The recognition of bacterial lipopolysaccharide (LPS) by host Toll-like receptor (TLR)4 is a crucial step in developing protective immunity against several gram negative bacterial pathogens. Bordetella bronchiseptica and B.
Daniel N Wolfe +2 more
doaj +2 more sources
Outer-Membrane-Vesicle–Associated O Antigen, a Crucial Component for Protecting Against Bordetella parapertussis Infection [PDF]
Bordetella parapertussis is a respiratory-disease pathogen producing symptomatology similar to that of pertussis but of underestimated incidence and with no specific vaccine existing. We recently designed a vaccine candidate from B.
Daniela Bottero +8 more
doaj +2 more sources
Prevalence of Bordetella pertussis and Bordetella parapertussis in Samples Submitted for RSV Screening [PDF]
BACKGROUND: The clinical presentation of Bordetella pertussis can overlap with that of respiratory syncytial virus (RSV); however, management differs.HYPOTHESIS: First, the prevalence of B.
Walsh, Paul +5 more
doaj +3 more sources
T- and B-cell-mediated protection induced by novel, live attenuated pertussis vaccine in mice. Cross protection against parapertussis. [PDF]
BACKGROUND: Despite the extensive use of efficacious vaccines, pertussis still ranks among the major causes of childhood mortality worldwide. Two types of pertussis vaccines are currently available, whole-cell, and the more recent acellular vaccines ...
Pascal Feunou Feunou +2 more
doaj +1 more source
Suspected Macrolide-Refractory <i>Mycoplasma pneumoniae</i> Pneumonia With Discordant <i>Coccidioides</i> Serology in an Immunocompromised Host: A Case Report. [PDF]
Suspected macrolide‐refractory Mycoplasma pneumoniae pneumonia can be a diagnostic challenge in immunocompromised hosts, particularly after allogeneic stem cell transplantation. Screening serologies may further complicate diagnosis when false‐positive or discordant results divert therapy.
Mohamed MMG +5 more
europepmc +2 more sources
Intracellular trafficking of B. parapertussis.
Seven-day-old polarized monolayers were infected with B. parapertussis (MOI 20) for 5 h at 37°C, washed to remove non-attached bacteria, treated with polymyxin B (100 μg/ml) for 1 h at 37°C, washed, and incubated at 37°C in the presence of polymyxin B (5
Juan Pablo Gorgojo (17457568) +5 more
core +1 more source
Differential expression of alpha 4 integrins on effector memory T helper cells during Bordetella infections. Delayed responses in Bordetella pertussis. [PDF]
Bordetella pertussis (B. pertussis) is the causative agent of whooping cough, a respiratory disease that is reemerging worldwide. Mechanisms of selective lymphocyte trafficking to the airways are likely to be critical in the immune response to this ...
Tuan M Nguyen +9 more
doaj +1 more source
Bordetella pertussis and Bordetella parapertussis are the causal agents of whooping cough in humans. They produce diverse virulence factors, including adenylate cyclase-hemolysin (AC-Hly), a secreted toxin of the repeat in toxins (RTX) family with ...
Valérie Bouchez +6 more
doaj +1 more source
Bordetella pertussis, B. bronchiseptica, B. parapertussis(hu), and B. parapertussis(ov) are closely related respiratory pathogens that infect mammalian species. B. pertussis and B.
Dimitri A Diavatopoulos +5 more
doaj +2 more sources
The type III secreted protein BspR regulates the virulence genes in Bordetella bronchiseptica. [PDF]
Bordetella bronchiseptica is closely related with B. pertussis and B. parapertussis, the causative agents of whooping cough. These pathogenic species share a number of virulence genes, including the gene locus for the type III secretion system (T3SS ...
Jun Kurushima, Asaomi Kuwae, Akio Abe
doaj +1 more source

