Results 151 to 160 of about 77,306 (289)

Program disclosure booklet and participation agreement. 2019: Jan. 31.

, 2007
Title from PDF title page (viewed Jan. 10, 2008).; "November 5, 2007."; Accompanied by "Supplement no. 1 dated November 5, 2007, to the Connecticut Higher Education Trust Program disclosure booklet dated November 5, 2007" (2 p. : digital, PDF file)
Connecticut Higher Education Trust.
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PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Adaptation of behavioural activation for adolescents with mild to moderate intellectual disabilities and depression. [PDF]

Front Psychiatry
Cameron LA, Melvin GA, Hastings RP, Paris A, Jahoda A, Meade A, Gray KM.   +6 more
europepmc   +1 more source

Booklet on sport fishing in Barcelos, Amazonas, Brazil user's views

The incredible beauty of the middle Negro River region in the Amazon,represented in the municipality of Barcelos, Amazonas, attracts many people wholove sport fishing.
Lubich, Chiara, Siqueira-Souza, Flávia, Bernardino, Glenda, Freitas, Carlos   +3 more
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Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Improving Resident Doctors' Preparedness for General Medical On-Call Shifts Through Structured Induction Resources: A Quality Improvement Project at a Large UK Teaching Hospital. [PDF]

Cureus
Brighton C, Anderson B.
europepmc   +1 more source

Booklet, You in Tokyo

, 1945
Nine-page booklet titled "You in Tokyo." Booklet was issued to civilian employees by the director of civilian personnel. The booklet details precautions, recreation, and everyday life for these employees. Nine pages, paper, ink.Robert Kiyoshi Midzuno was
U.S. Army
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In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Discharge after coronary artery bypass grafting: A qualitative study highlighting the need for individualised, person-centred care. [PDF]

PLoS One
Rushton M, Howarth M, Iles-Smith H.
europepmc   +1 more source

Nebraska Promotional Booklet

, 1897
Nebraska Promotional Booklet, 'Nebraska A Few Facts and Figures Concerning the Agricultural Resources of this State 1897.' Note: This booklet describes Nebraska agriculture and was designed to promote settlement and farming in Nebraska.

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