BMSCmotif+miR874/MS system is designed as a gene delivery platform utilizing engineered bone marrow mesenchymal stem cell (BMSC)‐derived extracellular vesicles (EVs) for intercellular communication to achieve sustained delivery of miRNA‐874‐3p. Rejuvenation of chondrocytes and promotion of chondrogenesis are achieved by inhibition of the NF‐κB pathway,
Yuezhou Wu+7 more
wiley +1 more source
Transplantation tolerance, microchimerism, and the two-way paradigm [PDF]
Demetris, AJ, Starzl, TE
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Tailored 3D Lattice Microstructures for Enhanced Functionality in Blood‐Gas Exchange
Common hollow fiber structures are associated with inhomogeneous flow, leading to many complications in the medical application of extracorporeal membrane oxygenation. Using locally adapted lattice structures, the overall flow distribution can be manipulated.
Kai P. Barbian+10 more
wiley +1 more source
Clinical Report: Conference on Clinical Aspects of Radiation Injury and Transplantation of Bone Marrow and Other Organs [PDF]
C. Gordon Zubrod, Alexander Hollaender
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Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang+4 more
wiley +1 more source
Experimental and Clinical Study on the Bone Marrow Transplantation
T. Okano
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This work identifies fine‐tuning the expression of PIEZO1 as a critical molecular mechanism underlying the treatment of myocardial infarction by mechanically adapted cardiac patches, which can support the clinical translation of cardiac patch devices.
Yuwen Lu+18 more
wiley +1 more source
The two-way paradigm of transplantation immunology [PDF]
Demetris, AJ+7 more
core +1 more source
Biophysical Investigations of Bone Transplants and Bone Implants. An Experimental Study. By Kaj Holmstrand. 9 x 6 in. Pp. 66, with 34 figures and 2 tables. 1957. Copenhagen: Ejnar Munksgaard. Acta Orthopaedica Scandinavica, Supplement 26 [PDF]
H. A. Sissons
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