Multiplex real-time PCR assay for detection and differentiation of Bordetella pertussis and Bordetella parapertussis [PDF]
Background and Objective: Rapid diagnosis of pertussis is important for the timely isolation of the infection source and early prevention measures among the contact persons, especially among non-vaccinated infants for whom pertussis is life- threatening.
Valentina Kolodkina +2 more
doaj +1 more source
Bordetella parapertussis Bacteremia: Clinical Expression and Bacterial Genomics. [PDF]
Whooping cough's primary etiological agent is Bordetella pertussis. The closely related Bordetella parapertussis rarely causes severe disease. Here we report an unusual case of bacteremia caused by B. parapertussis, review the literature, and characterize the genomic sequence of the bacterial isolate in comparison with B.
Toubiana J +7 more
europepmc +5 more sources
Complete Structures of Bordetella bronchiseptica and Bordetella parapertussis Lipopolysaccharides [PDF]
The structures of the lipopolysaccharide (LPS) core and O antigen of Bordetella bronchiseptica and Bordetella parapertussis are known, but how these two regions are linked to each other had not been determined. We have studied LPS from several strains of these microorganisms to determine the complete carbohydrate structure of the LPS.
Preston, A +6 more
openaire +5 more sources
Conversion of Bordetella pertussis to Bordetella parapertussis [PDF]
SUMMARYThe epidemiological and drug susceptibility data on whooping cough suggested a possibility that Bordetella pertussis converts in some way to Bordetella parapertussis. To prove this, B. pertussis strain 75 was treated with N-methyl-N'-nitro-N-nitrosoguanidine and a mutant resistant to staphcillin V and eight mutants resistant to trimethoprim were
N H, Kumazawa, M, Yoshikawa
openaire +2 more sources
Bordetella pertussis and Bordetella parapertussis: two immunologically distinct species [PDF]
Bordetella pertussis and Bordetella parapertussis are closely related species. Both are responsible for outbreaks of whooping cough in humans and produce similar virulence factors, with the exception of pertussis toxin, specific to B. pertussis. Current pertussis whole-cell vaccine will soon be replaced by acellular vaccines containing major adhesins ...
N, Khelef +3 more
openaire +2 more sources
The type III secreted protein BspR regulates the virulence genes in Bordetella bronchiseptica. [PDF]
Bordetella bronchiseptica is closely related with B. pertussis and B. parapertussis, the causative agents of whooping cough. These pathogenic species share a number of virulence genes, including the gene locus for the type III secretion system (T3SS ...
Jun Kurushima, Asaomi Kuwae, Akio Abe
doaj +1 more source
T- and B-cell-mediated protection induced by novel, live attenuated pertussis vaccine in mice. Cross protection against parapertussis. [PDF]
BACKGROUND: Despite the extensive use of efficacious vaccines, pertussis still ranks among the major causes of childhood mortality worldwide. Two types of pertussis vaccines are currently available, whole-cell, and the more recent acellular vaccines ...
Pascal Feunou Feunou +2 more
doaj +1 more source
Bordetella pertussis, Bordetella bronchiseptica, and Bordetella parapertussis share highly homologous virulence factors and commonly cause respiratory infections in mammals; however, their host specificities and disease severities differ, and the reasons
Aya Fukui-Miyazaki +8 more
doaj +1 more source
Multicenter Evaluation of the QIAstat-Dx Respiratory Panel for the Detection of Viruses and Bacteria in Nasopharyngeal Swab Specimens [PDF]
The QIAstat-Dx Respiratory Panel (QIAstat-Dx RP) is a multiplex in vitro diagnostic test for the qualitative detection of 20 pathogens directly from nasopharyngeal swab (NPS) specimens. The assay is performed using a simple sample-to-answer platform with
Granato, Paul +8 more
core +1 more source
Improving specificity of Bordetella pertussis detection using a four target real-time PCR. [PDF]
The incidence of whooping cough, a contagious respiratory disease caused by Bordetella pertussis, is on the rise despite existing vaccination programmes.
Helena Martini +4 more
doaj +1 more source

