Results 191 to 200 of about 1,145,483 (297)

HR-pQCT measures of bone in autosomal dominant osteopetrosis highly correlate with fractures and inversely correlate with bone resorption markers. [PDF]

J Bone Miner Res
Warden SJ, Imel EA, Liu Z, Parks-Schenck C, Gebregziabher N, Gerard-O'Riley R, Hart M, Polgreen LE, Econs MJ.   +8 more
europepmc   +1 more source

Meta‐analysis of sotagliflozin, a dual sodium‐glucose‐cotransporter 1/2 inhibitor, for heart failure in type 2 diabetes

ESC Heart Failure, Volume 12, Issue 2, Page 968-979, April 2025.
Abstract Sodium‐glucose co‐transporters (SGLTs) mediate sodium and glucose transport across cell membranes. SGLT2 inhibitors have a recognized place within heart failure (HF) guidelines. We evaluated the effect of sotagliflozin on HF and cardiovascular outcomes in participants with type 2 diabetes. Scopus, Medline, Embase and Central were searched from
Maria Anna Bantounou, Panagiotis Sardellis, Josip Plascevic, Ribeya Awaes‐Mahmood, Justyna Kaczmarek, Daniel Black Boada, Rosa Thuemmler, Sam Philip   +7 more
wiley   +1 more source

TTC26 scaffolds MINDY3-mediated RACK1 deubiquitination to drive osteoclastogenesis and pathological bone resorption. [PDF]

J Orthop Translat
Gao Y, Lai B, Yan R, He J, Lu T, Yang S, Chen J, Gao R, Jiang H, Zhou X.   +9 more
europepmc   +1 more source

Severe skeletal fragility in SCN8A‐related developmental and epileptic encephalopathy

Epilepsia, EarlyView.
Abstract In this child with a phenotype compatible with the SCN8A gain‐of‐function spectrum, more than 20 bone fractures were documented. Together with previously reported cases, these observations raise the possibility that skeletal fragility may represent an underrecognized feature of the clinical spectrum associated with pathogenic SCN8A variants ...
Adélia Maria de Miranda Henriques‐Souza, Kette D. Valente   +1 more
wiley   +1 more source

Identification of hub genes and molecular networks involved in alveolar bone resorption based on bioinformatics analysis. [PDF]

Sci Rep
Lv W, Zhang W, Zheng M, Wang X, Lin D, Hu S, Cai X, Zhang M, Li C, Wu Y.   +9 more
europepmc   +1 more source

Review of articular cartilage repair techniques and their application in the horse

Equine Veterinary Journal, EarlyView.
Abstract Articular cartilage lesions represent a significant career‐limiting problem in athletic horses. A healthy articular cartilage surface is vital for optimal joint function, and defects can result in irreversible degenerative changes. Successful treatment of cartilage lesions remains a long‐standing challenge for orthopaedic surgeons, prompting ...
Charlotte K. Barton, Brad B. Nelson, Laurie R. Goodrich   +2 more
wiley   +1 more source

Vitamin K-dependent carboxylation in osteoblasts regulates bone resorption through GAS6 in male mice. [PDF]

Bone Res
Pata M, Pham DNT, Lacombe J, Reddy BA, Kim YW, Ahmed AGA, Murshed M, Ferron M.   +7 more
europepmc   +1 more source

Serum osteocalcin is associated with scintigraphic abnormalities in lame and clinically sound racehorses

Equine Veterinary Journal, EarlyView.
Abstract Background Musculoskeletal injury is a major welfare and economic challenge in racehorses, with stress‐related bone injury contributing to training interruption and catastrophic failure. Advanced imaging modalities can detect early skeletal pathology but remain limited in routine screening environments.
Peter Tually, Dominique Blache, Jack Meadows, Shiphrah Tagore, Paul O'Callaghan, Matilda Hathway, Ian Fulton, Geoffrey Currie   +7 more
wiley   +1 more source

Solasodine, a Natural Steroidal Alkaloid, Attenuates RANKL-Induced Osteoclastogenesis and Bone Resorption: A Study Based on Network Pharmacology and Experimental Validation. [PDF]

J Cell Mol Med
Jiang Y, Jin Z, Ji X, Wang M, Cao Z.
europepmc   +1 more source