Keeping bone resorption markers very low for 1 year after denosumab prevents bone loss at 2 years: the ReoLaus study. [PDF]
Liebich G +3 more
europepmc +1 more source
Integrated approach to menopausal hormone therapy in women with cardiovascular risk factors or established ischemic heart disease, from early treatment initiation and risk stratification to individualized therapy, multidisciplinary follow‐up, and health‐system recommendations.
Chiara Benedetto +9 more
wiley +1 more source
Radiographic bone resorption after reverse total shoulder arthroplasty using a single onlay platform: risk factors and distribution patterns in a Japanese cohort. [PDF]
Nozu T +7 more
europepmc +1 more source
This review systematically summarizes the central role of cysteine peptidases in modulating antigen‐presenting cell (APC) function and antitumor immune responses, highlighting their critical significance in overcoming tumor immune evasion. Current research has established that cysteine peptidase subtypes, including cathepsins B, S, L, and X, exert ...
Yimao Wu +7 more
wiley +1 more source
Cyanidin-3-Glucoside Supplementation Modulates Bone Resorption in Experimental Apical Periodontitis. [PDF]
Ricci R +9 more
europepmc +1 more source
ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential
ATP citrate lyase (ACLY) is a central metabolic hub that diverts mitochondrial citrate to fuel de novo lipogenesis, cholesterol biosynthesis, and protein acetylation. Given its robust correlation with pathological changes in multiple human diseases, ACLY inhibitors featuring distinct pharmacological strengths have been developed for therapeutic ...
Wenbiao Wang +5 more
wiley +1 more source
Selective disruption of microtubule formation at the nuclear envelope impairs the bone resorption capacity of osteoclasts. [PDF]
Vergarajauregui S +4 more
europepmc +1 more source
ABSTRACT Objective As artificial intelligence (AI) tools gain traction in healthcare, their role in periodontal diagnostics remains largely unexplored. This study evaluated the diagnostic accuracy of ChatGPT‐4 in applying the 2017 Classification of Periodontal and Peri‐Implant Diseases and Conditions compared to US dental school faculty, with the goal ...
Ellie Y. Ji +10 more
wiley +1 more source
Cell signaling and transcriptional regulation of osteoclast lineage commitment, differentiation, bone resorption and diseases. [PDF]
Zhu S, Yan MQ, Masson A, Chen W, Li YP.
europepmc +1 more source
Perceived Educational Value of a Self‐Developed 3D‐Printed Pediatric Dentistry Simulator
ABSTRACT Purpose To design and assess a 3D‐printed pediatric dentistry simulator and to evaluate its perceived educational value and realism through student and expert feedback. Methods A maxillary simulator that is mountable on phantom heads was developed and produced by desktop stereolithography with single‐use inserts, enabling proximal caries ...
Michel Benyamin +11 more
wiley +1 more source

