Results 81 to 90 of about 14,077 (253)

Intraoperative Evaluation of Sarcoma Surgical Margins With Indocyanine Green Fluorescence Imaging: Results From an Observational Study

Journal of Surgical Oncology, EarlyView.
ABSTRACT Introduction Sarcomas are rare malignancies that affect both adults and children. Surgical removal with negative histopathological margins is the foundation of sarcoma treatment. Failure to achieve negative margins puts patients at risk of local recurrence (LR). LR rates range between 10% and 30%.
Sumail Bhogal, Matthew Gong, William Li, Brenda Diergaarde, Alma Heyl, Clark Roth, Lawrence Garvin II, Alexander Hoffman, Amanda Locker, Ines Lohse, Maria Silvaggio, Stella Lee, Richard McGough, Kurt Weiss   +13 more
wiley   +1 more source

Pelvic Exenteration for Cervical Cancer: Oncological, Morbidity and Quality of Life Outcomes

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives One third of patients who undergo definitive chemoradiotherapy for locally advanced cervical cancer develop disease recurrence. Salvage surgery in the form of pelvic exenteration (PE) may offer improved survival and possibly cure in carefully selected patients, however robust data is scarce.
Alexandra M. Peacock, Kilian G.M. Brown, Peter J. M. Lee, Kirk K. S. Austin, Christopher M. Byrne, Daniel Steffens, Michael J. Solomon   +6 more
wiley   +1 more source

From ACR O‐RADS 2022 to Explainable Deep Learning

Journal of Ultrasound in Medicine, EarlyView.
Objectives The 2022 update of the Ovarian‐Adnexal Reporting and Data System (O‐RADS) improves risk stratification of adnexal lesions; however, radiologist interpretation remains subject to inter‐observer variability and conservative diagnostic thresholds.
Ali Abbasian Ardakani, Afshin Mohammadi, Alisa Mohebbi, Anushya Vijayananthan, Sook Sam Leong, Yi Ting Lim, Mohd Kamil Bin Mohamad Fabell, Gernot Hudelist, Balint Balogh, Marlina Tanty Ramli Hamid, U Rajendra Acharya, Sepideh Hatamikia   +11 more
wiley   +1 more source

Pelvic Ultrasound for Predicting Endometrial Neoplasia in Premenopausal Abnormal Uterine Bleeding

Journal of Ultrasound in Medicine, EarlyView.
Objectives Although ultrasound is the first line imaging modality for abnormal uterine bleeding (AUB), there is a lack of consensus on its predictiveness for premenopausal endometrial pathology. This study aims to determine the predictiveness of pelvic ultrasound for endometrial neoplasia and cancer precursor lesions in premenopausal patients ...
Jessica Grubman, Delaina Bling, Haania Kakwan, Shubhangi Mehra, April Gorman, Alicia Kiszka, Diego H. Castrillon, Elysia Moschos   +7 more
wiley   +1 more source

WDR72 Drives Esophageal Squamous Cell Carcinoma Progression by Inhibiting Autophagy via the PI3K/Akt/mTOR Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Esophageal squamous cell carcinoma (ESCC) is an aggressive malignancy with a high rate of recurrence and metastasis, necessitating the identification of novel therapeutic targets. WD repeat‐containing protein 72 (WDR72) has been linked to various cancers, but its specific biological function and underlying mechanism in ESCC remain largely ...
Hao Wu, Zhong‐Xiang Jiang, Zheng Jiang
wiley   +1 more source

The Regulatory Role and Mechanism of Myoferlin in Mitophagy During Papillary Thyroid Carcinogenesis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Papillary thyroid carcinoma (PTC) is the most prevalent subtype of thyroid cancer; however, the regulatory mechanisms by which mitophagy influences its progression remain inadequately elucidated. This study sought to examine the role of myoferlin (MYOF) in mitophagy and its molecular basis during PTC development. Utilizing three paired PTC and
Wen‐Chao Lyu, Yang‐Shuai Wang, Chun‐Yang Shang, Ming Qi, Tong‐Chang Li, Li‐Xin Lian, Hai‐Quan Qiao   +6 more
wiley   +1 more source

Management tactics for patients suffering from borderline ovarian tumors in their reproductive years: in the wake of domestic and international guidelines

Клинический разбор в общей медицине
In recent decades, the attention of the medical community has increasingly focused on the problems associated with ovarian tumors, especially on the differentiation/difference between borderline tumors and ovarian cancer.
Vladlena M. Pernai, Marina V. Kiseleva, Mekan R. Orazov   +2 more
doaj   +1 more source

Borderline Ovarian Tumors [PDF]

Chettinad Health City Medical Journal, 2018
James May, Karolina Skorupskaite, Mario Congiu, Nidal Ghaoui, Graeme A. Walker, Scott Fegan, Cameron W. Martin, Rachel Louise O’Donnell   +7 more
openaire   +2 more sources

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Immunohistochemical Study of the CD44 Expression in Benign, Borderline and Malignant Surface Epithelial Ovarian Tumors and Metastatic Ovarian Tumors

Gynecology Obstetrics & Reproductive Medicine, 2007
OBJECTIVE: Carcinogenesis and metastasis are multistep processes involving complex interactions between tumor cells and the environment. The main cause of tumor cell movement in invasive carcinomas may be the loss of the intercellular adherence junction.
Gamze Yurdakan, Nilüfer Onak Kandemir, Sacide Çolak, Aylin Ege Gül, Nimet Karadayı, Şükrü Oğuz Özdamar   +5 more
doaj