Results 161 to 170 of about 77,306 (289)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Animal-Assisted Psychoeducational Intervention in Paediatric Oncohaematology: Evidence from a Single-Centre Observational Study. [PDF]

Children (Basel)
Battaglini C, Isaja V, Riscossa G, Giordano M, Quarello P, Zucchetti G, Fagioli F.   +6 more
europepmc   +1 more source

Booklet, W.C.C.A. Center Stores

, 1941
Small blue booklet that used to house multiple stamps. Only one stamp found in it. Booklet reads, "The Coupons in this book are good for merchandise only at W.C.C.A. Center Stores" One booklet.
War Relocation Authority
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Performance of the Dutch Triage standard in managing fever in children in out-of-hours primary care: a secondary analysis of the chili study. [PDF]

Fam Pract
Gottwald RN, de Bont EGPM, Cals JWL, Wynants L.   +3 more
europepmc   +1 more source

Fundraiser Booklet

, 1961
Booklet put out by the Baton Rouge Little Theater organization to request donations and assistance in obtaining a new Baton Rouge Little Theatre venue.

core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Picturing better outcomes: Illustrated educational booklets improve patient-reported outcomes and reduce healthcare utilization in abdominal transplantation. [PDF]

World J Transplant
Di Napoli M, Kadri H, Kessler D, Canty G, Klingenberg K, Pomfret EA, Pomposelli JJ, Pshak T, Choudhury RA, Nydam TL, Baimas-George M.   +10 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source