Results 31 to 40 of about 64,880 (302)

Bone substitute effect on vascularization and bone remodeling after application of phVEGF165 transfected BMSC

, 2012
VEGF (vascular endothelial growth factor) promotes vascularization and remodeling of bone substitutes. The aim of this study was to examine the effect of distinct resorbable ceramic carriers on bone forming capacities of VEGF transfected bone marrow ...
Beverungen, Mirjam, Wieland, Julia, Michael Fehr, Florian Geiger, Philip Kasten, Mirjam Beverungen, Helga Lorenz, Geiger, Florian, Fehr, Michael, Lorenz, Helga, Julia Wieland, Kasten, Philip   +11 more
core   +1 more source

Pharmacokinetics of gentamicin eluted from a regenerating bone graft substitute:In vitro and clinical release studies [PDF]

, 2016
OBJECTIVES: Deep bone and joint infections (DBJI) are directly intertwined with health, demographic change towards an elderly population, and wellbeing.The elderly human population is more prone to acquire infections, and the consequences such as pain ...
Nilsson, M, Hettwer, W,, Stravinskas, M, Stravinskas, M,, Ferguson, J,, Hettwer, W, McNally, M A,, McNally, M A, Nilsson, M,, Tarasevicius, S, Horstmann, P, Lidgren, L,, Petersen, M M,, Horstmann, P,, Lund University., Lidgren, L, Tarasevicius, S,, Ferguson, J, Petersen, M M   +18 more
core   +1 more source

Bone substitute fracture in open wedge high tibial osteotomy: Comparison of two different bone substitutes

Journal of Joint Surgery and Research
Purpose: The aim of this study was to retrospectively compare bone substitute fracture patterns and outcomes in patients who underwent open wedge high tibial osteotomy (OWHTO) with OSferion60 or OSferion60 Marvelous bone substitutes.
Ryuichi Nakamura, Masaki Amemiya, Kaori Matsumoto, Ippei Yoshida, Fumiyoshi Kawashima, Tomoyuki Shimakawa, Akira Okano   +6 more
doaj   +1 more source

Generation of osteoinductive grafts by three-dimensional perfusion culture of human bone marrow cells into porous ceramic scaffolds [PDF]

, 2005
The main aims of this thesis were (i) to identify and develop a system that could be reproducibly used to streamline manufacture of osteoinductive grafts based on human bone marrow stromal cells (BMSC) in the context of regenerative medicine, (ii) to ...
Braccini, Alessandra
core   +1 more source

Spinal fusions: bone and bone substitutes [PDF]

European Spine Journal, 2000
Vertebral arthrodesis is one of the most commonly performed, yet incompletely understood, procedures in spinal surgery. Despite major progress in internal fixation techniques, the high rate of nonunions indicates that physiologic, biologic and molecular events that are crucial to this process are not well known.
openaire   +2 more sources

The scale-up of a tissue engineered porous hydroxyapatite polymer composite scaffold for use in bone repair: an ovine femoral condyle defect study

, 2014
The development of an osteogenic bone graft substitute has important practical and cost implications in many branches of medicine where bone regeneration is required.
Oreffo, Richard O. C., Purcell, Matthew, Tayton, Edward, Dunlop, Douglas G., Shakesheff, Kevin M., Goodship, Allen, Fowler, Darren, Smith, James O., Howdle, Steven M., Oreffo, Richard O.C., Blunn, Gordon, Lanham, Stuart, Tayton, Edward R.   +12 more
core   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Human endothelial-like differentiated precursor cells maintain their endothelial characteristics when cocultured with mesenchymal stem cell and seeded onto human cancellous bone [PDF]

, 2013
Introduction. Cancellous bone is frequently used for filling bone defects in a clinical setting. It provides favourable conditions for regenerative cells such as MSC and early EPC.
Marzi, Ingo, Dirk Henrich, Barker, John Howard, John Barker, Cancellous Bone, Henrich, Dirk, Ingo Marzi, Seebach, Caroline, Joerg Warzecha, Caroline Seebach, Wilhelm, Kerstin, Warzecha, Jörg, Frank, Johannes, Kerstin Wilhelm, Johannes Frank   +14 more
core   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Physical and chemical characterisation of crude meat and bone meal combustion residue: “waste or raw material?” [PDF]

, 2005
As a result of the recent bovine spongiform encephalopathy (BSE) crisis in the European beef industry, the use of animal by-product is now severely controlled.
Deydier, Eric, Richard Guilet, Stéphanie Sarda, Guilet, Richard, Sarda, Stéphanie, Patrick Sharrock, Sharrock, Patrick, Eric Deydier   +7 more
core   +1 more source