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Virulence Factors of Bordetella pertussis.
百日咳はワクチン接種の普及により日本では過去の病気となりつつあるが, 予防接種の行き渡らない国々では今なお猛威を奮っている小児の呼吸器伝染病で, 病因的にはジフテリアと同様, 毒素性疾患として理解し得る。最近では伝染源としての成人感染者が問題視され始めたが, 呼吸器感染症の常として根絶は殆ど不可能であり, 感染の予防, 治療に関する研究成果のみが百日咳の制圧を可能にする途である。本小文では, 百日咳菌の産生する病原因子のうち, 感染の第一段階である宿主細胞への菌の吸着に関与する接着因子 (繊維状赤血球凝集素, 線毛, パータクチン) および百日咳症の発現に関与する毒素類 (百日咳毒素, アデニレートシクラーゼ毒素, 気管上皮細胞毒素, 皮膚壊死毒素, 内毒素) の産生, 性状 ...
openaire +3 more sources
We evaluated the diagnostic performance of a genomic DNA amplification method for Bordetella pertussis and Bordetella parapertussis compared with culture isolation. Aliquots from B. pertussis and B.
GABUTTI, Giovanni +5 more
core +1 more source
Pertussis in young infants: a severe vaccine-preventable disease
Pertussis (also known as whooping cough) is a highly contagious disease mainly caused by the bacterium Bordetella pertussis. It is a strictly human disease and affects all ages.
Marco Aurélio Palazzi Sáfadi
doaj
Virulence factors of Bordetella pertussis [PDF]
Bordetella pertusis is a Gram-negative, aerobic, non-spore-forming coccobacillus. Although it's strictly human pathogen, it's possible to infect other mammals at laboratory conditions.
Držmíšek, Jakub
core
Best practices for health care professionals on the use of polymerase chain reaction (PCR) for diagnosing pertussis [PDF]
Wednesday, February 16, 2011,11:45 ET (1145 PM ET)CDCHAN-00319-2011 -02- 16-ADV-NWith the continuing resurgence of pertussis, health care professionals will likely see more patients with suspected pertussis.
core
reservedIntroduzione: Bordetella pertussis è l’agente eziologico della pertosse, infezione batterica altamente contagiosa. Nel 2024 si è assistito ad un notevole aumento dell’incidenza di pertosse nei paesi dell’Unione Europea, in particolare nei ...
ZANELLA, ANTONIO
core
Molecular aspects of Bordetella pertussis pathogenesis
The molecular mechanisms of Bordetella virulence are now well understood, and many virulence factors have been identified and characterized at the molecular level.
Locht, Camille
core
Ryoichi, Saito, Kazunari, Kamachi
+5 more sources
The Immunology of Bordetella pertussis Infection [PDF]
Mills, Kingston H.G. +5 more
openaire +3 more sources
Evaluation of Specificity of BP3385 for Bordetella pertussis Detection
BP3385 has been proposed as a diagnostic PCR target for discriminating between Bordetella pertussis and other Bordetella species that also infect humans.
Karen B. Register +2 more
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