Pharmacokinetics of Cephalexin after Intravenous and Single and Multiple Intramuscular Administration to Rabbit [PDF]
Cephalexin is a first generation cephalosporin widely used in rabbits. Its spectrum includes Pasteurella multocida and Staphylococcus aureus. These bacteria, together with Bordetella bronchiseptica, are the main cause of respiratory infections.
Albarellos, Gabriela Alejandra +2 more
core +2 more sources
Summary Two foals were being treated with a combination of oral doxycycline and rifampin for presumed Rhodococcus equi infections. After 3–4 weeks of antimicrobial administration, both foals presented with icterus and nonspecific clinical signs, including lethargy and inappetence.
A. Murdock +7 more
wiley +1 more source
Bordetella pertussis and Bordetella parapertussis: two immunologically distinct species [PDF]
Bordetella pertussis and Bordetella parapertussis are closely related species. Both are responsible for outbreaks of whooping cough in humans and produce similar virulence factors, with the exception of pertussis toxin, specific to B. pertussis. Current pertussis whole-cell vaccine will soon be replaced by acellular vaccines containing major adhesins ...
N, Khelef +3 more
openaire +2 more sources
Heat shock enhances outer-membrane vesicle release in Bordetella spp.
Pertussis, also known as whooping cough, is caused by the Gram-negative bacterium Bordetella pertussis, an obligate human pathogen. Despite high vaccination rates in high-income countries, resurgence of pertussis cases is an occurring problem that urges ...
Eline F. de Jonge +5 more
doaj +1 more source
Network model of immune responses reveals key effectors to single and co-infection dynamics by a respiratory bacterium and a gastrointestinal helminth [PDF]
Co-infections alter the host immune response but how the systemic and local processes at the site of infection interact is still unclear. The majority of studies on co-infections concentrate on one of the infecting species, an immune function or group of
A Graham +69 more
core +4 more sources
The Effect of Physical Disability on Employment
ABSTRACT The relationship between physical disability and employment is explored using microdata for older working‐age women in the 2016 Irish Census of Population and historical data on the incidence of infectious diseases. Two‐stage least squares and recursive bivariate probit estimations are employed to account for the potential endogeneity of ...
Irene Mosca
wiley +1 more source
A wolf in sheep's clothing: Dogs confer an unrecognized risk for their immunocompromised master
Bordetella bronchiseptica is a pleomorphic gram-negative coccobacillus that commonly causes respiratory tract infections in canines, felines, and swine. Human infections are rare.
Lipisha Agarwal +6 more
doaj +1 more source
Structural and functional specialization of Bordetella pertussis DsbA for pertussis toxin folding
Abstract Disulphide bonds (Dsbs) are essential for the folding, stability, and function of many secreted and membrane‐associated proteins in bacteria. In Gram‐negative species, these bonds are introduced by the Dsb enzyme family, with DsbA acting as the primary thiol oxidase.
Stephanie Penning +9 more
wiley +1 more source
Conversion of Bordetella pertussis to Bordetella parapertussis [PDF]
SUMMARYThe epidemiological and drug susceptibility data on whooping cough suggested a possibility that Bordetella pertussis converts in some way to Bordetella parapertussis. To prove this, B. pertussis strain 75 was treated with N-methyl-N'-nitro-N-nitrosoguanidine and a mutant resistant to staphcillin V and eight mutants resistant to trimethoprim were
N H, Kumazawa, M, Yoshikawa
openaire +2 more sources
Acellular pertussis vaccines protect against severe pertussis, but vaccine-induced immunity wanes over time. Prior animal studies showed that T-cell responses are integral to long-lasting immunity.
Muktha S. Natrajan +9 more
doaj +1 more source

