Results 251 to 260 of about 2,011,561 (382)
These findings reveal that silicon exerts strong protective effects in diabetic bone defect models by selectively promoting Drp1‐Mff activity. Silicon facilitates precise regulation of mitochondrial dynamics to enable functional mitochondrial transfer.
Yu‐Xuan Ma+12 more
wiley +1 more source
Phytol-mixed micelles alleviate dexamethasone-induced osteoporosis in zebrafish: Activation of the MMP3-OPN-MAPK pathway-mediating bone remodeling. [PDF]
Liu B, Wang P, Lv X.
europepmc +1 more source
A preliminary in vitro and in vivo study of the effects of new anthraquinones on neutrophils and bone remodeling [PDF]
L. Savarino+9 more
openalex +1 more source
Development of MDM2‐Targeting PROTAC for Advancing Bone Regeneration
This work presents a creative pipeline for developing MDM2‐targeting PROTACs (MDM2‐PROTACs) for application in bone regeneration. The developed PROTACs (CL144 and CL174) are validated for their degradation efficiency and osteogenic effects in human BMSCs.
Sol Jeong+17 more
wiley +1 more source
Molecular Signaling Pathways and MicroRNAs in Bone Remodeling: A Narrative Review. [PDF]
Singh M+6 more
europepmc +1 more source
IR783‐stabilized nanodrugs composed of NIR dye IR783, ROS inducer β‐lapachone, and epigenetic modulator CUDC101 are designed for breast cancer immunotherapy. The nanodrugs can not only promote cancer cell apoptosis through HDAC inhibition‐enhanced oxidation therapy but also reshape the immunosuppressive microenvironment, which provides a novel strategy
Jinzhao Liu+6 more
wiley +1 more source
The Evaluation of New-Generation Biomarker sCD14ST Provides New Insight into COVID-19's Effect on Bone Remodeling. [PDF]
Galliera E+6 more
europepmc +1 more source
MP3 tumor cells, a specific subpopulation of tumor cells in D‐TGCT, regulated the differentiation of CD34+ Fbs into MMP3+ Fbs and APOE+ Fbs through COL6A3 − (ITGAV + ITGB8) interaction. APOE+ Fbs activated IL‐1B+CCL20+ Mφs through the CXCL12/CXCR4 axis. IL‐1B+CCL20+ Mφs and MMP3+ Fbs participated in the local invasion of D‐TGCT.
Yubin Xie+15 more
wiley +1 more source