Biomaterial Investigations in Dentistry, 2022 Statement of the problem: Narrow implants have been recommended in high esthetic demand regions to ensure greater buccal bone thickness (BBT) and minimize soft-tissue recession due to insufficient bone support.
Ivan Onone Gialain +5 more
doaj +1 more source
Multiple Idiopathic Cervical Root Resorption: A Challenge for a Transdisciplinary Medical-Dental Team [PDF]
arXiv, 2021 While tooth root resorption is a normal physiological process required for resorption and exfoliation of primary teeth, root resorption of adult teeth is largely pathological. This perspective focuses on multiple idiopathic cervical root resorption (MICRR), an aggressive form of external root resorption that occurs near the cemento-enamel junction (CEJ)
arxiv
Concurrent consideration of cortical and cancellous bone within continuum bone remodelling [PDF]
, 2020 Continuum bone remodelling is an important tool for predicting the effects of mechanical stimuli on bone density evolution. While the modelling of only cancellous bone is considered in many studies based on continuum bone remodelling, this work presents an approach of modelling also cortical bone and the interaction of both bone types.
arxiv +1 more source
Bone resorption: supporting immunometabolism [PDF]
Biology Letters, 2018 Activation of the immune system is associated with an increase in the breakdown of various peripheral tissues, including bone. Despite the widely appreciated role of inflammatory mediators in promoting bone resorption, the functional value behind this process is not completely understood.
Gustav van Niekerk +2 more
openaire +2 more sources
FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H2O2 accumulation
Nature Communications, 2014 Besides their cell-damaging effects in the setting of oxidative stress, reactive oxygen species (ROS) play an important role in physiological intracellular signalling by triggering proliferation and survival.
S. M. Bartell +12 more
semanticscholar +1 more source
Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations
Advanced Functional Materials, EarlyView.Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan +4 more
wiley +1 more source
Toddaculin, Isolated from of Toddalia asiatica (L.) Lam., Inhibited Osteoclastogenesis in RAW 264 Cells and Enhanced Osteoblastogenesis in MC3T3-E1 Cells. [PDF]
PLoS ONE, 2015 Osteoporosis with bone loss is widely recognized as a major health problem. Bone homeostasis is maintained by balancing bone formation and bone resorption.
Akio Watanabe +13 more
doaj +1 more source
Short-term Osteoclastic Activity Induced by Locally High Concentrations of Recombinant Human Bone Morphogenetic Protein–2 in a Cancellous Bone Environment [PDF]
, 2009 Study Design. An experimental study investigating osteoclastic activity induced by rhBMP-2 in sheep. Objective. To examine the effects of increasing local rhBMP-2 concentration on osteoclastic response and peri-implant bone resorption.
Badura, Jeffrey +5 more
core +1 more source
Activation of the P2Y2 receptor regulates bone cell function by enhancing ATP release [PDF]
, 2017 Bone cells constitutively release ATP into the extracellular environment where it acts locally via P2 receptors to regulate bone cell function. Whilst P2Y2 receptor stimulation regulates bone mineralisation, the functional effects of this receptor in ...
Arnett, T R +5 more
core +2 more sources
Advanced Functional Materials, EarlyView.The temporary transition of macrophages from a pro‐inflammatory phenotype of macrophages (M1) to an anti‐inflammatory phenotype of macrophages (M2) is crucial for tissue repair and regeneration processes. Bacterial outer membrane vesicles (OMVs) are utilized as a “trojan horse” for specific M1 macrophage‐targeting and anti‐inflammatory drug delivery ...
Donglin Cai +9 more
wiley +1 more source