Results 31 to 40 of about 2,993,509 (396)
BMC Cancer, 2020 Background Classical MPNs including ET and PMF have a chronic course and potential for leukaemic transformation. Timely diagnosis is obligatory to ensure appropriate management and positive outcomes.
Uzma Zaidi +9 more
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BMJ, 2002 Bone marrow, or haematopoietic stem cell, transplants were originally developed to allow the use of very high dose treatments for malignancies such as leukaemia. Their use was based on the ideathat the high dose treatment might overcome inherent resistance of the malignancy to chemotherapy or radiotherapy. Transplants of stem cells from either the same
Johnson, Peter W. M., Orchard, Kim
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Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Frontiers in Oncology, 2023 BackgroundPatients with refractory/relapsed (r/r) acute B lymphocytic leukemia (B-ALL) can achieve complete response (CR) after chimeric antigen receptor T-cell (CAR-T) therapy, but recurrence occurs in the short term.
Zhihui Li +11 more
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Human umbilical cord blood-borne fibroblasts contain marrow niche precursors that form a bone/marrow organoid in vivo [PDF]
, 2017 Human umbilical cord blood (CB) has attracted much attention as a reservoir for functional hematopoietic stem and progenitor cells, and, recently, as a source of blood-borne fibroblasts (CB-BFs). Previously, we demonstrated that bone marrow stromal cell (
Biondi, Andrea +11 more
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Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
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Advances in mesenchymal stem cell transplantation for the treatment of osteoporosis
Cell Proliferation, 2020 Osteoporosis is a systemic metabolic bone disease with characteristics of bone loss and microstructural degeneration. The personal and societal costs of osteoporosis are increasing year by year as the ageing of population, posing challenges to public ...
Yu-hua Jiang +4 more
semanticscholar +1 more source
OSTEOMYELITIS WITH BONE TRANSPLANTATION [PDF]
JAMA: The Journal of the American Medical Association, 1913 C. R., a French boy, 12 years old, living in Cambridge, was seen in consultation with Dr. H. C. Hache, Somerville, Mass. The patient had been sick for eleven days and had been seen by other physicians. Two months before he had received a cut in the right foot while skating, which had healed.
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Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li +12 more
wiley +1 more source