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Bone And Cartilage Tissue Engineering
Clinics in Plastic Surgery, 1999Tissue engineering of musculoskeletal tissues, particularly bone and cartilage, is a rapidly advancing field. In bone, technology has centered on bone graft substitute materials and the development of biodegradable scaffolds. Recently, tissue engineering strategies have included cell and gene therapy.
B D, Boyan +3 more
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Craniofacial bone tissue engineering
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2012There are numerous conditions, such as trauma, cancer, congenital malformations, and progressive deforming skeletal diseases, that can compromise the function and architectonics of bones of craniofacial region. The need to develop new approaches for treatment of these disorders arises from the fact that conventional therapeutic strategies face many ...
Vladimir, Petrovic +3 more
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An Overview of Tissue Engineered Bone
Clinical Orthopaedics and Related Research, 1999Numerous important developments in tissue engineering of new bone during the last 10 years are reviewed. Early efforts to combine cells with biocompatible materials are described and applications of this technology are presented with particular focus on uses in orthopaedics and maxillofacial surgery.
C A, Vacanti, L J, Bonassar
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Bone Marrow Tissue Engineering
Tissue Engineering, 2002The creation of mixed hematopoietic chimerism has become an important clinical strategy for tolerance induction for cellular and organ transplantation, and for the treatment of numerous hematopoietic diseases. Clinical success has been limited however, by host immune response and by competition from host hematopoiesis. Recent data suggests that limited
Alexander S, Krupnick +3 more
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Osteoblasts in bone tissue engineering
Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 2010Osteoblasts are integral to the development, growth, function, repair and maintenance of bone. The osteoblast forms organic, non-mineralized bone matrix and is involved in complex interactions with a variety of factors, mediators and cell types. Degeneration, pathology, and trauma cause disruption and destruction of the normal skeletal environment and ...
Jayakumar, P., Di Silvio, L.
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Electrospinning for Bone Tissue Engineering
Recent Patents on Nanotechnology, 2008Bone tissue engineering is a field of significant research interest owing to the large number of bone defects and the limitations in the present techniques to effectively reconstitute the defects. Cell-based bone graft technique has shown promise in overcoming the limitations of the other bone graft techniques currently used.
Koushik, Ramachandran +1 more
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Boning up on tissue engineering
Trends in Biotechnology, 2000The past two years have been an exciting time for the field of tissue engineering. There have been remarkable advances in eliciting the full developmental potential of stem cells from a number of mammalian tissues. In addition, the generation of human embryonic stem cell lines heralds a future in which a variety of tissues can be generated in culture ...
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Peptides for bone tissue engineering
Journal of Controlled Release, 2016Molecular signals in the form of growth factors are the main modulators of cell behavior. However, the use of growth factors in tissue engineering has several drawbacks, including their costs, difficult production, immunogenicity and short half-life. Furthermore, many of them are pleiotropic and, since a single growth factor can have different active ...
Rick, Visser +3 more
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Perspectives on Tissue Engineering of Bone
Clinical Orthopaedics and Related Research, 1999The normal repair and regeneration of bone occurs through an ordered and regulated sequence of cellular events. Successful replacement of bone through tissue engineering likely will be dependent on the recapitulation of this cascade of events. This report presents some of the principles to be considered in the design of engineered bone constructs.
S A, Goldstein, P V, Patil, M R, Moalli
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Craniofacial Bone Tissue Engineering
Dental Clinics of North America, 2006Repair and reconstruction of the craniofacial skeleton represents a significant biomedical burden, with thousands of procedures per-formed annually secondary to injuries and congenital malformations. Given the multitude of current approaches, the need for more effective strategies to repair these bone deficits is apparent.
Derrick C, Wan +2 more
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