Results 191 to 200 of about 445,769 (362)

Engineered Stem Cell Clusters for Extracellular Vesicles‐Mediated Gene Delivery to Rejuvenate Chondrocytes and Facilitate Chondrogenesis in Osteoarthritis Therapy

open access: yesAdvanced Science, EarlyView.
BMSCmotif+miR874/MS system is designed as a gene delivery platform utilizing engineered bone marrow mesenchymal stem cell (BMSC)‐derived extracellular vesicles (EVs) for intercellular communication to achieve sustained delivery of miRNA‐874‐3p. Rejuvenation of chondrocytes and promotion of chondrogenesis are achieved by inhibition of the NF‐κB pathway,
Yuezhou Wu   +7 more
wiley   +1 more source

Tailored 3D Lattice Microstructures for Enhanced Functionality in Blood‐Gas Exchange

open access: yesAdvanced Science, EarlyView.
Common hollow fiber structures are associated with inhomogeneous flow, leading to many complications in the medical application of extracorporeal membrane oxygenation. Using locally adapted lattice structures, the overall flow distribution can be manipulated.
Kai P. Barbian   +10 more
wiley   +1 more source

Minnesota acute graft-versus-host disease risk score predicts survival at onset of graft-versus-host disease after post-transplant cyclophosphamide prophylaxis

open access: yesHaematologica, 2022
Federica Ardizzoia   +16 more
doaj   +1 more source

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine

open access: yesAdvanced Science, EarlyView.
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang   +4 more
wiley   +1 more source

Reversal of Stress‐Induced PIEZO1 Elevation with Mechanically Adapted Epicardial Patch for Myocardial Infarction Treatment

open access: yesAdvanced Science, EarlyView.
This work identifies fine‐tuning the expression of PIEZO1 as a critical molecular mechanism underlying the treatment of myocardial infarction by mechanically adapted cardiac patches, which can support the clinical translation of cardiac patch devices.
Yuwen Lu   +18 more
wiley   +1 more source

The two-way paradigm of transplantation immunology [PDF]

open access: yes, 1996
Demetris, AJ   +7 more
core   +1 more source

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