Results 91 to 100 of about 11,341,390 (298)
scBoolSeq: Linking scRNA-seq statistics and Boolean dynamics.
PLoS Computational BiologyBoolean networks are largely employed to model the qualitative dynamics of cell fate processes by describing the change of binary activation states of genes and transcription factors with time.
Gustavo Magaña-López +3 more
doaj +1 more source
The spruce budworm and forest: a qualitative comparison of ODE and Boolean models
Letters in Biomathematics, 2016 Boolean and polynomial models of biological systems have emerged recently as viable companions to differential equations models. It is not immediately clear however whether such models are capable of capturing the multi-stable behaviour of certain ...
Raina Robeva, David Murrugarra
doaj +1 more source
Engineering CAR‐Macrophages With Advanced Delivery Systems for Tissue Repair
Advanced Science, EarlyView.This review highlights how engineered macrophages equipped with chimeric antigen receptors (CAR) guide tissue repair by recognizing disease‐related targets, clearing harmful cells, and reshaping local immune environments. It summarizes macrophage biology, CAR design, delivery platforms, and functionalization strategies, and discusses emerging ...
Yixin Zhang +8 more
wiley +1 more source
optPBN: an optimisation toolbox for probabilistic Boolean networks.
PLoS ONE, 2014 BackgroundThere exist several computational tools which allow for the optimisation and inference of biological networks using a Boolean formalism. Nevertheless, the results from such tools yield only limited quantitative insights into the complexity of ...
Panuwat Trairatphisan +4 more
doaj +1 more source
Frontiers in Physiology, 2020 The molecular regulatory network (MRN) within a cell determines cellular states and transitions between them. Thus, modeling of MRNs is crucial, but this usually requires extensive analysis of time-series measurements, which is extremely difficult to ...
Sang-Mok Choo +2 more
doaj +1 more source
A Cascaded DNA Nanocircuit for Multi‐Signal‐Responsive Precision siRNA Delivery in Cancer Therapy
Advanced Science, EarlyView.A cascaded dual‐AND logic DNA nanocircuit is engineered to respond to three tumor‐specific signals in a sequential manner: extracellular acidic pH, membrane‐overexpressed nucleolin (NCL), and intracellular glutathione (GSH). This programmable system selectively releases siPARP1 in glioblastoma (GBM), effectively silencing PARP1 and reversing TMZ ...
Yan Zhao +14 more
wiley +1 more source
A Novel SAT-Based Approach to the Task Graph Cost-Optimal Scheduling Problem [PDF]
, 2010 The Task Graph Cost-Optimal Scheduling Problem consists in scheduling a certain number of interdependent tasks onto a set of heterogeneous processors (characterized by idle and running rates per time unit), minimizing the cost of the entire process. This
Sergio Nocco +3 more
core +1 more source
Advanced Science, EarlyView.Electroforming‐free, self‐rectifying switching with polarity‐dependent threshold modulation is realized in selector‐only memory through Cu‐ion migration in a bilayer stacked dual functional materials. Ultrafast rupturing of Cu filament enables drift‐free operation with high stability.
Jae‐Kyeong Kim +7 more
wiley +1 more source
Xibei Gongye Daxue XuebaoExisting models for target detection on unmanned aerial vehicle platforms largely rely on the Boolean perception model. However, aiming at electromagnetic radiation sources, the Boolean perception model fails to accurately reflect the propagation and ...
DENG Wenjie +5 more
doaj +1 more source
Responsive Open Microfluidic Logic for Mechanical Computing
Advanced Science, EarlyView.Coupling elasticity with capillarity transforms mechanical compression into binary fluidic states, enabling deterministic logic in open microfluidic circuits. This work demonstrates that computation can emerge from interactions between mechanic and fluidic domains, establishing a general strategy for embedding information processing directly within ...
Roi Almog, Bat‐El Pinchasik
wiley +1 more source