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Bone tissue engineering

2022
Tissue engineering offers new treatments for disorders such as temporomandibular joint disorder which among others frequently afflicts patients. In this thesis, tissue engineering strategies are explored with an emphasis on addressing bone tissue repair.
Heather L. Ursino   +3 more
  +5 more sources

Tissue engineering of bone

Minimally Invasive Therapy & Allied Technologies, 2002
Despite well-established bone-grafting techniques, large bone defects still represent a challenge for orthopaedic and reconstructive surgeons. Efforts have therefore been made to develop osteoconductive, osteoinductive and osteogenic bone-replacement systems.
Kneser, Ulrich   +5 more
openaire   +3 more sources

Tissue-engineered bone regeneration

Nature Biotechnology, 2000
Bone lesions above a critical size become scarred rather than regenerated, leading to nonunion. We have attempted to obtain a greater degree of regeneration by using a resorbable scaffold with regeneration-competent cells to recreate an embryonic environment in injured adult tissues, and thus improve clinical outcome.
H, Petite   +8 more
openaire   +2 more sources

Bone Marrow Tissue Engineering

Tissue Engineering, 2002
The creation of mixed hematopoietic chimerism has become an important clinical strategy for tolerance induction for cellular and organ transplantation, and for the treatment of numerous hematopoietic diseases. Clinical success has been limited however, by host immune response and by competition from host hematopoiesis. Recent data suggests that limited
Alexander S, Krupnick   +3 more
openaire   +2 more sources

Craniofacial bone tissue engineering

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2012
There are numerous conditions, such as trauma, cancer, congenital malformations, and progressive deforming skeletal diseases, that can compromise the function and architectonics of bones of craniofacial region. The need to develop new approaches for treatment of these disorders arises from the fact that conventional therapeutic strategies face many ...
Vladimir, Petrovic   +3 more
openaire   +2 more sources

Craniofacial Bone Tissue Engineering

Dental Clinics of North America, 2006
Repair and reconstruction of the craniofacial skeleton represents a significant biomedical burden, with thousands of procedures per-formed annually secondary to injuries and congenital malformations. Given the multitude of current approaches, the need for more effective strategies to repair these bone deficits is apparent.
Derrick C, Wan   +2 more
openaire   +2 more sources

Bone Tissue Engineering

2014
The requirement for new bone to replace or restore the function of damaged or lost bone is a major clinical and social need. Bone tissue engineering has been considered as the alternative strategy to produce artificial bone grafts. The strategy of the method is to combine progenitor or mature cells isolated from desired cell source with biodegradable ...
HURİ, Pınar Yılgör   +2 more
openaire   +3 more sources

Bone Tissue Engineering

2010
Bone is a complex, living, constantly changing tissue. Bone consists of cancellous and cortical bone. This architecture allows the skeleton to perform its essential mechanical functions.
Reichert, Johannes, Hutmacher, Dietmar
openaire   +4 more sources

Bioreactors for Bone Tissue Engineering

The International Journal of Artificial Organs, 2011
Bone tissue engineering is a promising solution for patients with bone defects that require reconstruction. This regenerative therapy consists in culturing osteogenic cells on a biodegradable substrate to obtain a bio-hybrid construct that will stimulate bone healing after implantation.
Benoît, Carpentier   +2 more
openaire   +2 more sources

Osteoblasts in bone tissue engineering

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 2010
Osteoblasts are integral to the development, growth, function, repair and maintenance of bone. The osteoblast forms organic, non-mineralized bone matrix and is involved in complex interactions with a variety of factors, mediators and cell types. Degeneration, pathology, and trauma cause disruption and destruction of the normal skeletal environment and
Jayakumar, P., Di Silvio, L.
openaire   +3 more sources

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