Results 181 to 190 of about 1,831,965 (356)

Bacterial Capture‐Killing Capsules with Remodeling Bone Immune Microenvironment for the Effective Treatment of Osteomyelitis

Advanced Science, EarlyView.
The PC‐O@TOB capsules are designed to exhibit bactericidal effects, regulate the bone immune microenvironment by promoting M2 macrophage polarization, eliminate excessive ROS, and enhance bone regeneration, providing a novel multi‐dimensional approach for the treatment of osteomyelitis.
Dong Yang, Chang Shu, Chengwei Xu, Xingjie Zan, Shaoyin Wei, Chenglong Wang, Lianxin Li   +6 more
wiley   +1 more source

Rainbow Trout Hypocalcin Stimulates Bone Resorption in Embryonic Mouse Calvaria in Vitro in A Pth-Like Fashion [PDF]

, 1989
Floris P. J. G. Lafeber, M. P. M. Herrmann‐Erlee, Gert Flik, S.E. Wendelaar Bonga   +3 more
openalex   +1 more source

Cartilage‐Penetrating Framework Nucleic Acid Nanoparticles Ameliorate Osteoarthritis by Promoting Drug Delivery and Chondrocyte Uptake

Advanced Science, EarlyView.
Based on the poor cartilage penetration of tFNA, a novel tFNA‐2WL with excellent cartilage permeability and perfect chondrocyte endocytosis properties is designed and fabricated. As a result, tFNA‐2WL has a nearly seven‐fold increase in the penetration depth into the cartilage, with the same excellent cell entry properties as tFNA.
Kui Huang, Qiumei Li, Huixuan Lin, Qian Shen, Yaping Wu, Taoran Tian, Chuan Ma, Sirong Shi, Jingang Xiao, Yunfeng Lin   +9 more
wiley   +1 more source

Inhibition of bone resorption in culture by inhibitors of thiol proteinases [PDF]

, 1980
Jean‐Marie Delaissé, Yves Eeckhout, Gilbert Vaes   +2 more
openalex   +1 more source

Novel Molecules that Regulate Bone Formation and Bone Resorption [PDF]

, 2011
Osteoporosis is a disease characterized by decreased bone mass and microarchitectural deterioration of bone. Bone loss occurs when the increased bone resorption that occurs with age is not compensated by a corresponding increase in bone formation ...
Linares, Gabriel Robert
core   +1 more source

Microenvironmental Modulation for Therapeutic Efficacy of Extracellular Vesicles

Advanced Science, EarlyView.
Recent studies highlighted the heterogeneity of EVs and the influence of microenvironmental signals on their therapeutic efficacy. This review offers a comprehensive overview of strategies and mechanisms to optimize the therapeutic efficacy of EVs through physical, biochemical, and mechanical modulation.
Bilu Xiang, Shiying Zhang, Irene Shuping Zhao, Xueqi Gan, Yang Zhang   +4 more
wiley   +1 more source

Clinical and radiographic findings without the use of bone substitute materials in extraction sockets and delayed implant placement- A case series

Journal of Oral Biology and Craniofacial Research, 2020
Aim: To observe clinically and radiographically (CBCT), the extent of bone resorption in extraction socket without the use of bone graft substitutes and delayed implant placement. Material and methods: 50 compliant patients were selected for study.
Lanka Mahesh, Jose Luis Calvo Guirado, Sagrika Shukla, Varun Raj Kumar, Yuvika Raj Kumar   +4 more
doaj  

Periodontal Bone Loss Analysis via Keypoint Detection With Heuristic Post-Processing [PDF]

arXiv
Calculating percentage bone loss is a critical test for periodontal disease staging but is sometimes imprecise and time consuming when manually calculated. This study evaluates the application of a deep learning keypoint and object detection model, YOLOv8-pose, for the automatic identification of localised periodontal bone loss landmarks, conditions ...
arxiv  

Direct extraction and assay of bone tissue collagenase and its relation to parathyroid-hormone-induced bone resorption [PDF]

, 1986
Yves Eeckhout, Jean‐Marie Delaissé, Gilbert Vaes   +2 more
openalex   +1 more source

Customized Hydrogel System for the Spatiotemporal Sequential Treatment of Periodontitis Propelled by ZEB1

Advanced Science, EarlyView.
Through elaborate design, a biodegradable scaffold with excellent mechanical properties and suitability is fabricated, providing spatial support for subsequent physiological activities. The prepared GA‐HBC‐LIC hydrogel possesses sequential antibacterial, antioxidant, anti‐inflammatory and immunomodulatory functions, offering a suitable chemical and ...
Jiafei Chen, Xiaoxu Guan, Lina Chen, Bingzhu Zheng, Feiyu Li, Chao Fang, Yike Fu, Xiang Li, Huiming Wang, Yi Zhou   +9 more
wiley   +1 more source