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Tissue Resident Memory Cells: Friend or Foe?
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude +2 more
wiley +1 more source
Molecular Identification of Bacteria by Total Sequence Screening: Determining the Cause of Death in Ancient Human Subjects [PDF]
Research of ancient pathogens in ancient human skeletons has been mainly carried out on the basis of one essential historical or archaeological observation, permitting specific pathogens to be targeted.
Alekseev, Anatoly +34 more
core +1 more source
An increasing number of reports have described the pathogenic nature of several non-classical Bordetella spp. Among them, Bordetella hinzii and Bordetella pseudohinzii have been implicated in a myriad of respiratory-associated infections in humans and ...
Shih Keng Loong +5 more
doaj +1 more source
CLINICAL CASE REPORT: PERTUSSIS INFECTION FOLLOWED BY A PARAPERTUSSIS INFECTION IN THE SAME CHILD
Whooping cough is a vaccine-preventable, acute respiratory disease caused by the gram-negative bacterium Bordetella pertussis. In recent years there has been a worldwide reccurrence of pertussis infection.
Nadia Brankova +4 more
doaj +1 more source
Transient marked reactive lymphocytosis in a puppy suspected to be secondary to recent vaccination
A 3‐month‐old male Bernese Mountain dog was presented with a 10‐day history of vomiting, vocalisation and abdominal discomfort following vaccination. Physical examination revealed subtle peripheral lymphadenopathy. Haematological testing revealed borderline anaemia, thrombocytopenia and moderate lymphocytosis with a high proportion of reactive or ...
J. Ruel +5 more
wiley +1 more source
The intranasal infection of mice with Bordetella pertussis [PDF]
Bordetella pertussis instified by the intranasal route into the lungs of mice multiply without difficulty even from small inocula, although B. pertussis is not a natural pathogen for mice and mouse to mouse infection could not be demonstrated. When the initial dose was large the bacilli multiplied until the number in the lungs reached a critical level ...
J M, DOLBY, D C, THOW, A F, STANDFAST
openaire +2 more sources
Bordetella biofilms: a lifestyle leading to persistent infections [PDF]
Bordetella bronchiseptica and B. pertussis are Gram-negative bacteria that cause respiratory diseases in animals and humans. The current incidence of whooping cough or pertussis caused by B.
Deora, Rajendar +4 more
core +1 more source
BACKGROUND: Bordetella pertussis infections continue to be a major public health challenge in Canada. Polymerase chain reaction (PCR) assays to detect B pertussis are typically based on the multicopy insertion sequence IS481, which offers
Mohammad Rubayet Hasan +4 more
doaj +1 more source
MinJ is a nine‐pass transmembrane protein with a cytoplasmic PDZ domain. The PDZ domain, while required for division, is dispensable for localization, and deletion of the transmembrane segments 6 and 7 results in a hyper‐minicell phenotype. ABSTRACT The Min system disassembles FtsZ‐rings after septation in Bacillus subtilis and is localized to the ...
Kehinde O. Adebiyi +5 more
wiley +1 more source
Opportunistic Pulmonary Bordetella hinzii Infection after Avian Exposure
We report 2 cases of pulmonary Bordetella hinzii infection in immunodeficient patients. One of these rare cases demonstrated the potential transmission of the bacteria from an avian reservoir through occupational exposure and its persistence in humans ...
Aude Fabre +11 more
doaj +1 more source

