Differentiation of metastatic lesions to the bones and multiple myeloma – a case study
Bones are one of the most common locations for cancer metastasis. Foci, which are in the most cases osteolytic, are located in the spine, ribs, pelvis, long bones.
Olaf Pachciński +5 more
doaj +1 more source
Liver transplantation in primary biliary cirrhosis: Risk assessment and 11-year follow-up [PDF]
Background/Aims: Liver transplantation (LTx) is the only established treatment in patients with end-stage primary biliary cirrhosis (PBC). Although short-term survival after LTx in this group of patients is usually good, few data exist on the long-term ...
Beuers, Ulrich +8 more
core +2 more sources
Background Classical MPNs including ET and PMF have a chronic course and potential for leukaemic transformation. Timely diagnosis is obligatory to ensure appropriate management and positive outcomes.
Uzma Zaidi +9 more
doaj +1 more source
Growth of donor-derived dendritic cells from the bone marrow of murine liver auograft recipients in response to granulocyte/macrophage colony-stimulating factor [PDF]
Allografts of the liver, which has a comparatively heavy leukocyte content compared with other vascularized organs, are accepted permanently across major histocompatibility complex barriers in many murine strain combinations without immunosuppressive ...
Fu, F +9 more
core +1 more source
Blastic plasmacytoid dendritic cell neoplasia - a rare type of acute leukemia
Neoplasmul cu celule dendritice plasmocitoide blastice (NCDPB), clasificat recent în grupul leucemiilor acute mieloide este o boală hematologică malignă rară cu evoluţie clinică extrem de agresivă.
Köpeczi Judit Beáta +5 more
doaj +1 more source
Long-term outcome after a treosulfan-based conditioning regimen for patients with acute myeloid leukemia: A report from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation [PDF]
BACKGROUND: Allogeneic hematopoietic cell transplantation (HCT) is a curative therapy for patients with acute myeloid leukemia (AML). However, post-HCT relapse and regimen-related toxicity remain significant barriers to long-term survival.
Al Mumma +41 more
core +1 more source
Bone marrow, or haematopoietic stem cell, transplants were originally developed to allow the use of very high dose treatments for malignancies such as leukaemia. Their use was based on the ideathat the high dose treatment might overcome inherent resistance of the malignancy to chemotherapy or radiotherapy. Transplants of stem cells from either the same
Johnson, Peter W. M., Orchard, Kim
openaire +3 more sources
Bone Marrow Failure as an Underrecognized Feature of KAT6A Syndrome
ABSTRACT KAT6A syndrome (Arboleda–Tham syndrome) is a rare disorder caused by heterozygous pathogenic variants in KAT6A, a histone acetyltransferase essential for chromatin remodeling and hematopoietic stem cell function. While neurodevelopmental features are well established, hematologic manifestations are underrecognized.
Ye Jee Shim +8 more
wiley +1 more source
Chronic myeloid leukemia (CML) is a clonal myeloproliferative disorder, which can involve the hematopoietic stem cell or early progenitor cells, without the loss of their capacity to differentiate.
Benedek István +6 more
doaj +1 more source
Pancreas and islet cell transplantation [PDF]
Currently, for the patient with type 1 diabetes, a definitive treatment without resorting to the use of exogenous insulin can be achieved only with pancreas or islet cell transplantation.
A.N. Balamurugan +94 more
core +1 more source

