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Immunomodulation as a Novel Strategy for Prevention and Treatment of Bordetella spp. Infections [PDF]

Frontiers in Immunology, 2019
Well-adapted pathogens have evolved to survive the many challenges of a robust immune response. Defending against all host antimicrobials simultaneously would be exceedingly difficult, if not impossible, so many co-evolved organisms utilize ...
Monica C. Gestal, Hannah M. Johnson, Eric T. Harvill   +2 more
doaj   +3 more sources

Cytokine expression patterns in hospitalized children with Bordetella pertussis, Rhinovirus or co-infection

Scientific Reports, 2021
Mechanisms of interaction between Bordetella pertussis and other viral agents are yet to be fully explored. We studied the inflammatory cytokine expression patterns among children with both viral-bacterial infections.
Elisabetta Pandolfi, Nadia Panera, Anna Alisi, Emanuela Carloni, Luisa Russo, Ilaria Campagna, Caterina Rizzo, Carlo Concato, Giulia Linardos, Livia Piccioni, Sally Jackson, Alberto Villani, Fabio Midulla, Alberto E. Tozzi   +13 more
doaj   +2 more sources

Comparative Phosphoproteomics of Classical Bordetellae Elucidates the Potential Role of Serine, Threonine and Tyrosine Phosphorylation in Bordetella Biology and Virulence

Frontiers in Cellular and Infection Microbiology, 2021
The Bordetella genus is divided into two groups: classical and non-classical. Bordetella pertussis, Bordetella bronchiseptica and Bordetella parapertussis are known as classical bordetellae, a group of important human pathogens causing whooping cough or ...
Laurence Don Wai Luu, Ling Zhong, Sandeep Kaur, Mark J. Raftery, Ruiting Lan   +4 more
doaj   +2 more sources

Cystic Fibrosis Mice Develop Spontaneous Chronic Bordetella Airway Infections

Journal of Infectious Pulmonary Diseases, 2017
Chronic pulmonary disease and infection is the primary cause of morbidity and mortality in people with cystic fibrosis (CF). Though Pseudomonas aeruginosa, is most commonly found in the airways of individuals with CF, there is increasing appreciation for
Rebecca Darrah, Tracey L. Bonfield, John J. LiPuma, Paul Litman, Craig A. Hodges, Frank J. Jacono, Mitchell L. Drumm   +6 more
openalex   +2 more sources

Bordetella pertussis: an underreported pathogen in pediatric respiratory infections, a prospective cohort study [PDF]

BMC Infectious Diseases, 2014
BackgroundThe incidence of pertussis has been increasing worldwide. In the Netherlands, the seroprevalence has risen higher than the reported cases, suggesting that laboratory tests for pertussis are considered infrequently and that even more pertussis ...
Gertrude van den Brink, Jérôme O. Wishaupt, Jacob C. Douma, Nico G. Hartwig, F. G. A. Versteegh   +4 more
openalex   +2 more sources

Bordetella hinzii Pneumonia and Bacteremia in a Patient with SARS-CoV-2 Infection

Emerging Infectious Diseases, 2021
Patients with severe acute respiratory syndrome coronavirus 2 infection may have bacterial co-infections, including pneumonia and bacteremia. Bordetella hinzii infections are rare, may be associated with exposure to poultry, and have been reported mostly
Michele Maison-Fomotar, Geetha Sivasubramanian   +1 more
doaj   +2 more sources

The Bordetella type III secretion system effector BteA targets host eosinophil-epithelial signaling to promote IL-1Ra expression and persistence [PDF]

Communications Biology
Eosinophils are traditionally associated with parasitic infections and allergic pathologies. However, emerging evidence highlights their underappreciated roles during mucosal bacterial infections.
Katelyn M. Parrish, Nicholas First, Jana Kamanova, Tyler L. Williams, Sarah Johnson, Jaylyn King, Karen M. Scanlon, Nurit P. Azouz, Seema Mattoo, Ciaran Skerry, Monica C. Gestal   +10 more
doaj   +2 more sources

Human infections associated with Bordetella bronchiseptica [PDF]

Clinical Microbiology Reviews, 1991
This study examines the potential of Bordetella bronchiseptica to act as a human pathogen. After encountering two patients from whom B. bronchiseptica was isolated, we searched the literature and found 23 reports in which a human infection was reported in association with B. bronchiseptica.
B F, Woolfrey, J A, Moody
openaire   +3 more sources

Bordetella holmesii in Nasopharyngeal Samples from Chilean Patients with Suspected Bordetella pertussis Infection [PDF]

Journal of Clinical Microbiology, 2012
We read the article of Njamkepo et al. ([5][1]) with great interest. These authors report the finding of Bordetella holmesii DNA in 177 IS 481 -positive nasopharyngeal samples from French patients with suspected pertussis.
Carolina, Miranda, Lorena, Porte, Patricia, García   +2 more
openaire   +4 more sources

Emergence of Bordetella holmesii–Associated Pertussis-Like Illness, Northern India, 2019–2023 [PDF]

Emerging Infectious Diseases
We investigated Bordetella holmesii and Bordetella pertussis in 935 suspected pertussis cases in northern India (2019–2023) using PCR and serology. B. holmesii showed increased prevalence in pertussis cases, particularly in older children, highlighting ...
Nishant Shekhar, Deepa Sharma, Surajit Chakraborty, Rajesh Kumar, Rajneesh Singh Rawat, Nirmal Kaundal, Pawan Kumar, Tigran Avagyan, Deeksha Chauhan, Neha Jain, Megha Sharma, Arun Kumar, Vikas Gautam   +12 more
doaj   +2 more sources