Results 51 to 60 of about 598,480 (360)

Risk and Prognostic Factors for Different Organ Metastasis in Primary Osteosarcoma: A Large Population‐Based Analysis

Orthopaedic Surgery, 2022
Objective Based on a large public cohort, we aimed to investigate the prevalence of distant metastases in patients with osteosarcoma, to evaluate the survival of patients with different metastases and to reveal the related risk and prognostic factors for
Guijun Xu, Haixiao Wu, Yanting Zhang, Yao Xu, Xu Guo, Vladimir P. Baklaushev, Vladimir P. Chekhonin, Karl Peltzer, Jun Wang, Feng Lu, Guowen Wang, Xin Wang, Wenjuan Ma, Chao Zhang   +13 more
doaj   +1 more source

Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles [PDF]

, 1996
Notch is a highly conserved transmembrane protein that is involved in cell fate decisions and is found in organisms ranging from Drosophila to humans. A human homologue of Notch, TAN1, was initially identified at the chromosomal breakpoint of a subset of
Aster, Jon C., Baltimore, David, Hasserjian, Robert P., Pear, Warren S., Scott, Martin L., Sklar, Jeffrey, Soffer, Benny   +6 more
core  

Osteoblastoma in the occipital bone: A case report of a rare tumor in the calvarium [PDF]

, 2020
Osteoblastomas infrequently occur in the calvarium, displaying a preference for temporal and frontal bones when it does. We present an unusual case of a large, expansile osteoblastoma in the occipital bone of a 23-year-old man who presented with a ...
Faro, Scott H., Gorniak, Richard J., Trunz, Lukas M.   +2 more
core   +2 more sources

The Efficacy and Safety of Bevacizumab/Irinotecan/Temozolomide (BIT) for Relapsed/Refractory Neuroblastoma: The UK Children's Cancer and Leukaemia Group Experience

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson, Menna Shamma, Upeka Senanayake, Shaimaa Sahmoud, Kathleen Duffin, Victoria Howard, David King, Ayesha Fathani, Blanche Lumb, Andrei Pobischan, Irum Latif Memon, Monzir Ahmed, Rhian Thomas, Gerard Millen, Yasmeen Alomari, Sucheta Vaidya, Lynley V. Marshall, Sally L. George, Ramya Ramanujachar, Juliet Gray, Paola Angelini   +20 more
wiley   +1 more source

Fluvastatin Prevents Lung Adenocarcinoma Bone Metastasis by Triggering Autophagy

EBioMedicine, 2017
Bone is one of the most preferred sites of metastasis in lung cancer. Currently, bisphosphonates and denosumab are major agents for controlling tumor-associated skeletal-related events (SREs).
Zuozhang Yang, Zhenyi Su, Judy Park DeWitt, Lin Xie, Yongbin Chen, Xiaojuan Li, Lei Han, Dongqi Li, Junfeng Xia, Ya Zhang, Yihao Yang, Congguo Jin, Jing Zhang, Su Li, Kun Li, Zhiping Zhang, Xin Qu, Zewei He, Yanjin Chen, Yan Shen, Mingyan Ren, Zhongqin Yuan   +21 more
doaj   +1 more source

Indirect induction of radiation lymphomas in mice. Evidence for a novel, transmissible leukemogen. [PDF]

, 1987
The transmission of a lymphomagenic agent(s) from the bone marrow of irradiated mice to thymic target cells has been demonstrated by: (a) the induction of T cell lymphomas in nonirradiated thymic grafts implanted in irradiated, Thy-l-congenic mice, (b ...
Hansteen, GA, Lieberman, M, McCune, JM, Scott, ML, Weissman, IL, White, JH   +5 more
core  

A potential role for Dkk-1 in the pathogenesis of osteosarcoma predicts novel diagnostic and treatment strategies. [PDF]

, 2007
Canonical Wnt signaling is an osteo-inductive signal that promotes bone repair through acceleration of osteogenic differentiation by progenitors. Dkk-1 is a secreted inhibitor of canonical Wnt signaling and thus inhibits osteogenesis.
Angela Smolarz, Carl Gregory, Darwin Prockop, Edwin Horwitz, Jacob Reiser, Najat Daw, Narae Lee, Odile David, Robert Kutner, Scott Olson   +9 more
core   +3 more sources

Alveolar Soft Part Sarcoma in Pediatric and Young Adult Patients: A Report From the Children's Oncology Group Study ARST0332

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Alveolar soft part sarcoma (ASPS) is a rare soft tissue sarcoma occurring most commonly in adolescence and young adulthood. Methods We present the clinical characteristics, treatments, and outcomes of patients with newly diagnosed ASPS enrolled on the Children's Oncology Group study ARST0332.
Jacquelyn N. Crane, Wei Xue, Amira Qumseya, Thomas Scharschmidt, Kathryn R. Tringale, Oscar Lopez Nunez, Jiaqi Hu, Donald A. Barkauskas, Rajkumar Venkatramani, Sheri L. Spunt, Aaron R. Weiss, Noah C. Federman   +11 more
wiley   +1 more source

The Prevalence and Associated Factors of Cancer Screening Uptake Among a National Population-Based Sample of Adults in Marshall Islands

Cancer Control, 2021
Background: The study aimed to estimate the prevalence and associated factors of cancer screening among men and women in the general population in Marshall Islands.
Supa Pengpid DrPh, Chao Zhang MD, Karl Peltzer PhD   +2 more
doaj   +1 more source

Clinical study of separation surgery combined with intraoperative vertebroplasty and 125I seeds implantation for spinal metastases from lung adenocarcinoma with epidural spinal cord compression

World Journal of Surgical Oncology
Background The study aim was to evaluate the efficacy and safety of separation surgery combined with intraoperative vertebroplasty and125I seeds implantation for the treatment of lung adenocarcinoma-associated metastatic epidural spinal cord compression (
Ya Zhang, Bin Fan, Tiying Wang, Yihao Yang, Nabil Zia UI Haq, Zhou Huang, Dachang Xu, Yan Liu, Dongqi Li, Lei Han, Weiquan Wang, Linhao Cai, Xiaohui Yang, Hongpu Sun, Jing Zhang, Cao Wang, Tao Yuan, Xiang Ma, Zuozhang Yang   +18 more
doaj   +1 more source