Bordetella pertussis pertactin knock-out strains reveal immunomodulatory properties of this virulence factor. [PDF]
Whooping cough, caused by Bordetella pertussis, has resurged and presents a global health burden worldwide. B. pertussis strains unable to produce the acellular pertussis vaccine component pertactin (Prn), have been emerging and in some countries ...
Hamstra, Hendrik-Jan +9 more
core +10 more sources
Introduction Bordetella bronchiseptica can be a cause of virulent pneumonia in humans with impaired immune systems. Few cases have been reported in the medical literature where Bordetella bronchiseptica has been the only pathogen isolated during a course
Galeziok Michal +2 more
doaj +1 more source
Bacillus anthracis edema factor substrate specificity: evidence for new modes of action [PDF]
Since the isolation of Bacillus anthracis exotoxins in the 1960s, the detrimental activity of edema factor (EF) was considered as adenylyl cyclase activity only.
Agrawal +94 more
core +2 more sources
We report a case of spondylodiscitis caused by Bordetella holmesii, an emergent pathogen. This small Gram-negative rod was first known as a cause of invasive infections on asplenic patients. This case describes a spondylodiscitis due to this bacterium in
Safia Nadji +7 more
doaj +1 more source
Antibiotics in acute bronchitis: a meta-analysis. [PDF]
PurposeMost patients with acute bronchitis who seek medical care are treated with antibiotics, although the effectiveness of this intervention is uncertain.
Bent, S +3 more
core +1 more source
Bordetella pertussis, Bordetella bronchiseptica, and Bordetella parapertussis share highly homologous virulence factors and commonly cause respiratory infections in mammals; however, their host specificities and disease severities differ, and the reasons
Aya Fukui-Miyazaki +8 more
doaj +1 more source
Intracranial Infection of Mice with Bordetella pertussis [PDF]
SUMMARY: A bacteriological and histological study was made of the sequence of events in unprotected and protected mice, after intracranial challenge with Bordetella pertussis. No difference in the results was obtained whether mice were injected through the parietal bone or through the foramen magnum.
Berenbaum, M C, Ungar, J, Stevens, W K
openaire +2 more sources
Background Pertussis, a vaccine preventable disease, is still responsible of significant morbidity and mortality around the world, mostly in newborns.
Khalid Katfy +8 more
doaj +1 more source
Type Six Secretion System of Bordetella bronchiseptica and Adaptive Immune Components Limit Intracellular Survival During Infection. [PDF]
The Type Six Secretion System (T6SS) is required for Bordetella bronchiseptica cytotoxicity, cytokine modulation, infection, and persistence. However, one-third of recently sequenced Bordetella bronchiseptica strains of the predominantly human-associated
Liron Bendor +8 more
doaj +1 more source
Validation and implementation of a diagnostic algorithm for DNA Detection of Bordetella pertussis, B. parapertussis, and B-holmesii in a Pediatric Referral Hospital in Barcelona, Spain [PDF]
This study aimed to validate a comprehensive diagnostic protocolbased on real-time PCR for the rapid detection and identification ofBordetella per-tussis,Bordetella parapertussis, andBordetella holmesii, as well as its implementationin the diagnostic ...
Acosta Argueta, Lesly María +5 more
core +2 more sources

