Results 1 to 10 of about 7,870 (170)

Interplay of virulence factors and signaling molecules: albumin and calcium-mediated biofilm regulation in Bordetella bronchiseptica [PDF]

Journal of Bacteriology
Bordetella bronchiseptica, a respiratory pathogen capable of infecting various mammals, including humans, is associated with chronic infections. B.
Sabrina Laura Mugni, Nicolás Ambrosis, George A. O´Toole, Federico Sisti, Julieta Fernández   +4 more
doaj   +4 more sources

Pathogenicity and virulence of Bordetella pertussis and its adaptation to its strictly human host

Virulence, 2021
The highly contagious whooping cough agent Bordetella pertussis has evolved as a human-restricted pathogen from a progenitor which also gave rise to Bordetella parapertussis and Bordetella bronchiseptica.
Camille Locht, Alex Rivera-Millot, Violaine Dubois   +2 more
exaly   +2 more sources

The Type III Secreted Protein BspR Regulates the Virulence Genes in Bordetella bronchiseptica [PDF]

PLoS ONE, 2012
Bordetella bronchiseptica is closely related with B. pertussis and B. parapertussis, the causative agents of whooping cough. These pathogenic species share a number of virulence genes, including the gene locus for the type III secretion system (T3SS ...
Asaomi Kuwae, Akio Abe, Jun Kurushima
exaly   +2 more sources

Isolation, Antimicrobial Resistance Phenotypes, and Virulence Genes of Bordetella bronchiseptica From Pigs in China, 2018–2020

Frontiers in Veterinary Science, 2021
Bordetella bronchiseptica is a leading cause of respiratory diseases in pigs. However, epidemiological data of B. bronchiseptica in pigs particularly in China, the largest pig rearing country in the world is still limited.
Zhong Peng, Yue Zhang, Bin Wu
exaly   +3 more sources

Bordetella BcrH1 and BcrH2 Are Specific Chaperones for the Pore-Forming Complex. [PDF]

Microbiol Immunol
ABSTRACT Bordetella has a type III secretion system that secretes virulence proteins crucial to the establishment of infection. The genes encoding components of the Bordetella type III secretion system are located in the bsc region on the chromosome. This region includes the bcrH1 and bcrH2 genes, which respectively encode the proteins BcrH1 and BcrH2.
Kishino Y, Ogawa T, Sato H, Abe A, Kuwae A.   +4 more
europepmc   +2 more sources

A Case of Sepsis Caused by ST80 Multidrug-Resistant Enterococcus faecium With Concurrent Klebsiella pneumoniae Infection in a Dog. [PDF]

Vet Med Sci
An 8‐year‐old dog developed acute respiratory distress that progressed to sepsis and death. Multidrug‐resistant Enterococcus faecium ST80 was isolated from the liver and kidney, while Klebsiella pneumoniae was detected in the lung by PCR. Whole‐genome sequencing showed that the ST80 isolates were genetically identical, suggesting hematogenous spread ...
Seo HM, La TM, Seo YR, Lee DY, Han HJ, Hyeon JY.   +5 more
europepmc   +2 more sources

Released palmitic acid–mediated TLR4/NF-κB activation enhances the virulence of Bordetella pertussis MT28 lineage [PDF]

Nature Communications
Whooping cough has resurged globally despite high vaccination coverage. In China, a macrolide-resistant (MR) Bordetella pertussis lineage carrying the high-virulence ptxP3 allele, termed ptxP3 MR-MT28 (MT28), has been increasingly reported as a ...
Shuangshuang Li, Mingliang Chen, Xudong Feng, Yuquan Gao, Xuan Hong, Nadira Nurxat, Tianchi Chen, Guoxiu Xiang, Ziyu Yang, Ying Jian, Qing Wei, Bisheng Shi, Xiaowei Ma, Yanming Lu, Zhen Shen, Muyun Wei, Lei He, Min Li   +17 more
doaj   +2 more sources

From Lake Victoria to the Tap: Antibiotic Resistance and Pathogenic Contamination of Kisumu City Water Supply and Wastewater Network. [PDF]

Trop Med Int Health
ABSTRACT Waterborne diseases and antimicrobial resistance (AMR) pose mounting public health threats across sub‐Saharan Africa, particularly in rapidly urbanising regions dependent on untreated or poorly treated surface waters. This study applied shotgun metagenomic sequencing to characterise microbial communities, virulence factors and antibiotic ...
Reva ON, Sifuna A, Orata F, Omolo C, Iramiot JS, Enright MC, Mutshembele A, Zhou J, Shivoga WA.   +8 more
europepmc   +2 more sources

Nuanced differences in adenylate cyclase toxin production, acylation, and secretion may contribute to the evolution of virulence in Bordetella species [PDF]

mBio
Bordetella pertussis, which causes the acute human disease whooping cough, evolved from Bordetella bronchiseptica, which causes long-term, chronic infections in a broad range of mammals. Both B. pertussis and B.
Alexa R. Wolber, Liliana S. McKay, Katlyn B. Mote, Richard M. Johnson, Carol S. Inatsuka, Peggy A. Cotter   +5 more
doaj   +2 more sources

Structural and functional specialization of Bordetella pertussis DsbA for pertussis toxin folding. [PDF]

Protein Sci
Abstract Disulphide bonds (Dsbs) are essential for the folding, stability, and function of many secreted and membrane‐associated proteins in bacteria. In Gram‐negative species, these bonds are introduced by the Dsb enzyme family, with DsbA acting as the primary thiol oxidase.
Penning S, Mitchell L, Hong Y, Cunliffe T, Subedi P, Wang G, Hor L, Totsika M, Paxman JJ, Heras B.   +9 more
europepmc   +2 more sources