Results 71 to 80 of about 36,568 (244)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Perubahan Pengetahuan dan Kepatuhan Minum Tablet Tambah Darah pada Ibu Hamil melalui Buklet Anemia
Journal of Health (JOH)Background: According to Riskesdas, the rate of anemia in pregnancy in Indonesia has increased by 11% from 2013, around 37.1% to 48.9% in 2018, but decreased by 21.2% in 2023.
Yunita Amraeni, Sri Mulyani
doaj +1 more source
PENGEMBANGAN BUKU SUPLEMEN PENDEKATAN MOLEKULAR TAKSONOMI HEWAN VERTEBRATA
Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan, 2016 Textbook is a book that is used to achieve the learning objectives in the learning activities. One type textbook is the supplements book. The supplements book have characteristics not integrated with the learning objectives directly, but the goal is to ...
Haqqi Anajili Setyanto +2 more
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Journal of Multidisciplinary Healthcare, 2023 Nutnichawan Muenchamnan,1 Warangkana Naksen,1 Parichat Ong-Artborirak1,2 1Faculty of Public Health, Chiang Mai University, Chiang Mai, Thailand; 2Department of Research and Medical Innovation, Faculty of Medicine Vajira Hospital, Navamindradhiraj ...
Muenchamnan N +2 more
doaj
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source