Results 91 to 100 of about 94,944 (270)

Pertussis with severe pulmonary hypertension in a newborn with good outcome - case report Infecção por Bordetella pertussis com hipertensão pulmonar grave num recém -nascido com boa evolução clínica - Caso clínico

open access: yesRevista Portuguesa de Pneumologia, 2008
In spite of the availability and widespread use of vaccines, pertussis is far from controlled. Newborns and infants too young to be fully vaccinated, born from mothers with low antibody titers to Bordetella pertussis, are highly susceptible to infection ...
Sérgia Soares   +6 more
doaj  

Understanding the Mechanism of Translocation of Adenylate Cyclase Toxin across Biological Membranes [PDF]

open access: yes, 2017
Adenylate cyclase toxin (ACT) is one of the principal virulence factors secreted by the whooping cough causative bacterium Bordetella pertussis, and it has a critical role in colonization of the respiratory tract and establishment of the disease.
Belloso Uribe, Kepa   +4 more
core   +2 more sources

Neopterin as a Tool for Primate Ecoimmunology: Current Knowledge, Practical Application, and New Directions From Captivity to the Wild

open access: yesAmerican Journal of Primatology, Volume 87, Issue 10, October 2025.
Neopterin is a sensitive and specific biomarker of intracellular pathogen infection and chronic inflammation, and affected by environmental, life‐history, and sex‐contextual factors. This review offers best‐practice guidelines and practical advice on sample collection, storage, and analysis in primates when used for ecoimmunological conservation and ...
Verena Behringer, Caroline Deimel
wiley   +1 more source

Pertussis em Portugal – A importância de uma nova estratégia vacinal

open access: yesRevista Portuguesa de Pneumologia, 2010
Resumo: A introdução da vacina antipertussis nos programas de vacinação originou uma diminuição drástica da incidência de tosse convulsa no mundo.
Susana Gama de Sousa, Henrique Barros
doaj   +1 more source

Yin and yang of interleukin-17 in host immunity to infection [version 1; referees: 2 approved] [PDF]

open access: yes, 2017
The interleukin-17 (IL-17) family cytokines, such as IL-17A and IL-17F, play important protective roles in host immune response to a variety of infections such as bacterial, fungal, parasitic, and viral.
Das, Shibali, Khader, Shabaana
core   +3 more sources

Evaluation of Adenylate Cyclase Toxoid Antigen in Acellular Pertussis Vaccines by Using a Bordetella pertussis Challenge Model in Mice

open access: yesInfection and Immunity, 2018
Bordetella pertussis is the primary causative agent of pertussis (whooping cough), which is a respiratory infection that leads to a violent cough and can be fatal in infants. There is a need to develop more effective vaccines because of the resurgence of
Dylan T. Boehm   +16 more
semanticscholar   +1 more source

Bordetella pertussis

open access: yesPractical Clinical Microbiology and Infectious Diseases, 2020
A species of bacteria within the phylum Proteobacteria consisting of gram-negative aerobic coccobacillus that are the causative agent of pertussis.
Firza Alexander Gronthoud
semanticscholar   +1 more source

Amiodarone‐Induced Pulmonary Toxicity in an Elderly Patient: A Case Report

open access: yesClinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Amiodarone, a widely utilized and effective class III antiarrhythmic agent, carries a significant risk of severe organ toxicities, notably including the pulmonary system. This report details a case of an 82‐year‐old female who developed amiodarone‐induced pulmonary toxicity (APT) following 2 years of standard 200 mg daily maintenance therapy ...
Bal Krishna Subedi   +4 more
wiley   +1 more source

Recent advances and challenges in antigen engineering & vaccine development [PDF]

open access: yes, 2014
textVaccines play a vital role in public health by preventing infectious disease across the globe. Vaccine formulations represent a weakened form of a microbe or toxin that is injected into the human body to elicit an immune response, generating ...
Kornahrens, William Joseph
core  

Genomic Survey of Bordetella pertussis Diversity, United States, 2000–2013

open access: yesEmerging Infectious Diseases, 2018
We characterized 170 complete genome assemblies from clinical Bordetella pertussis isolates representing geographic and temporal diversity in the United States. These data capture genotypic shifts, including increased pertactin deficiency, occurring amid
M. R. Weigand   +5 more
semanticscholar   +1 more source

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