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Bone Substitutes

The Cleft Palate Craniofacial Journal, 2000
The search for the ideal bone substitute began hundreds of years ago, and continues today. While numerous choices have been proposed and tested, with varying degrees of success, there remain many challenges related to the use of bone substitutes in craniofacial reconstruction.
Sailer HF, Weber FE
openaire   +5 more sources

Bone and bone substitutes

Periodontology 2000, 1999
Bone replacement grafts will play a continuing role in periodontal and other regenerative therapy. Several choices are available to the clinician including autogenous, allogeneic, xenogeneic and a variety of alloplastic materials. Except for fresh autogenous bone, bone replacement graft(s) do not provide the cellular elements necessary for osteogenesis
H F, Nasr   +2 more
openaire   +2 more sources

Bone grafts and their substitutes

The Bone & Joint Journal, 2016
The continual cycle of bone formation and resorption is carried out by osteoblasts, osteocytes, and osteoclasts under the direction of the bone-signaling pathway. In certain situations the host cycle of bone repair is insufficient and requires the assistance of bone grafts and their substitutes.
Y, Fillingham, J, Jacobs
openaire   +2 more sources

A Review of Bone Substitutes

Oral and Maxillofacial Surgery Clinics of North America, 2007
The use of bone grafts in the repair of defects has a long history of success, primarily with the use of autologous bone. With increasing technologic advances, researchers have been able to broaden the spectrum of grafting materials to allografts, xenografts, and synthetic materials, which provide the surgeon and patient with options, each with unique ...
Solon T, Kao, Daniel D, Scott
openaire   +2 more sources

Bone-graft substitutes

The Lancet, 1999
Bone is the most commonly transplanted tissue except for blood. An autogenous bone graft was first used successfully in 1875 when Nussbaum harvested the ulna for bone to correct a skeletal defect? Today, in the U S A alone, autogenous bone grafting is done in about 200 000 surgical cases annually.
A, Van Heest, M, Swiontkowski
openaire   +2 more sources

Bone substitutes: An update

Injury, 2005
Autograft is considered ideal for grafting procedures, providing osteoinductive growth factors, osteogenic cells, and an osteoconductive scaffold. Limitations, however, exist regarding donor site morbidity and graft availability. Allograft on the other hand, posses the risk of disease transmission.
Peter V, Giannoudis   +2 more
openaire   +2 more sources

Bone Substitutes

Der Orthopade, 2003
A large variety of different bone substitutes are available for the treatment of congenital or acquired bone defects as an alternative to bone transplantation. Complications associated with graft harvesting, limited donor resources, and the potential risk of transmission of infectious diseases have led to the development of multiple concepts of new ...
K.R. Swartz, G.R. Trost
  +5 more sources

Hydroxyapatite as a bone substitute

Journal of the American Podiatric Medical Association, 1999
A bone substitute eliminates the need for autogenous and allogeneic bone grafting, along with the complications unique to each. Coralline hydroxyapatite is a synthetic bone void filler manufactured from marine coral, which has a natural trabecular structure similar to that of cancellous bone.
K T, Mahan, M J, Carey
openaire   +2 more sources

Role of Bone Substitutes

Clinical Orthopaedics and Related Research, 1996
Approximately 500 million years ago, the Paleozoic era heralded an evolutionary marvel: the skeleton. Unique to this evolutionary development was the capacity for regeneration: the physiologic renewal of embryologically derived tissue. Many of the cellular and molecular components for bone regeneration have been identified (bone morphogenetic proteins),
J O, Hollinger   +3 more
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Bone Grafts and Substitutes

Journal of Long-Term Effects of Medical Implants, 2006
Bone is a complex organ system that provides structural support for the human body while also serving an important protective function for the internal organs. It is estimated that over 500,000 bone-grafting procedures are performed annually in the United States.
C Suzanne, Cutter, Babak J, Mehrara
openaire   +2 more sources

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