]

J Orthop Translat
Yan Q, Gan D, Xu K, Chen Z, Lin S, Zhou B, Xu Z, Zhong Q, Tao C, Zhong Y, Huo S, Yi W, Wang Z, Song X, Qin L, Xiao G.   +15 more
europepmc   +1 more source