Results 111 to 120 of about 64,693 (183)

The cochlear morphometry compendium: High‐resolution synchrotron measurements and normative reference values

Journal of Anatomy, EarlyView.
In this study, 100 cadaveric temporal bones underwent synchrotron radiation phase‐contrast imaging. Images were segmented to produce 3D surface mesh models for morphological analysis. Measurements obtained for all cochleae included: standard gross dimensions, various cochlear lengths including basilar membrane length, detailed intracochlear scalar ...
Sumit K. Agrawal, Hao Li, Carmine Spedaliere, Helge Rask‐Andersen, Hanif M. Ladak   +4 more
wiley   +1 more source

Different level of intraspecific variation of the bony labyrinth morphology in slow- versus fast-moving primates

, 2016
International audienceThe vestibular system of the inner ear detects themotions of the head and is involved in maintaining balance.For this reason, this organ has been deeply studied and severalscientists have tried to link its morphology with the ...
Perier, Alexandre, Marivaux, Laurent, Lebrun, Renaud   +2 more
core   +1 more source

Periodontitis and Adverse Pregnancy Outcomes: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This narrative review aims to describe mechanisms linking periodontal diseases in pregnancy with adverse pregnancy outcomes. ABSTRACT Periodontal diseases, including both gingivitis and periodontitis, occur commonly among pregnant individuals. Both gingivitis and periodontitis are associated with adverse pregnancy outcomes (APOs) such as early ...
Gregory C. Valentine, Yiorgos A. Bobetsis, Benjamin C. Shayo, Peter Milgrom, Phoebus N. Madianos   +4 more
wiley   +1 more source

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

From mouth to brain: Linking periodontal and peri‐implant dysbiosis to systemic inflammation and neuropathology

Periodontology 2000, EarlyView.
Abstract Background/Aim Growing evidence suggests that imbalances occurring within the human microbiota and deregulation of the host immune response may play a significant role in the development of neurodegenerative diseases. Materials and Methods A comprehensive narrative review of the latest experimental, clinical, and epidemiological insights was ...
Emilio A. Cafferata, Frank Schwarz, Jaime Díaz‐Zúñiga, Alpdogan Kantarci   +3 more
wiley   +1 more source

Augustine Tower labyrinth

, 2018
St Augustine's Tower, Hackney. Creating and walking a cross-shaped 'stepping stone' temporary labyrinth on the footprint of a lost church.
Penfold, E., Overall, S.
core  

Circling behavior developed in Dmp1 null mice is due to bone defects in the vestibular apparatus

International Journal of Biological Sciences, 2010
With age, there is a progressive loss of body balance function. Yet, the potential influence of osteoporosis on body balance is largely unknown. Dentin matrix protein 1 (DMP1) is highly expressed in bone and required for phosphate homeostasis and ...
Kun Lv, Haiyang Huang, Yongbo Lu, Chunlin Qin, Zubing Li, Jian Q. Feng
doaj  

Targeted Degradation of STING by a Neutrophil Membrane‐Coated Nanoplatform Suppresses Microglial Pyroptosis After Subarachnoid Hemorrhage

Advanced Science, Volume 13, Issue 55, 5 October 2026.
MG1@NM‐Px serves as a microglia‐targeted STING‐degrading nanoplatform for subarachnoid hemorrhage. Following systemic administration, it crosses the blood–brain barrier and accumulates in activated microglia. STP1‐mediated STING ubiquitination and degradation suppress MAPK/inflammasome signaling, GSDME‐mediated pyroptosis, and IL‐1β release, revealing ...
Ruotian Zhang, Kaikun Yuan, Haoyu Zou, Hanfeng Qin, Jiale Liu, Jianda Sun, Feifan Zhang, Yuankui Wang, Tong Wang, Jiaxing Dai, Chunxu Li, Yichi Chen, Yingfeng Tu, Huaizhang Shi   +13 more
wiley   +1 more source

The angular trajectory of the vestibular aqueduct: evaluation using photon-counting CT

Insights into Imaging
The angular trajectory of the vestibular aqueduct (ATVA) has been proposed as a radiographic marker for developmental endotypes of Menière’s disease. Current ATVA measurements rely on software-based proxies because the proximal vestibular aqueduct is ...
Frederik Van den Kerkhof, Lukas Boomgaert, Lesley Cockmartin, Robert Hermans   +3 more
doaj   +1 more source

Explore the Mechanism of Xiaoyaosan for Treatment of Bipolar Disorder Based on Network Pharmacology, Experimental Validation and Molecular Docking

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
This study evaluates Xiaoyaosan (XYS) for bipolar disorder (BD) using network pharmacology and experimental validation. Molecular docking reveals interactions between active XYS compounds and potential core targets. Animal experiments confirm XYS alleviates BD‐like behaviors in mice by suppressing core targets, elucidating its multi‐target mechanism ...
Man Chen, Nana Ding, Xingmin Qiu, Lan Li, Yali Guo, Rongyanqi Wang, Xiaowei Mo, Tan Zou, Shangzhen Yu, Xiaojuan Li, Jiaxu Chen   +10 more
wiley   +1 more source