Results 71 to 80 of about 1,831,965 (356)

Macrophage Depletion Abates Porphyromonas gingivalis–Induced Alveolar Bone Resorption in Mice

open access: yesJournal of Immunology, 2014
The role of the macrophage in the immunopathology of periodontitis has not been well defined. In this study, we show that intraoral inoculation of mice with Porphyromonas gingivalis resulted in infection, alveolar bone resorption, and a significant ...
Roselind S. Lam   +9 more
semanticscholar   +1 more source

Mesenchymal Stem Cells‐Derived Extracellular Vesicles Mimetics as Osteoinductive Mediators for Bone Healing

open access: yesAdvanced Functional Materials, EarlyView.
Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan   +4 more
wiley   +1 more source

Osteoclast biology in bone resorption: a review

open access: yesSTEMedicine, 2020
What we know about bone resorption has changed a lot in the last few decades. The osteoclast is the only cell to nibble and break down the bone, and in the formation and resorption of bone tissue, osteoclasts play an important role.
Chao Fu, Ruyi Shi
doaj   +1 more source

Peri-implant bone resorption risk of anterior maxilla narrow single implants: a finite-element analysis

open access: yesBiomaterial Investigations in Dentistry, 2022
Statement of the problem: Narrow implants have been recommended in high esthetic demand regions to ensure greater buccal bone thickness (BBT) and minimize soft-tissue recession due to insufficient bone support.
Ivan Onone Gialain   +5 more
doaj   +1 more source

Multiple Idiopathic Cervical Root Resorption: A Challenge for a Transdisciplinary Medical-Dental Team [PDF]

open access: yesarXiv, 2021
While tooth root resorption is a normal physiological process required for resorption and exfoliation of primary teeth, root resorption of adult teeth is largely pathological. This perspective focuses on multiple idiopathic cervical root resorption (MICRR), an aggressive form of external root resorption that occurs near the cemento-enamel junction (CEJ)
arxiv  

Concurrent consideration of cortical and cancellous bone within continuum bone remodelling [PDF]

open access: yes, 2020
Continuum bone remodelling is an important tool for predicting the effects of mechanical stimuli on bone density evolution. While the modelling of only cancellous bone is considered in many studies based on continuum bone remodelling, this work presents an approach of modelling also cortical bone and the interaction of both bone types.
arxiv   +1 more source

Glucose-dependent insulinotropic polypeptide inhibits bone resorption in humans.

open access: yesJournal of Clinical Endocrinology and Metabolism, 2014
BACKGROUND In humans, the pronounced postprandial reduction in bone resorption (decreasing bone resorption markers by around 50%) has been suggested to be caused by gut hormones.
A. Nissen   +5 more
semanticscholar   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

open access: yesAdvanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan   +4 more
wiley   +1 more source

Toddaculin, Isolated from of Toddalia asiatica (L.) Lam., Inhibited Osteoclastogenesis in RAW 264 Cells and Enhanced Osteoblastogenesis in MC3T3-E1 Cells. [PDF]

open access: yesPLoS ONE, 2015
Osteoporosis with bone loss is widely recognized as a major health problem. Bone homeostasis is maintained by balancing bone formation and bone resorption.
Akio Watanabe   +13 more
doaj   +1 more source

Focusing on OB-OC-MΦ Axis and miR-23a to Explore the Pathogenesis and Treatment Strategy of Osteoporosis

open access: yesFrontiers in Endocrinology, 2022
Osteoporosis is a bone metabolic disorder characterized by decreased bone density and deteriorated microstructure, which increases the risk of fractures.
Tian-Liang Ma   +9 more
doaj   +1 more source

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