Results 221 to 230 of about 209,372 (314)

A Periosteum‐Inspired Janus Piezoelectric Scaffold Using Bioenergetic‐Driven H‐Type Vascularization for Diabetic Bone Regeneration

open access: yesAdvanced Science, EarlyView.
A periosteum‐inspired Janus piezoelectric scaffold converts micromechanical forces into electrical signals and synergizes with controlled resveratrol release. This dual action reprograms endothelial metabolism, drives H‑type vessel formation, and restores bone–vessel coupling in diabetic bone defects.
Kai Wang, Kai Jiang
wiley   +1 more source

Uncoupled bone remodeling drives myeloma bone disease in Vk*MYC mouse model of multiple myeloma. [PDF]

open access: yesBone Rep
Schmal C   +9 more
europepmc   +1 more source

A Wireless 3D Magneto‐Mechanical Stimulation Platform Drives In Situ Chondrogenic Commitment of Endogenous MSCs

open access: yesAdvanced Science, EarlyView.
An intracellular magneto‐mechanical platform utilizing MSC‐targeted nanomotors is developed. After intra‐articular delivery, these nanomotors target endogenous BMSCs and are actuated within lysosomes to execute trans‐planar rotational‐bouncing motions under a rotating‐fluctuating 3D magnetic field, generating amplified mechanical stimulation.
Zhenguang Li   +7 more
wiley   +1 more source

Propranolol-loaded multifunctional hydrogel enhances the repair of infected bone defects via sympathetic microenvironment remodelling

open access: hybrid
Wenzhe Sun   +14 more
openalex   +1 more source

BC-JP-2 Bone Quality Evaluation Based on Bone Remodeling and Multi-scale Simulation

open access: diamond, 2012
Daisuke TAWARA   +3 more
openalex   +2 more sources

Cholesterol‐Mediated Metabolic‐mechanotransductive Crosstalk Orchestrates Castration Resistance in Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Full androgen deprivation (FAD) induces paracrine cholesterol in prostate cancer that drives the polarization of cancer‐associated fibroblasts (CAFs) and subsequent elevated matrix stiffness. Matrix stiffness in turn potentiates tumor cell survival under FAD pressure via dual mechanotransductive activation of the IRE1α‐XBP1s stress‐response axis ...
Shaojie Liu   +20 more
wiley   +1 more source

Bone remodeling, not inflammation, as the predominant pathology in modic type 1 lesions of the lumbar spine. [PDF]

open access: yesPain Med
Kreutzinger V   +7 more
europepmc   +1 more source

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