Results 291 to 300 of about 1,847,810 (404)

Meta‐analysis of sotagliflozin, a dual sodium‐glucose‐cotransporter 1/2 inhibitor, for heart failure in type 2 diabetes

ESC Heart Failure, Volume 12, Issue 2, Page 968-979, April 2025.
Abstract Sodium‐glucose co‐transporters (SGLTs) mediate sodium and glucose transport across cell membranes. SGLT2 inhibitors have a recognized place within heart failure (HF) guidelines. We evaluated the effect of sotagliflozin on HF and cardiovascular outcomes in participants with type 2 diabetes. Scopus, Medline, Embase and Central were searched from
Maria Anna Bantounou, Panagiotis Sardellis, Josip Plascevic, Ribeya Awaes‐Mahmood, Justyna Kaczmarek, Daniel Black Boada, Rosa Thuemmler, Sam Philip   +7 more
wiley   +1 more source

Protective Effect of Methyl Sulfonyl Methane on the Progression of Age-Induced Bone Loss by Regulating Oxidative Stress-Mediated Bone Resorption. [PDF]

Antioxidants (Basel)
Zhang D, Wang L, Tang L, Zhang Y, Zhang H, Zou L.   +5 more
europepmc   +1 more source

Intracranial stimulation for pediatric refractory epilepsy: A single institutional experience using evolving therapies

Epilepsia Open, EarlyView.
Abstract Objective Neuromodulation for pediatric refractory epilepsy (PRE) is preferred when the seizure onset zone is not amenable to surgical resection, due to multifocal onset or involvement of eloquent cortex. Given its rapidly evolving landscape, we describe our institutional experience with neurostimulation therapies including deep brain ...
Rohin Singh, Megan M. J. Bauman, Karimul Islam, Panagiotis Kerezoudis, Sanjeet S. Grewal, Jonathon J. Parker, Jamie J. Van Gompel, Kai J. Miller, Brian N. Lundstrom, Keith Starnes   +9 more
wiley   +1 more source

FTO-associated osteoclastogenesis promotes alveolar bone resorption in apical periodontitis male rat via the HK1/USP14/RANK pathway. [PDF]

Nat Commun
Qian Y, Wu J, Yang W, Lyu R, You Q, Li J, He Q, Zhuang Y, Wang W, Wang Y, Zhu Y, Wu Z, Chen D.   +12 more
europepmc   +1 more source

Dissociation between bone resorption and bone formation in osteopenic transgenic mice

, 1998
David A. Corral, Michael Amling, Matthias Priemel, Evelyn Loyer, Sébastien Fuchs, Patricia Ducy, Roland Baron, Gérard Karsenty   +7 more
openalex   +1 more source

Effects of perampanel on bone health in adult patients with epilepsy

Epilepsia Open, EarlyView.
Abstract Objective The objective was to assess the effects of perampanel (PER) on bone metabolism and bone mineral density (BMD) in adult patients with epilepsy. Methods This retrospective study included consecutive patients admitted to the Epilepsy Center of Sichuan Provincial People's Hospital from January 2023 to June 2024.
Mingxing Yu, Nana Zhang, Chunyan Chen, Yuxuan He, Jing Meng, Wen Luo, Yi Liang, Yi Guo, Liang Yu   +8 more
wiley   +1 more source

Potential for Drug Repositioning of Midazolam as an Inhibitor of Inflammatory Bone Resorption. [PDF]

Int J Mol Sci
Harigaya H, Chiba-Ohkuma R, Karakida T, Yamamoto R, Fujii-Abe K, Kawahara H, Yamakoshi Y.   +6 more
europepmc   +1 more source

The palaeohistology of pterosaur bone: an overview [PDF]

, 2008
Steel, Lorna
core   +1 more source

Studies on Novel Bone Resorption Inhibitors. II. Synthesis and Pharmacological Activities of Fused Aza-heteroarylbisphosphonate Derivatives.

, 1998
Makoto Takeuchi, S Sakamoto, Kousei Kawamuki, Hiroyuki Kurihara, Hideaki NAKAHARA, Yasuo ISOMURA   +5 more
openalex   +2 more sources

Biomaterials‐Involved Construction of Extracellular Matrices for Tumor Blockade Therapy

Exploration, EarlyView.
Extracellular matrices (ECMs) play a crucial role in tumor growth and metastases by providing structural support and facilitating tumor cell proliferation. In this review, we explore the development of artificial ECMs engineered through biomineralization, fibrogenesis, and gelation. These bioinspired ECMs create a protective barrier around tumor cells,
Jinfeng Sun, Yang Liu, Jingshan Sun, Jianxun Ding, Xuesi Chen   +4 more
wiley   +1 more source