Results 1 to 10 of about 4,701 (210)

Validation and Implementation of a Diagnostic Algorithm for DNA Detection of Bordetella pertussis, B. parapertussis, and B. holmesii in a Pediatric Referral Hospital in Barcelona, Spain. [PDF]

J Clin Microbiol, 2019
This study aimed to validate a comprehensive diagnostic protocolbased on real-time PCR for the rapid detection and identification ofBordetella per-tussis,Bordetella parapertussis, andBordetella holmesii, as well as its implementationin the diagnostic ...
Valero-Rello A, Henares D, Acosta L, Jane M, Jordan I, Godoy P, Muñoz-Almagro C.   +6 more
europepmc   +14 more sources

O antigen allows B. parapertussis to evade B. pertussis vaccine-induced immunity by blocking binding and functions of cross-reactive antibodies. [PDF]

PLoS ONE, 2009
Although the prevalence of Bordetella parapertussis varies dramatically among studies in different populations with different vaccination regimens, there is broad agreement that whooping cough vaccines, composed only of B.
Xuqing Zhang, Maria Eugenia Rodríguez, Eric T Harvill   +2 more
doaj   +8 more sources

Outer-Membrane-Vesicle–Associated O Antigen, a Crucial Component for Protecting Against Bordetella parapertussis Infection [PDF]

Frontiers in Immunology, 2018
Bordetella parapertussis is a respiratory-disease pathogen producing symptomatology similar to that of pertussis but of underestimated incidence and with no specific vaccine existing. We recently designed a vaccine candidate from B.
Daniela Bottero, María Eugenia Zurita, María Emilia Gaillard, Francisco Carriquiriborde, Pablo Martin Aispuro, Maia Elizagaray, Erika Bartel, Celina Castuma, Daniela Hozbor   +8 more
doaj   +7 more sources

The Eukaryotic Host Factor 14-3-3 Inactivates Adenylate Cyclase Toxins of Bordetella bronchiseptica and B. parapertussis, but Not B. pertussis [PDF]

mBio, 2018
Bordetella pertussis, Bordetella bronchiseptica, and Bordetella parapertussis share highly homologous virulence factors and commonly cause respiratory infections in mammals; however, their host specificities and disease severities differ, and the reasons
Aya Fukui-Miyazaki, Hirono Toshima, Yukihiro Hiramatsu, Keisuke Okada, Keiji Nakamura, Keisuke Ishigaki, Naoaki Shinzawa, Hiroyuki Abe, Yasuhiko Horiguchi   +8 more
doaj   +5 more sources

Reemergence of Bordetella parapertussis, United States, 2019–2023 [PDF]

Emerging Infectious Diseases
To determine changes in Bordetella pertussis and B. parapertussis detection rates, we analyzed 1.43 million respiratory multiplex PCR test results from US facilities from 2019 through mid-2023. From mid-2022 through mid-2023, Bordetella spp.
Brooklyn A. Noble, Sarah S. Jiudice, Jay D. Jones, Tristan T. Timbrook   +3 more
doaj   +2 more sources

Case Report: Possible C3 nephritic factor–driven complement-mediated severe hemolytic anemia and acute kidney injury in a child with Bordetella parapertussis infection [PDF]

Frontiers in Immunology
Overactivation of the complement system can cause life-threatening intravascular hemolysis, acute kidney injury (AKI), and multi-organ failure. Expanding the spectrum of rarer triggers of complement dysregulation that may cause severe hemolysis is ...
Steffen Ullitz Thorsen, Anne Todsen Hansen, Hans Jakob Hartling, Hanne Vibeke Marquart, Hanne Vibeke Marquart, Line Borgwardt, Mira Marie Laustsen, Lillemor Skattum, Lillemor Skattum, Alex Christian Yde Nielsen, Line Thousig Sehested, Hanne Nørgaard, Morten Hanefeld Dziegiel, Morten Hanefeld Dziegiel, Ida Maria Schmidt   +14 more
doaj   +2 more sources

Pertussis Vaccines Scarcely Provide Protection against Bordetella parapertussis Infection in Children—A Systematic Review and Meta-Analysis [PDF]

Vaccines
Background: Pertussis, or whooping cough, is a global public health concern. Pertussis vaccines have demonstrated good protection against Bordetella pertussis infections, but their effectiveness against Bordetella parapertussis remains debated due to ...
Arun Thachappully Remesh, Kalichamy Alagarasu, Santoshkumar Jadhav, Meera Prabhakar, Rajlakshmi Viswanathan   +4 more
doaj   +2 more sources

Comparison of Bordetella species identification among differing rt-PCR assays in the United States [PDF]

Microbiology Spectrum
In the United States, the general laboratory method for diagnosing pertussis, caused by Bordetella pertussis, is real-time PCR (rt-PCR) targeting insertion sequence 481 (IS481).
Matthew Cole, Ashley K. Simon, Amanda Faulkner, Tami Skoff, Maria L. Tondella, Clemente Montero, Melinda B. Nye, Margaret Williams   +7 more
doaj   +2 more sources

Diversity of Rhinovirus and Enterovirus Infections Among Pediatric Patients Hospitalized in Wisconsin, 2022-2023. [PDF]

J Med Virol
ABSTRACT Severe rhinovirus (RV)/enterovirus (EV) respiratory infections in pediatric patients increased in the US during 2022–2023. This study aimed to characterize RV/EV genetic diversity among hospitalized children in Wisconsin and describe demographic and clinical factors of patients by RV/EV type.
Litwak HL, Perez CM, Bateman A, Anhalt K, Lu X, Rogers S, Emery B, Ng TFF, Cubenas C, Gregory CO, Paden C, Haupt T, Kirking HL, Segaloff HE.   +13 more
europepmc   +2 more sources

From Lake Victoria to the Tap: Antibiotic Resistance and Pathogenic Contamination of Kisumu City Water Supply and Wastewater Network. [PDF]

Trop Med Int Health
ABSTRACT Waterborne diseases and antimicrobial resistance (AMR) pose mounting public health threats across sub‐Saharan Africa, particularly in rapidly urbanising regions dependent on untreated or poorly treated surface waters. This study applied shotgun metagenomic sequencing to characterise microbial communities, virulence factors and antibiotic ...
Reva ON, Sifuna A, Orata F, Omolo C, Iramiot JS, Enright MC, Mutshembele A, Zhou J, Shivoga WA.   +8 more
europepmc   +2 more sources