Results 171 to 180 of about 1,937,511 (400)

Benzydamine inhibits osteoclast differentiation and bone resorption via down-regulation of interleukin-1 expression

, 2019
Han Saem Son, Jun‐Ho Lee, Hye In Lee, Narae Kim, You-Jin Jo, Gong-Rak Lee, Seong-Eun Hong, Minjeong Kwon, Nam‐Young Kim, Hyun Jin Kim, Jin Ha Park, Soo Young Lee, Woojin Jeong   +12 more
openalex   +1 more source

Osteoclast-secreted SLIT3 coordinates bone resorption and formation

Journal of Clinical Investigation, 2018
B. Kim, Young‐Sun Lee, Sun-Young Lee, W. Baek, Y. Choi, S. Moon, Seung Hun Lee, Jung-Eun Kim, Eun-Ju Chang, Eun-Young Kim, Jin Yoon, Seung-Whan Kim, S. Ryu, Sun-Kyeong Lee, J. Lorenzo, Seong Hee Ahn, Hyeonmok Kim, Ki‐Up Lee, G. Kim, J. Koh   +19 more
semanticscholar   +1 more source

Nasal Mucosa‐Derived Extracellular Vesicles as a Systemic Antiaging Intervention

Advanced Science, EarlyView.
This study shows that nasal mucosa‐derived extracellular vesicles (nmEVs) exert systemic anti‐ageing effects in mice by restoring circadian rhythm, suppressing cellular senescence, and improving cognitive function. In aged human bone marrow mesenchymal stem cells, nmEVs reverse senescence‐associated phenotypes and reactivate core clock gene expression.
Wentao Shi, Lu Bian, Mengyuan Yu, Jun Wang, Mingzhu Gao, Liping Shen, Xiao Zhang, Zhiliang Huang, Hong Tang, Long Lv, Yunduan Que, Zengli Miao, Xuechao Wu, Qing Wang, Xiaojie Lu   +14 more
wiley   +1 more source

Enhanced Selenium Supplement Extends Lifespan and Delays Multi‐Organs Aging by Regulating the Sik1 Pathway Through Maintaining Calcium Homeostasis

Advanced Science, EarlyView.
Aging involves physiological decline and heightened disease susceptibility, necessitating effective interventions. Redox‐responsive selenium‐loaded nanoparticles (SeMSNs) are developed, which delay cellular senescence by reducing oxidative stress and senescence markers (p16/p21). In aged mice, SeMSNs extend lifespan, improve organ function, and restore
Yang Yu, Jintao Song, Mengjiao Guo, RuZe Ma, Mingyang Du, Zhe Xun, Xu Liu, RongXia Xu, Xiaochun Xie, Peilin Qi, Yujie Chen, Dan Shao, Chao Yang, Liang Wang, Xiaoyu Song, Difei Wang   +15 more
wiley   +1 more source

NFAM1 signaling enhances osteoclast formation and bone resorption activity in Paget's disease of bone

, 2017
Yuvaraj Sambandam, Kumaran Sundaram, Takamitsu Saigusa, Sundaravadivel Balasubramanian, Sakamuri V. Reddy   +4 more
openalex   +1 more source

A Biomechanical Analysis of the Effects of Resorption Cavities on Cancellous Bone Strength [PDF]

, 2006
Christopher J. Hernandez, Atul Gupta, Tony M. Keaveny   +2 more
openalex   +1 more source

Structure‐Tailoring Cerium Nanozymes with Self‐Cascade ROS Scavenging Catalysis Modulate the Microbiota‐Gut‐Joint Axis for Rheumatoid Arthritis Therapy

Advanced Science, EarlyView.
A valence‐engineered CeOX nanozyme, with its Ce3+/Ce4+ ratio precisely controlled within the range of 0.27 to 0.93 through Au deposition, performs a self‐cascade oxidase‐superoxide dismutase‐peroxidase reaction, enabling continuous reactive oxygen species scavenging while minimizing oxygen generation.
Ge Wang, Xueqing Zhang, Boyuan Zhu, Suyue Ding, Dong Yan, Jing Ma, Yafang Xiao, Yafu Wang, Tianjun Ni, Hua Zhang, Weisheng Guo   +10 more
wiley   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Active gelatinase B is identified by histozymography in the cartilage resorption sites of developing long bones [PDF]

, 1999
Eunice R. Lee, Gillian Murphy, Mohamed Elalfy, Maria Antonietta Davoli, Lisa Lamplugh, Andrew Docherty, C. P. Leblond   +6 more
openalex   +1 more source

Bone Resorption Is Regulated by Circadian Clock in Osteoblasts

Journal of Bone and Mineral Research, 2017
T. Takarada, Cheng Xu, H. Ochi, Ryota Nakazato, D. Yamada, Saki Nakamura, Ayumi Kodama, S. Shimba, Michihiro Mieda, Kazuya Fukasawa, Kakeru Ozaki, Takashi Iezaki, Koichi Fujikawa, Y. Yoneda, R. Numano, A. Hida, H. Tei, S. Takeda, E. Hinoi   +18 more
semanticscholar   +1 more source