Results 21 to 30 of about 7,870 (170)
Tn5-induced mutations affecting virulence factors of Bordetella pertussis [PDF]
Infection and Immunity, 1983 Transposon Tn5 was used to isolate mutants of Bordetella pertussis. Strains with Tn5 insertions were screened for loss of virulence-associated factors, including filamentous hemagglutinin, hemolysin, and pertussis toxin. Several mutants deficient for hemolysin production were obtained.
A A, Weiss +3 more
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BipA Is Associated with Preventing Autoagglutination and Promoting Biofilm Formation in Bordetella holmesii. [PDF]
PLoS ONE, 2016 Bordetella holmesii causes both invasive and respiratory diseases in humans. Although the number of cases of pertussis-like respiratory illnesses due to B. holmesii infection has increased in the last decade worldwide, little is known about the virulence
Yukihiro Hiramatsu +6 more
doaj +1 more source
mBio, 2018 Bordetella pertussis, Bordetella bronchiseptica, and Bordetella parapertussis share highly homologous virulence factors and commonly cause respiratory infections in mammals; however, their host specificities and disease severities differ, and the reasons
Aya Fukui-Miyazaki +8 more
doaj +1 more source
Bordetella pertussisVirulence Factors Affect Phagocytosis by Human Neutrophils [PDF]
Infection and Immunity, 2000 ABSTRACTThe interaction between human neutrophils and wild-typeBordetella pertussisor mutants expressing altered lipopolysaccharide or lacking virulence factors—pertussis toxin, adenylate cyclase toxin, dermonecrotic toxin, filamentous hemagglutinin (FHA), pertactin, or BrkA—was examined.
C L, Weingart, A A, Weiss
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Dermonecrotic toxin and tracheal cytotoxin, putative virulence factors of Bordetella avium [PDF]
Infection and Immunity, 1988 We examined Bordetella avium for virulence factors common to Bordetella pertussis, including pertussis toxin, filamentous hemagglutinin, adenylate cyclase, dermonecrotic toxin, and tracheal cytotoxin. B. avium produced a dermonecrotic toxin and a tracheal cytotoxin. The dermonecrotic toxin of B.
C R, Gentry-Weeks +5 more
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BMC Genomics, 2012 Background The classical Bordetella subspecies are phylogenetically closely related, yet differ in some of the most interesting and important characteristics of pathogens, such as host range, virulence and persistence.
Park Jihye +11 more
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Emerging Microbes and Infections, 2023 Bordetella pertussis is a Gram-negative, strictly human re-emerging respiratory pathogen and the causative agent of whooping cough. Similar to other Gram-negative pathogens, B.
Jakub Držmíšek +4 more
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Molecular evolution of the two-component system BvgAS involved in virulence regulation in Bordetella. [PDF]
PLoS ONE, 2009 The whooping cough agent Bordetella pertussis is closely related to Bordetella bronchiseptica, which is responsible for chronic respiratory infections in various mammals and is occasionally found in humans, and to Bordetella parapertussis, one lineage of
Julien Herrou +7 more
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Virulence Factors of Bordetella pertussis.
Nippon Saikingaku Zasshi, 1996 百日咳はワクチン接種の普及により日本では過去の病気となりつつあるが, 予防接種の行き渡らない国々では今なお猛威を奮っている小児の呼吸器伝染病で, 病因的にはジフテリアと同様, 毒素性疾患として理解し得る。最近では伝染源としての成人感染者が問題視され始めたが, 呼吸器感染症の常として根絶は殆ど不可能であり, 感染の予防, 治療に関する研究成果のみが百日咳の制圧を可能にする途である。本小文では, 百日咳菌の産生する病原因子のうち, 感染の第一段階である宿主細胞への菌の吸着に関与する接着因子 (繊維状赤血球凝集素, 線毛, パータクチン) および百日咳症の発現に関与する毒素類 (百日咳毒素, アデニレートシクラーゼ毒素, 気管上皮細胞毒素, 皮膚壊死毒素, 内毒素) の産生, 性状 ...
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mSphere, 2019 Bordetella pertussis, B. parapertussis, and B. bronchiseptica cause respiratory infections, many of which are characterized by coughing of the infected hosts.
Keiji Nakamura +7 more
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