Results 61 to 70 of about 64,693 (183)

Leveraging Microphysiological Systems to Facilitate Neutrophil‐Based Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Microphysiological systems are emerging as powerful human‐relevant platforms for studying neutrophil biology in cancer. Current applications of spheroids, organoids, and organ‐on‐a‐chip models are reviewed, together with future opportunities in behaviorome profiling, multi‐omics integration, personalized medicine, immune crosstalk, and multi‐organ ...
Shuai Shao   +2 more
wiley   +1 more source

A virtual exploration of the lost labyrinth: developing a reconstructive model of Hawara Labyrinth pyramid complex [PDF]

open access: yes, 2000
This paper reports on a case study that explores the possibility of reproducing a destroyed historic site from its remaining artefacts. Using VR (virtual reality) technologies, we construct a series of low-end, 3D models that are navigable through the ...
Shiode, Narushige   +3 more
core  

Classification and Current Management of Inner Ear Malformations

open access: yesBalkan Medical Journal, 2017
Morphologically congenital sensorineural hearing loss can be investigated under two categories. Majority of the congenital hearing loss (80%) are membranous malformations. Here the pathology involves inner ear hair cells.
Levent Sennaroğlu, Münir Demir Bajin
doaj   +1 more source

The evolution of the vestibular apparatus in apes and humans

open access: yeseLife, 2020
Phylogenetic relationships among extinct hominoids (apes and humans) are controversial due to pervasive homoplasy and the incompleteness of the fossil record.
Alessandro Urciuoli   +6 more
doaj   +1 more source

Remote Ischemic Post‐Conditioning Preserves the Neurovascular Unit by Brain‐Derived Gas6 That Drives Monocyte‐Derived Macrophage Reprogramming via Axl and Vimentin after SAH

open access: yesAdvanced Science, EarlyView.
Subarachnoid hemorrhage (SAH) triggers monocyte‐derived macrophage (MDM) infiltration and M1‐like polarization via Vimentin upregulation, leading to neurovascular unit disruption and cognitive dysfunction. Remote ischemic postconditioning (RIPostC) upregulates neuronal Gas6, which activates Axl on MDMs to downregulate Vimentin and drive reparative M2 ...
Yajun Zhu   +14 more
wiley   +1 more source

MN•CS•IO System: Cross‐Species Study for HBB Function in High‐Altitude Hypoxia Adaptation

open access: yesAdvanced Science, EarlyView.
We developed an integrative mesh‐nanorod sorting, chitosan nanoparticle delivery, and intraosseous injection (MN•CS•IO) system to investigate HBB in high‐altitude hypoxia adaptation. Transplanting Tibetan animals' HBB‐modified Lin‐ cells into mice achieved 95.59% transfection efficiency and 8.15% HBB expression. High‐altitude HBB recipients upregulated
Wenqiao Hui   +18 more
wiley   +1 more source

A Neutrophil Membrane‐Encapsulated Pd/hCeO2 Nanoformulation for Alleviating Age‐Dependent Perioperative Neurocognitive Disorders

open access: yesAdvanced Science, EarlyView.
This study reports a neutrophil membrane‐encapsulated Pd/hCeO2 nanozyme (PCN) for targeted treatment of perioperative neurocognitive disorders (PND) in aged mice. PCN inhibits glycolysis‐driven microglial activation and neuroinflammation, improves mitochondrial respiration, and maintains blood‐brain barrier integrity and synaptic function, ultimately ...
Lili Huang   +17 more
wiley   +1 more source

Petrosal ofDasypus novemcinctus (TMM M-1885) within which sits endocast of bony labyrinth.

open access: yes, 2013
Each part of the figure are oriented the same with anterior towards top and medial towards left. A, tympanic view of petrosal bone; B, bone rendered semi-transparent to reveal bony labyrinth; C, endocast of bony labyrinth. Abbreviations listed at the end
Eric G. Ekdale (216740)
core   +1 more source

Scanning Electron Microscopy in the Evaluation of Defects to the Ossicular Chain in the Course of Chronic Otitis Media

open access: yesEar, Nose & Throat Journal, 2021
Objective: Chronic otitis media is a heterogeneous disorder. Chronic suppurative otitis media with cholesteatoma and, to a lesser extent, chronic otitis media with granulation lead to the destruction of bone structures within the middle ear.
Agnieszka Wiatr MD, PhD   +3 more
doaj   +1 more source

A Hypothalamic Oxytocinergic–Sympathetic Axis Couples Anxiety Dysregulation With Impaired Tendon–Bone Repair

open access: yesAdvanced Science, EarlyView.
RCI is associated with functional suppression of oxytocinergic neurons in the PVN. Reduced PVNOXT neuronal activity contributes to altered sympathetic regulation involving the IML–sympathetic chain pathway, accompanied by changes in norepinephrine signaling at the BTI.
Liyang Wan   +8 more
wiley   +1 more source

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