Results 191 to 200 of about 2,836,426 (349)

Elevator‐Like Hollow Channels in Porous Scaffolds Accelerate Vascularized Bone Regeneration via NETs‐Fibrin‐Mediated Macrophage Recruitment

Advanced Science, EarlyView.
This study demonstrates that how hollow‐channel scaffolds promote vascularized bone regeneration via an immunomodulatory mechanism. The channel structures facilitate the formation of a neutrophil extracellular traps‐fibrin scaffold that recruits vascular endothelial growth factor A (VEGF‐A)‐secreting M2 macrophages to drive angiogenesis. Combining this
Guifang Wang, Rongpu Liu, Huijing Ma, Shuhan Duan, Guangzheng Yang, LingXi Meng, Yuqin Qiao, Dongqiang Song, Wenjie Zhang   +8 more
wiley   +1 more source

Transgenic expression of hCD47 on pig cells provides only partial protection against human macrophage-mediated destruction in human immune system (HIS) mice. [PDF]

Am J Transplant
Mcheik S, Wang H, Ding X, Li HW, Sykes M.   +4 more
europepmc   +1 more source

Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization.

Circulation Research, 1999
T. Asahara, H. Masuda, Tomono Takahashi, C. Kalka, Christopher Pastore, Marcy Silver, Marianne Kearne, M. Magner, J. Isner   +8 more
semanticscholar   +1 more source

Mathematical Prediction for Geometry‐Mediated Cell 3D In‐Growth on Bone Tissue Engineering Scaffolds

Advanced Science, EarlyView.
This study identifies a fundamental pore size dependent pattern of three dimensional bone marrow derived mesenchymal stem cell (BMSC) infiltration within porous scaffolds, where small pores promote horizontal cellular bridging and large pores facilitate vertical migration.
Xiang Gao, Zhijun Yu, Yu Yan, Jiamin Ding, Wangsiyuan Teng, Chenhe Zhou, Minjun Yao, Wenkan Zhang, Shenzhi Zhao, Fangqian Wang, Zhenxuan Shao, Jinfeng Zhou, Xiaoyong Wu, Chengcheng Yu, Liang Chen, Xiaoqiang Jin   +15 more
wiley   +1 more source

Histological findings of the extraction socket (day 7). (A) Overview. (B) Control group, (C) transplanted group. The extraction sockets in both groups were filled with blood clots (arrows) and granulation tissue composed of inflammatory cells (neutrophils and macrophages) and fibroblasts (arrowheads). Moreover, new bone formation (*) was observed in the transplant group. Scale bars; (A) 300 µm (B, C) 200 µm.

Kohei Ijichi (21656230), Reiko Tokuyama-Toda (6744080), Mai Takeshita-Umehara (21656233), Toshio Yudo (21656236), Yusuke Takebe (6744074), Kazuhito Satomura (599629)   +5 more
openalex   +1 more source

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

Advanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen, Di Lu, Rukang Liang, Weikeng Tan, Erming Zhao, Sihuang Wu, Xintong Li, Yulong Song, Miaojian Wan, Xiaoyuan Xie, Qi Zhang, Qiuli Liu   +11 more
wiley   +1 more source

Clinical Insights into Mesenchymal Stem Cell Applications for Spinal Cord Injury. [PDF]

Int J Mol Sci
Shkap M, Namestnikova D, Cherkashova E, Chudakova D, Biktimirov A, Yarygin K, Baklaushev V.   +6 more
europepmc   +1 more source

A controlled trial of fluconazole to prevent fungal infections in patients undergoing bone marrow transplantation.

New England Journal of Medicine, 1992
J. Goodman, D. Winston, R. Greenfield, P. Chandrasekar, B. Fox, H. Kaizer, R. Shadduck, T. Shea, P. Stiff, D. J. Friedman, W. Powderly, J. Silber, H. Horowitz, A. Lichtin, S. Wolff, Mangan Kf, S. Silver, D. Weisdorf, W. Ho, G. Gilbert, D. Buell   +20 more
semanticscholar   +1 more source

Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles

Advanced Science, EarlyView.
A schematic diagram of the mechanism where small extracellular vesicles mediate the enhancement of heterotopic wound healing by radial extracorporeal shockwave stimulation at a proximal tibial osteotomy site. ABSTRACT Wound healing represents a complex biological process necessitating innovative therapeutic approaches, particularly for chronic wounds ...
Xiaoping Xie, Songqi Bi, Bang Su, Rongqi Zhou, Xudong Li, Zhixing Yan, Xiaoyang Zhou, Fanxu Wang, Tiecheng Yu   +8 more
wiley   +1 more source

Decision Analysis of Peripheral Blood versus Bone Marrow Hematopoietic Stem Cells for Allogeneic Hematopoietic Cell Transplantation [PDF]

, 2009
Joseph Pidala, Claudio Anasetti, Mohamed A. Kharfan‐Dabaja, Corey Cutler, Andy Sheldon, Benjamin Djulbegović   +5 more
openalex   +1 more source