Results 41 to 50 of about 4,734 (199)

Pertussis among patients with clinically compatible illness in the Amhara Regional State, Ethiopia

open access: yesInternational Journal of Infectious Diseases, 2021
Background: Pertussis is an acute respiratory tract disease caused by Bordetella pertussis. In 2014, 24.1 million pertussis cases, resulting in 160,700 deaths, were estimated to have occurred worldwide.
Solomon Taye   +8 more
doaj   +1 more source

Outer membrane vesicles derived from Bordetella parapertussis as an acellular vaccine against Bordetella parapertussis and Bordetella pertussis infection

open access: yesVaccine, 2013
Bordetella parapertussis, a close related species of B. pertussis, can also cause the disease named pertussis or whooping cough. The number of cases caused by this related pathogen has risen sustained in the last years. The widely used cellular (wP) or acellular (aP) pertussis vaccines have little or no efficacy against B. parapertussis.
Bottero, Daniela   +7 more
openaire   +3 more sources

A real-time PCR assay with improved specificity for detection and discrimination of all clinically relevant Bordetella species by the presence and distribution of three Insertion Sequence elements

open access: yesBMC Research Notes, 2011
Background In Dutch laboratories molecular detection of B. pertussis and B. parapertussis is commonly based on insertion sequences IS481 and IS1001, respectively. Both IS elements are more widely spread among Bordetella species. Both Bordetella holmesii,
Ossewaarde Jacobus M   +3 more
doaj   +1 more source

Bbvac: A Live Vaccine Candidate That Provides Long-Lasting Anamnestic and Th17-Mediated Immunity against the Three Classical Bordetella spp.

open access: yesmSphere, 2022
Acute pathogens such as Bordetella pertussis can cause severe disease but are ultimately cleared by the immune response. This has led to the accepted paradigm that convalescent immunity is optimal and therefore broadly accepted as the “gold standard ...
Monica C. Gestal   +3 more
doaj   +1 more source

Role of phosphoglucomutase of Bordetella bronchiseptica in lipopolysaccharide biosynthesis and virulence [PDF]

open access: yes, 2000
The phosphoglucomutase (PGM)-encoding gene of Bordetella bronchiseptica is required for lipopolysaccharide (LPS) biosynthesis. An insertion mutant of the wild-type B.
West, Nicholas P.   +5 more
core   +1 more source

Phylogenetic analysis reveals an ancient gene duplication as the origin of the MdtABC efflux pump. [PDF]

open access: yes, 2020
The efflux pumps from the Resistance-Nodulation-Division family, RND, are main contributors to intrinsic antibiotic resistance in Gram-negative bacteria. Among this family, the MdtABC pump is unusual by having two inner membrane components.
Górecki, Kamil, McEvoy, Megan M
core   +2 more sources

In vitro susceptibilities of Bordetella pertussis and Bordetella parapertussis to seven fluoroquinolones [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 1990
The in vitro susceptibilities of Bordetella pertussis and Bordetella parapertussis to seven fluoroquinolones were assessed by the agar dilution method. Ciprofloxacin and temafloxacin were the most active compounds (MIC for 90% of isolates tested [MIC90], 0.06 microgram/ml), while enoxacin and pefloxacin were the least active (MIC90, 0.5 microgram/ml ...
J E, Hoppe, C G, Simon
openaire   +2 more sources

Pathogenicity and virulence of Bordetella pertussis and its adaptation to its strictly human host

open access: yesVirulence, 2021
The highly contagious whooping cough agent Bordetella pertussis has evolved as a human-restricted pathogen from a progenitor which also gave rise to Bordetella parapertussis and Bordetella bronchiseptica.
Thomas Belcher   +4 more
doaj   +1 more source

Natural History and Ecology of Interactions Between Bordetella Species and Amoeba

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
A variety of bacteria have evolved the ability to interact with environmental phagocytic predators such as amoebae, which may have facilitated their subsequent interactions with phagocytes in animal hosts.
Longhuan Ma   +6 more
doaj   +1 more source

Antibiotics in acute bronchitis: a meta-analysis. [PDF]

open access: yes, 1999
PurposeMost patients with acute bronchitis who seek medical care are treated with antibiotics, although the effectiveness of this intervention is uncertain.
Bent, S   +3 more
core   +1 more source

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