Results 1 to 10 of about 58,852 (158)

Poly(lactic-co-glycolic acid)-based composite bone-substitute materials

Bioactive Materials, 2021
Research and development of the ideal artificial bone-substitute materials to replace autologous and allogeneic bones for repairing bone defects is still a challenge in clinical orthopedics. Recently, poly(lactic-co-glycolic acid) (PLGA)-based artificial
Duoyi Zhao, Tongtong Zhu, Xiuli Zhuang   +2 more
exaly   +3 more sources

Histomorphometric Evaluation of Socket Preservation Healing Using Xenogeneic Bone Substitute Combined with Statin: A Prospective Split-Mouth Clinical Pilot Study [PDF]

Acta Stomatologica Croatica
Objective: Statins exhibit pleiotropic effects on bone metabolism, including osteogenic and angiogenic activity. The aim of this pilot study was to evaluate whether local application of simvastatin combined with a bovine-derived xenogeneic bone ...
Tomislav Katanec, Luka Šimunović, Robert Likić, Igor Smojver, Stjepanka Lešić, Ivica Pelivan, Dragana Gabrić   +6 more
doaj   +2 more sources

Plant-Derived Bone Substitute Presents Effective Osteointegration in Several Clinical Settings: A Pilot Study from a Single Center [PDF]

Bioengineering
Background: Bone loss management is a tough challenge in orthopedic and trauma surgery that is generally treated using graft or substitute. Bone is the second most common transplanted tissue behind blood.
Gianluca Conza, Adriano Braile, Antonio Davide Vittoria, Nicola Di Cristofaro, Annalisa Itro, Gabriele Martin, Gabriella Toro, Pier Francesco Indelli, Vincenzo Salini, Giuseppe Toro   +9 more
doaj   +2 more sources

Posterolateral Arthrodesis in Lumbar Spine Surgery Using Autologous Platelet-Rich Plasma and Cancellous Bone Substitute: An Osteoinductive and Osteoconductive Effect

Global Spine Journal, 2014
Study Design Prospective cohort study. Objectives To analyze the effectiveness and practicality of using cancellous bone substitute with platelet-rich plasma (PRP) in posterolateral arthrodesis.
Roberto Tarantino, Cristina Mancarella, Marika Rullo   +2 more
exaly   +2 more sources

Duration and timing of bisphosphonate treatment as factors determining osteoblast mineralization

Journal of Oral Biology and Craniofacial Research, 2022
Background: Alendronate is a drug for the treatment of excessive bone resorption. Alendronate reduces osteoblast viability and mineralization in a dose-dependent manner. Other views of alendronate could affect mineralization.
Somying Patntirapong
doaj   +1 more source

Timing of geranylgeraniol addition increases osteoblast activities under alendronate condition

Journal of Oral Biology and Craniofacial Research, 2021
Background: Alendronate (ALN), a nitrogen-containing bisphosphonate, is prescribed to treat bone diseases. ALN acts as an inhibitor of enzymes in the mevalonate pathway, which results in reducing osteoblast viability and mineralization.
Harikarn Mungpayabarn, Somying Patntirapong   +1 more
doaj   +1 more source

Optimizing Spinal Fusion Cage Design to Improve Bone Substitute Filling on Varying Disc Heights: A 3D Printing Study

Bioengineering, 2023
The success of spinal fusion surgery relies on the precise placement of bone grafts and minimizing scatter. This study aims to optimize cage design and bone substitute filling methods to enhance surgical outcomes.
Cheng-Min Shih, Cheng-Hung Lee, Kun-Hui Chen, Chien-Chou Pan, Yu-Chun Yen, Chun-Hsiang Wang, Kuo-Chih Su   +6 more
doaj   +1 more source

Biologically modified implantation as therapeutic bioabsorbable materials for bone defect repair

Regenerative Therapy, 2022
For decades, researches have concentrated on the mechanical properties, biodegradation, and biocompatibility of implants used in the therapy of large size bone defect.
Chao Li, Hongzhi Lv, Yawei Du, Wenbo Zhu, Weijie Yang, Xiumei Wang, Juan Wang, Wei Chen   +7 more
doaj   +1 more source

Evaluation of a New Porcine Bone Graft on the Repair of Surgically Created Critical Bone Defects in Rat Calvaria: Histomorphometric and Microtomographic Study

Journal of Functional Biomaterials, 2022
The aim of this study was to evaluate the use of a new porcine bone graft in rat calvaria bone defects. Critical defects were surgically created in 24 rats that were divided into four experimental groups according to defect filling (n = 6): Control Group
Ytalo Fernandes, Rafael Mantovani, Danilo Reino, Arthur Novaes, Michel Messora, Luiz Gustavo Sousa, Daniela Palioto, Sergio Scombatti de Souza   +7 more
doaj   +1 more source

Review of Bone Substitutes [PDF]

Craniomaxillofacial Trauma & Reconstruction, 2009
Bone substitutes are being increasingly used in craniofacial surgery and craniomaxillofacial trauma. We will review the history of the biomaterials and describe the ideal characteristics of bone substitutes, with a specific emphasis on craniofacial reconstruction.
Landon Pryor, Earl Gage, Claude-Jean Langevin, Fernando Herrera, Andrew Breithaupt, Chad Gordon, Ahmed Afifi, James Zins, Hal Meltzer, Amanda Gosman, Steve Cohen, Ralph Holmes   +11 more
openaire   +2 more sources