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Bone remodelling in osteoporosis

Clinical Rheumatology, 1989
Bone remodelling, a highly regulated succession of events, is the temporal sequence of osteoclastic bone resorption and osteoblastic bone formation. Bone loss with age and in osteoporotic patients is due to a disequilibrium between both processus. Bone histomorphometry was the method used to measure these events.
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On the rotary remodelling equilibrium of bone

Computer Methods in Biomechanics and Biomedical Engineering, 2011
The amazing mechanical properties of bone, coupling stiffness, strength and lightweight, are due to a lifelong reorganisation of bone material in response to the prevailing mechanical and chemical ...
Sansalone, V., Naili, S., Dicarlo, A.
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Bone Modeling and Remodeling

Critical Reviews™ in Eukaryotic Gene Expression, 2009
Bone modeling adapts structure to loading by changing bone size and shape and removes damage and so maintains bone strength. Remodeling is initiated by damage producing osteocyte apoptosis, which signals the location of damage via the osteocyte-canalicular system to endosteal lining cells that form the canopy of a bone remodeling compartment (BRC ...
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Bone Remodeling

2014
Skeletal buildup and maintenance is ensured by modeling and remodeling processes. Bone modeling works mainly during organism growth and is characterized by bone formation prevailing on resorption: The two processes are carried out simultaneously but not at the same location.
Brunetti G.   +2 more
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Central Control of Bone Remodelling

Journal of Neuroendocrinology, 2005
The discovery that the brain controls bone remodelling has provided a new paradigm for our understanding of bone biology. This review summarises the genetic, molecular and physiological bases for the central control of bone remodelling and discusses the future directions of this new research field of neuroskeletal biology.
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Bone remodeling and piezoelectricity — II

Journal of Biomechanics, 1973
Abstract It is assumed that the surface aspects of bone remodeling is governed, at least in part, by the piezoelectric polarization produced when the bone is deformed. Bone is considered homogenious and anisotropic with a material axis of symmetry. The model presented is based on four postulates: 1. 1.
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Biochemical Markers of Bone Remodeling

The American Journal of the Medical Sciences, 1996
Bone formation and resorption (or bone turnover) are reflected by levels in blood and urine of various enzymes from bone cells, byproducts of bone matrix synthesis, or breakdown products of bone. These biochemical markers provide information about projected rates of bone loss and can be useful in assessing the effectiveness of antiresorptive therapy ...
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Bone Remodeling Under Pathological Conditions.

Frontiers of oral biology, 2016
Bone is masterfully programmed to repair itself through the coupling of bone formation following bone resorption, a process referred to as coupling. In inflammatory or other conditions, the balance between bone resorption and bone formation shifts so ...
W. Xiao   +4 more
semanticscholar   +1 more source

Cytokines and Bone Remodeling

2008
Publisher Summary Bone is continuously remodeled in normal individuals and this is achieved via a finely regulated balance between the processes of bone formation and resorption mediated by osteoblasts and osteoclasts, respectively. This bone remodeling is regulated, in part, by local factors including cytokines generated in the bone microenvironment.
Julie A. Sterling   +6 more
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Modelling and Remodelling of Bone

2016
Bone is a dynamic organ, highly vascularised and very active metabolically (Fig. 3.1). As the bones are not completely developed at birth, they continue to be formed slowly out of cartilage or connective tissue, which are converted into the hard, lamellar components of the bone.
Christoph Bartl, Reiner Bartl
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