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Characterization of Post-Translational Modifications and Cytotoxic Properties of the Adenylate-Cyclase Hemolysin Produced by Various Bordetella pertussis and Bordetella parapertussis Isolates [PDF]

open access: yesToxins, 2017
Bordetella pertussis and Bordetella parapertussis are the causal agents of whooping cough in humans. They produce diverse virulence factors, including adenylate cyclase-hemolysin (AC-Hly), a secreted toxin of the repeat in toxins (RTX) family with ...
Thibaut Douché   +2 more
exaly   +4 more sources

Outer-Membrane-Vesicle–Associated O Antigen, a Crucial Component for Protecting Against Bordetella parapertussis Infection [PDF]

open access: yesFrontiers in Immunology, 2018
Bordetella parapertussis is a respiratory-disease pathogen producing symptomatology similar to that of pertussis but of underestimated incidence and with no specific vaccine existing. We recently designed a vaccine candidate from B.
Daniela Hozbor   +2 more
exaly   +4 more sources

Bordetella parapertussis Circumvents Neutrophil Extracellular Bactericidal Mechanisms. [PDF]

open access: yesPLoS ONE, 2017
B. parapertussis is a whooping cough etiological agent with the ability to evade the immune response induced by pertussis vaccines. We previously demonstrated that in the absence of opsonic antibodies B.
Juan Gorgojo   +4 more
doaj   +7 more sources

Molecular epidemiology and genomic features of Bordetella parapertussis in Shanghai, China, 2017–2022 [PDF]

open access: yesFrontiers in Microbiology
BackgroundPertussis is a highly contagious respiratory illness mainly caused by Bordetella pertussis (BP). Bordetella parapertussis (BPP) can induce symptoms compatible with pertussis, but has been underdiagnosed and underreported.
Chuanqing Wang   +2 more
exaly   +4 more sources

Melanin Produced by Bordetella parapertussis Confers a Survival Advantage to the Bacterium during Host Infection

open access: yesmSphere, 2021
In addition to the Gram-negative bacterium Bordetella pertussisBordetella ...
Yukihiro Hiramatsu   +4 more
doaj   +4 more sources

Pseudo-Outbreak of Bordetella parapertussis Caused by Contaminated Swabs in the Netherlands [PDF]

open access: yesEmerging Infectious Diseases, 2022
An increase in positive Bordetella parapertussis tests among patients in a teaching hospital in the Netherlands resulted in enhanced infection control and microbiological surveillance.
Jacky Flipse   +7 more
doaj   +2 more sources

Reemergence of Bordetella parapertussis, United States, 2019–2023 [PDF]

open access: yesEmerging Infectious Diseases
To determine changes in Bordetella pertussis and B. parapertussis detection rates, we analyzed 1.43 million respiratory multiplex PCR test results from US facilities from 2019 through mid-2023. From mid-2022 through mid-2023, Bordetella spp.
Brooklyn A. Noble   +3 more
doaj   +2 more sources

Pertussis Vaccines Scarcely Provide Protection against Bordetella parapertussis Infection in Children—A Systematic Review and Meta-Analysis [PDF]

open access: yesVaccines
Background: Pertussis, or whooping cough, is a global public health concern. Pertussis vaccines have demonstrated good protection against Bordetella pertussis infections, but their effectiveness against Bordetella parapertussis remains debated due to ...
Arun Thachappully Remesh   +4 more
doaj   +2 more sources

Multiplex real-time PCR assay for detection and differentiation of Bordetella pertussis and Bordetella parapertussis [PDF]

open access: yesIranian Journal of Microbiology, 2014
Background and Objective: Rapid diagnosis of pertussis is important for the timely isolation of the infection source and early prevention measures among the contact persons, especially among non-vaccinated infants for whom pertussis is life- threatening.
Valentina Kolodkina   +2 more
doaj   +1 more source

The type III secreted protein BspR regulates the virulence genes in Bordetella bronchiseptica. [PDF]

open access: yesPLoS ONE, 2012
Bordetella bronchiseptica is closely related with B. pertussis and B. parapertussis, the causative agents of whooping cough. These pathogenic species share a number of virulence genes, including the gene locus for the type III secretion system (T3SS ...
Jun Kurushima, Asaomi Kuwae, Akio Abe
doaj   +1 more source

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