Results 121 to 130 of about 241,658 (210)

Dnmt3a Mutations Limit Normal and Autoreactive CD4+ T Follicular Helper Responses and Attenuate T Cell–Driven Joint Inflammation

open access: yesArthritis &Rheumatology, EarlyView.
Objective Somatic DNMT3A mutations are the most common drivers of clonal hematopoiesis in patients with rheumatoid arthritis (RA) and have been associated with seropositive disease and increased markers of inflammation. These mutations are predominantly hypomorphic or dominant‐negative, reducing DNMT3A function.
Yunbing Shen   +10 more
wiley   +1 more source

All‐Inside, All‐Soft‐Tissue, Anchor‐Free Meniscal Allograft Transplantation

open access: yesArthroscopy Techniques, EarlyView.
Abstract Meniscal allograft transplantation is an effective surgical option for patients with irreparable meniscal pathology, including chronic root tears, complex or radial tears, and prior meniscectomy. This Technical Note describes an all‐inside, all‐soft‐tissue, anchor‐free arthroscopic technique for meniscal allograft transplantation designed to ...
Seksan Kukreja   +4 more
wiley   +1 more source

Arthroscopic Implantation of Minced Cartilage From the Os Trigonum and Posterolateral Process of the Talus: Single‐Stage Cell‐Based Treatment of Osteochondral Lesion of the Talus

open access: yesArthroscopy Techniques, EarlyView.
Abstract The best surgical treatment of osteochondral lesion of the talus (OLT) remains controversial. Among the available surgical procedures for OLTs, implantation of the minced cartilage from the talar lesion is a promising cell‐based technique. However, surgeons may experience difficulties when enough volume and quality of the cartilage cannot be ...
Hélder Pereira, Takuji Yokoe
wiley   +1 more source

Extracellular Matrix With Bone Marrow Aspirate Concentrate for Osteochondritis Dissecans of the Capitellum in Adolescents

open access: yesArthroscopy Techniques, EarlyView.
Abstract Capitellar osteochondritis dissecans is most frequently encountered in overhead and tumbling adolescent athletes. Traditional management with abrasion chondroplasty or microfracture results in fibrocartilage formation and variable return to sport rates, whereas osteochondral autograft transfer system or osteochondral allograft transplantation ...
Joshua T. Bram   +4 more
wiley   +1 more source

Algorithm-Based Surgical Decision-Making for Focal Knee Cartilage Defects: A Pragmatic Clinical Framework with Illustrative Cases. [PDF]

open access: yesOrthop Rev (Pavia)
Suiindik B   +5 more
europepmc   +1 more source

Dual‐Scaffold Technique: Autologous Minced Cartilage and Bone Marrow Aspirate Scaffold Combined With Synthetic Collagen Membrane for Cartilage Repair

open access: yesArthroscopy Techniques, EarlyView.
Abstract Treating cartilage injuries has long been a complex challenge; however, recent progress has greatly increased the variety of effective therapeutic approaches. The minced autologous matrix‐induced chondrogenesis plus procedure for full‐thickness knee cartilage lesions uses a collagen matrix combined with shaver‐minced cartilage graft and bone ...
Leonardo Ataíde   +5 more
wiley   +1 more source

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