Results 71 to 80 of about 14,966 (263)

The Osteoblastic Microenvironment Determines the Fate of Breast Cancer Cells Disseminated in the Bone Marrow

open access: yesAdvanced Science, EarlyView.
This study revealed how the osteoblastic microenvironment determines the fate of cancer cells disseminated in bone, with a focus on whether they colonize, reside in quiescence, or reactivate from dormancy. Targeting integrin signaling may offer promising strategies for preventing quiescent cancer cells reactivation and bone colonization.
Hong‐Li Wang   +7 more
wiley   +1 more source

Short-term cone beam CT study on bone mass changes post touch-controlled minimally invasive mandibular molar implant

open access: yesScientific Reports
This study aimed to investigate the change of peri-implant bone mass after touch-controlled, minimally invasive implantation in the mandibular first molar region by cone-beam computed tomography (CBCT).
Wenchao Li   +7 more
doaj   +1 more source

Association of Computed Tomography Values of the Tooth Root and Alveolar Bone with Orthodontic Root Resorption

open access: diamond, 2023
Mayu Kurasawa-Kanao   +6 more
openalex   +2 more sources

Gαi1/3 Is a Novel Regulatory Target for RANKL Signal Transduction and Osteoporosis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Osteoporosis, characterized by progressive bone loss and increased fracture risk, is a growing concern as the population ages. Current treatments, though advanced, remain limited, underscoring the necessity for novel therapeutic targets. Recent studies have shown that the immune system plays a key role in osteoporosis, with osteoclasts driving
Chaowen Bai   +15 more
wiley   +1 more source

Isoliquiritigenin Decreases Bone Resorption and Osteoclast Differentiation [PDF]

open access: green, 2022
Kaitlyn M. Joyce   +9 more
openalex   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

open access: yesAdvanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong   +6 more
wiley   +1 more source

NIR‐Activatable Domino Cascade Catalysis Nanozyme Reactor for Multi‐Mechanism Synergistic Immunotherapy in Bladder Cancer

open access: yesAdvanced Science, EarlyView.
This study presents an intravesical delivery strategy of ferroptosis‐ and immunity‐inducing nanozyme‐loaded thermoresponsive hydrogels (FMCC@PNH) for enhanced bladder cancer therapy. Abstract Current intravesical therapies for bladder cancer after resection are limited by poor tissue penetration, off‐target effects, and insufficient efficacy.
Yongnan Jiang   +11 more
wiley   +1 more source

Bone resorption in incompletely impacted mandibular third molars and acute pericoronitis

open access: yesClinical, Cosmetic and Investigational Dentistry, 2009
Minoru Yamaoka, Yusuke Ono, Masahiro Takahashi, Ryosuke Doto, Kouichi Yasuda, Takashi Uematsu, Kiyofumi FurusawaMatsumoto Dental University, School of Dentistry, Shiojiri, Nagano, JapanAbstract: Acute pericoronitis (AP) arises frequently in incompletely ...
Minoru Yamaoka   +4 more
doaj  

CELLULAR BIOLOGY OF BONE RESORPTION

open access: yesBiological Reviews, 1993
SummaryPast knowledge and the recent developments on the formation, activation and mode of action of osteoclasts, with particular reference to the regulation of each individual step, have been reviewed. The following conclusions of consensus have emerged.1.
MONE ZAIDI   +10 more
openaire   +3 more sources

Gut–Metabolome–Proteome Interactions in Age‐Related Hearing Loss: Insights from Fecal Microbiota Transplantation and Multi‐Omics Analyses

open access: yesAdvanced Science, EarlyView.
Germ‐free (GF) mice receiving fecal microbiota transplantation (FMT) reveal microbiota‐dependent effects on auditory aging. Integrated metagenomic, metabolomic and proteomic profiling maps gut–inner ear network and highlights 5‐hydroxytryptophan (5‐HTP) as a microbiota‐linked metabolic hub in age‐related hearing loss (ARHL).
Ting Yang   +12 more
wiley   +1 more source

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