Results 51 to 60 of about 24,202 (263)

Complexity Lower Bound for Boolean Functions in the Class of Extended Operator Forms

open access: yesИзвестия Иркутского государственного университета: Серия "Математика", 2019
Starting with the fundamental work of D.E.Muller in 1954, the polynomial representations of Boolean functions are widely investigated in connection with the theory of coding and for the synthesis of circuits of digital devices.
A.S. Baliuk
doaj   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

open access: yesAdvanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao   +16 more
wiley   +1 more source

Logic‐Gated HSV‐TK/GCV Suicide Gene Circuit for Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
The BRAS comprises two modular genetic components driven by distinct tumor‐specific promoters and a failsafe layer with the NOT gate. This multi‐input logic gate circuit enables precise, specific expression of HSV‐TK in breast cancer cells with hardly expression in normal cell and effectively inhibits tumor growth in a triple‐negative breast cancer ...
Shasha Tang   +10 more
wiley   +1 more source

The Complexity of the Representation of Multiple-Output Boolean Functions

open access: yesИзвестия Иркутского государственного университета: Серия "Математика", 2016
This paper considers cost of logic circuits that implement Boolean functions. The realization of Boolean functions is considered in the class of reversible logic circuits.
S. Vinokurov, A. Frantseva
doaj  

Testing Boolean Function Isomorphism [PDF]

open access: yes, 2010
Two boolean functions f, g: {0, 1}n → {0, 1} are isomorphic if they are identical up to relabeling of the input variables. We consider the problem of testing whether two functions are isomorphic or far from being isomorphic with as few queries as possible.
Alon, Noga, Blais, Eric
openaire   +1 more source

High‐Fidelity Synthetic Data Replicates Clinical Prediction Performance in a Million‐Patient Diabetes Cohort

open access: yesAdvanced Science, EarlyView.
This study generates high‐fidelity synthetic longitudinal records for a million‐patient diabetes cohort, successfully replicating clinical predictive performance. However, deeper analysis reveals algorithmic biases and trajectory inconsistencies that escape standard quality metrics. These findings challenge current validation norms, demonstrating why a
Francisco Ortuño   +5 more
wiley   +1 more source

His‐MMDM: Multi‐Domain and Multi‐Omics Translation of Histopathological Images with Diffusion Models

open access: yesAdvanced Science, EarlyView.
His‐MMDM is a diffusion model‐based framework for scalable multi‐domain and multi‐omics translation of histopathological images, enabling tasks from virtual staining, cross‐tumor knowledge transfer, and omics‐guided image editing. ABSTRACT Generative AI (GenAI) has advanced computational pathology through various image translation models.
Zhongxiao Li   +13 more
wiley   +1 more source

Symmetry groups of boolean functions

open access: yesEuropean Journal of Combinatorics, 2014
We prove that every abelian permutation group, but known exceptions, is the symmetry group of a boolean function. This solves the problem posed in the book by Clote and Kranakis. In fact, our result is proved for a larger class of groups, namely, for all groups contained in direct sums of regular groups.
Grech, Mariusz, Kisielewicz, Andrzej
openaire   +3 more sources

Dynamic Decoration of DNA Scaffolds for High‐Resolution Cancer Cell Subtyping

open access: yesAdvanced Science, EarlyView.
This study presents a dual‐mode imaging platform that utilizes self‐assembly and disassembly of DNA scaffolds for high‐resolution cancer cell detection. The structural rigidity of DNA scaffolds effectively prevents cellular internalization for over 300 min.
Xiaolin Hu   +15 more
wiley   +1 more source

A Bottom‐Up Design Framework for Multifunctional Lattice Metamaterials

open access: yesAdvanced Science, EarlyView.
This study introduces a generative AI framework for designing multifunctional lattice metamaterials. The method combines 3D Gaussian voxel generation with deep learning, enabling greater design freedom and structural performance. The optimized lattice metamaterials achieve enhanced energy absorption by 40–200% compared to conventional structures and ...
Zongxin Hu   +13 more
wiley   +1 more source

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