Results 51 to 60 of about 3,278,826 (260)

Aerosol infection of mice with Bordetella pertussis [PDF]

Infection and Immunity, 1980
Aerosol inhalation of Bordetella pertussis Tohama phase I resulted in a reproducible and uniform infection of mice (strain DDY or ICR). Mice in groups of 10 exposed for 30 min to aerosols generated from bacterial suspensions of 10(9) and 10(10) organisms per ml resulted in mean bacterial counts of 2.3 (+/- 0.3) X 10(4) and 1.0 (+/- 0.3) X 10(5) colony ...
Y, Sato, K, Izumiya, H, Sato, J L, Cowell, C R, Manclark   +4 more
openaire   +2 more sources

Cytotoxicity of the effector protein BteA was attenuated in Bordetella pertussis by insertion of an alanine residue

bioRxiv, 2020
Bordetella bronchiseptica and Bordetella pertussis are closely related respiratory pathogens that evolved from a common bacterial ancestor. While B. bronchiseptica has an environmental reservoir and mostly establishes chronic infections in a broad range ...
Jan Bayram, Ivana Malcova, Larisa Sinkovec, J. Holubová, Gaia Streparola, David Jurnečka, J. Kučera, R. Sedláček, P. Šebo, Jana Kamanová   +9 more
semanticscholar   +1 more source

Swedish Infants Developed Pertussis at a Younger Age if Their Mother Was the Possible Source of Infection in 2009–2015

Acta Paediatrica, EarlyView.
ABSTRACT Aim The aim of this study was to investigate the possible source of laboratory‐confirmed pertussis in infants under 6 months of age. Methods This nationwide prospective study was based on laboratory‐confirmed cases reported in the enhanced pertussis surveillance in Sweden from 2009 to 2015. The parents or carers of 345 infants were interviewed
Bernice Aronsson, Lennart Nilsson, Jann Storsaeter, Henrik Källberg, Emma Appelqvist   +4 more
wiley   +1 more source

Bordetella pseudohinzii targets cilia and impairs tracheal cilia-driven transport in naturally acquired infection in mice

Scientific Reports, 2018
Several species of the Gram-negative genus Bordetella are the cause of respiratory infections in mammals and birds, including whooping cough (pertussis) in humans.
Alexander Perniss, Nadine Schmidt, Corinne Gurtner, Kristina Dietert, Oliver Schwengers, Markus Weigel, Julia Hempe, Christa Ewers, Uwe Pfeil, Ulrich Gärtner, Achim D. Gruber, Torsten Hain, Wolfgang Kummer   +12 more
doaj   +1 more source

Severe problem of macrolides resistance to common pathogens in China

Frontiers in Cellular and Infection Microbiology, 2023
With the widespread use of macrolide antibiotics in China, common pathogens causing children’s infections, such as Streptococcus pneumoniae, Streptococcus (including Group A streptococcus, Group B streptococcus), Staphylococcus aureus, Bordetella ...
Jialin Li, Jialin Li, Lesen Liu, Hua Zhang, Hua Zhang, Jing Guo, Jing Guo, Xiaoling Wei, Xiaoling Wei, Min Xue, Min Xue, Xiang Ma, Xiang Ma   +12 more
doaj   +1 more source

Immunization with whole cell but not acellular pertussis vaccines primes CD4 TRM cells that sustain protective immunity against nasal colonization with Bordetella pertussis

Emerging Microbes and Infections, 2019
Protective immunity wanes rapidly after immunization of children with acellular pertussis (aP) vaccines and these vaccines do not prevent nasal colonization or transmission of Bordetella pertussis in baboons. In this study, we examined the role of tissue-
Mieszko M. Wilk, Lisa Borkner, Alicja Misiak, Lucy M. Curham, Aideen C. Allen, K. Mills   +5 more
semanticscholar   +1 more source

Bordetella bronchiseptica promotes adherence, colonization, and cytotoxicity of Streptococcus suis in a porcine precision-cut lung slice model

Virulence, 2020
Bordetella (B.) bronchiseptica and Streptococcus (S.) suis are major pathogens in pigs, which are frequently isolated from co-infections in the respiratory tract and contribute to the porcine respiratory disease complex (PRDC). Despite the high impact of
Désirée Vötsch, Maren Willenborg, W. Baumgärtner, M. Rohde, P. Valentin-Weigand   +4 more
semanticscholar   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source

Opportunistic Pulmonary Bordetella hinzii Infection after Avian Exposure

Emerging Infectious Diseases, 2015
We report 2 cases of pulmonary Bordetella hinzii infection in immunodeficient patients. One of these rare cases demonstrated the potential transmission of the bacteria from an avian reservoir through occupational exposure and its persistence in humans ...
Aude Fabre, Clarisse Dupin, François Bénézit, Julien Goret, Caroline Piau, Stéphane Jouneau, Sophie Guillot, Francis Mégraud, Samer Kayal, Benoit Desrues, Alain Le Coustumier, Nicole Guiso   +11 more
doaj   +1 more source

DIAGNOSIS OF INFECTION WITH BORDETELLA PERTUSSIS [PDF]

Pediatric Research, 1987
In the past, three methods have been used to provide laboratory confirmation of the clinical diagnosis of infection with B.pertussis (Bp): culture, direct fluorescein-labelled antibody-stained smear (FA) and serology. Each, however, is frought with problems, including requirement for fresh, selective medium, slow growth of Bp organisms, interobserver ...
Erik L Hewlett, Kenneth Bromberg, Mary C Gray, David R Harcus, Martha A McLafferty   +4 more
openaire   +1 more source