Results 11 to 20 of about 7,528,433 (208)

The virulence factors ofBordetella pertussis: a matter of control [PDF]

FEMS Microbiology Reviews, 2001
Bordetella pertussis is the causative agent of whooping cough, a contagious childhood respiratory disease. Increasing public concern over the safety of whole-cell vaccines led to decreased immunisation rates and a subsequent increase in the incidence of the disease.
Smith, AM, Guzman, CA, Walker, MJ
openaire   +6 more sources

The missing link: Bordetella petrii is endowed with both the metabolic versatility of environmental bacteria and virulence traits of pathogenic Bordetellae [PDF]

BMC Genomics, 2008
Background Bordetella petrii is the only environmental species hitherto found among the otherwise host-restricted and pathogenic members of the genus Bordetella.
Schneiker-Bekel Susanne, Rückert Christian, Nakunst Diana, Mormann Sascha, Meyer Folker, Linke Burkhard, Link Stefanie, Larisch Christof, Khachane Amit N, Herrmann Stefanie, Gaigalat Lars, Ebensen Thomas, Choudhuri Jomuna V, Buhrmester Jens, Bartels Daniela, Lechner Melanie, Koebnik Ralf, Pieper Dietmar H, Martins dos Santos Vítor AP, Sebaihia Mohammed, Guzman Carlos A, Gross Roy, Schulze Kai, Vorhölter Frank-Jörg, Yevsa Tetyana, Engle Jacquelyn T, Goldman William E, Pühler Alfred, Göbel Ulf B, Goesmann Alexander, Blöcker Helmut, Kaiser Olaf, Martinez-Arias Rosa   +32 more
doaj   +2 more sources

Comparative genomics of the classical Bordetella subspecies: the evolution and exchange of virulence-associated diversity amongst closely related pathogens [PDF]

BMC Genomics, 2012
Background The classical Bordetella subspecies are phylogenetically closely related, yet differ in some of the most interesting and important characteristics of pathogens, such as host range, virulence and persistence.
Park Jihye, Zhang Ying, Buboltz Anne M, Zhang Xuqing, Schuster Stephan C, Ahuja Umesh, Liu Minghsun, Miller Jeff F, Sebaihia Mohammed, Bentley Stephen D, Parkhill Julian, Harvill Eric T   +11 more
doaj   +2 more sources

Positive transcriptional feedback at the bvg locus controls expression of virulence factors in Bordetella pertussis.

Proceedings of the National Academy of Sciences, 1990
Regulation of the genes coding for virulence factors in Bordetella pertussis is controlled by the bvg locus, which encodes one putative sensory protein (BvgS) and one positive regulator of transcription (BvgA). We have studied the transcription of the bvg locus and found that this is controlled by a 350-base-pair DNA fragment, which contains five ...
Scarlato V., Prugnola A., Arico B., Rappuoli R.   +3 more
openaire   +5 more sources

Interplay of virulence factors and signaling molecules: albumin and calcium-mediated biofilm regulation in Bordetella bronchiseptica

Journal of Bacteriology
Bordetella bronchiseptica, a respiratory pathogen capable of infecting various mammals, including humans, is associated with chronic infections. B.
Sabrina Laura Mugni, Nicolás Ambrosis, George A. O´Toole, Federico Sisti, Julieta Fernández   +4 more
doaj   +3 more sources

Microbiological, Molecular Diagnosis and Antimicrobial Resistance of Bordetella bronchiseptica in the Equine Reproductive Tract in Brazil. [PDF]

Vet Med Sci
First report of Bordetella bronchiseptica in the reproductive tract of Brazilian mares. Uterine lavage samples from mares with endometritis and infertility were positive by culture, PCR (237 bp flaA), sequencing and phylogenetic analysis. Isolates showed multidrug resistance, emphasizing the relevance of this pathogen in equine reproductive disorders ...
Gallo SSM, Bernardino MLA, Júnior LASDM, Oliveira FCR, Barreto MAP, Folly MM.   +5 more
europepmc   +2 more sources

Bordetella BcrH1 and BcrH2 Are Specific Chaperones for the Pore-Forming Complex. [PDF]

Microbiol Immunol
ABSTRACT Bordetella has a type III secretion system that secretes virulence proteins crucial to the establishment of infection. The genes encoding components of the Bordetella type III secretion system are located in the bsc region on the chromosome. This region includes the bcrH1 and bcrH2 genes, which respectively encode the proteins BcrH1 and BcrH2.
Kishino Y, Ogawa T, Sato H, Abe A, Kuwae A.   +4 more
europepmc   +2 more sources

Virulence factor secretion and translocation by Bordetella species [PDF]

Current Opinion in Microbiology, 2009
Here we review the Bordetella virulence secretome with an emphasis on factors that translocate into target cells. Recent advances in understanding the functions of adenylate cyclase toxin, a type 1 secretion system (T1SS) substrate, and pertussis toxin, a type IV secretion system (T4SS) substrate, are briefly described and a compilation of additional ...
Ruchi, Shrivastava, Jeff F, Miller
openaire   +2 more sources

A Case of Sepsis Caused by ST80 Multidrug-Resistant Enterococcus faecium With Concurrent Klebsiella pneumoniae Infection in a Dog. [PDF]

Vet Med Sci
An 8‐year‐old dog developed acute respiratory distress that progressed to sepsis and death. Multidrug‐resistant Enterococcus faecium ST80 was isolated from the liver and kidney, while Klebsiella pneumoniae was detected in the lung by PCR. Whole‐genome sequencing showed that the ST80 isolates were genetically identical, suggesting hematogenous spread ...
Seo HM, La TM, Seo YR, Lee DY, Han HJ, Hyeon JY.   +5 more
europepmc   +2 more sources

Combined RNAseq and ChIPseq Analyses of the BvgA Virulence Regulator of Bordetella pertussis

mSystems, 2020
Bordetella pertussis regulates the production of its virulence factors by the two-component system BvgAS. In the virulence phase, BvgS phosphorylates BvgA, which then activates the transcription of virulence-activated genes (vags).
Loïc Coutte, Rudy Antoine, Stephanie Slupek, Luis Solans, Julien Derop, Amelie Bonnefond, David Hot, Camille Locht   +7 more
doaj   +3 more sources