Results 41 to 50 of about 7,528,433 (208)

Genomic evidence for the evolution of Streptococcus equi : host restriction, increased virulence, and genetic exchange with human pathogens [PDF]

, 2009
The continued evolution of bacterial pathogens has major implications for both human and animal disease, but the exchange of genetic material between host-restricted pathogens is rarely considered. Streptococcus equi subspecies equi (S.
Parkhill Julian, Maskell, Duncan, Kehoe Michael, Robinson, Carl, Maiden, MC, Spratt, BG, Bason, Nathalie C., Aanensen, David M., Simmonds, M, Aanensen David M., Romain Paillot, Jourdan Thibaud, Willey, David, Maskell Duncan J., Aanensen, David, Katy Webb, Nathalie C Bason, Nancy E Holroyd, Ainslie, F, Maskell, DJ, Robinson Carl, Holden, Matthew, Simmonds Mark, Paillot Romain, Steward, KF, Jourdan, Thibaud, David M Aanensen, Bentley Stephen D., Jolley Keith A., Neil Chanter, Quail, Michael A., Stephen D Bentley, Webb, Katy, Holden, MT, Maiden Martin C. J., Julian Parkhill, Brooks Karen, Spratt Brian G., Maiden, MCJ, Fern Ainslie, Mark Simmonds, Keith A Jolley, Spratt, Brian, Holroyd, NE, Parkhill, Julian, Heather Zoe, Chanter, N, Michael Kehoe, Jolley, KA, David Willey, Bentley, Stephen, Ainslie, Fern, Quail, MA, Waller, Andrew S., Sanders Mandy, Waller, AS, Heather, Zoe, Waller, Andrew, Parkhill, J, Bason, NC, Sanders, M, Carl Robinson, Bason Nathalie C., Steward, Karen, Brooks, Karen, Bentley, Stephen D., Paillot, R, Wessels, Michael, Maiden, Martin, Holden, Matthew T. G., Zoe Heather, Robinson, C, Mungall Karen, Steward, Karen F., Quail Michael A., Paillot, Romain, Sanders, Mandy, Quail, Michael, Bason, Nathalie, Holroyd, Nancy, Maiden, Martin C. J., Andrew S Waller, Jolley, Keith A., Willey, D, Brian G Spratt, Chanter Neil, Mungall, K, Webb, K, Holden, MTG, Matthew T G Holden, Holroyd Nancy E., Kehoe, M, Karen F Steward, Maskell, Duncan J., Heather, Z, Holden Matthew T. G., Bentley, SD, Duncan J Maskell, Chanter, Neil, Aanensen, DM, Karen Brooks, Thibaud Jourdan, Brooks, K, Ainslie Fern, Steward Karen F., Holroyd, Nancy E., Mandy Sanders, Michael A Quail, Spratt, Brian G., Willey David, Simmonds, Mark, Waller Andrew S., Mungall, Karen, Webb Katy, Karen Mungall, Jourdan, T, Kehoe, Michael, Martin C J Maiden, Jolley, Keith   +118 more
core   +1 more source

Comparative Phosphoproteomics of Classical Bordetellae Elucidates the Potential Role of Serine, Threonine and Tyrosine Phosphorylation in Bordetella Biology and Virulence. [PDF]

, 2022
The Bordetella genus is divided into two groups: classical and non-classical. Bordetella pertussis, Bordetella bronchiseptica and Bordetella parapertussis are known as classical bordetellae, a group of important human pathogens causing whooping cough or ...
Kaur, S, Zhong, L, Luu, LDW, Lan, R, Raftery, MJ   +4 more
core   +1 more source

Balance between Coiled-Coil Stability and Dynamics Regulates Activity of BvgS Sensor Kinase in Bordetella

mBio, 2016
The two-component system BvgAS controls the expression of the virulence regulon of Bordetella pertussis. BvgS is a prototype of bacterial sensor kinases with extracytoplasmic Venus flytrap perception domains.
E. Lesne, E.-M. Krammer, E. Dupre, C. Locht, M. F. Lensink, R. Antoine, F. Jacob-Dubuisson   +6 more
doaj   +1 more source

Molecular Identification of Bacteria by Total Sequence Screening: Determining the Cause of Death in Ancient Human Subjects [PDF]

, 2011
Research of ancient pathogens in ancient human skeletons has been mainly carried out on the basis of one essential historical or archaeological observation, permitting specific pathogens to be targeted.
Alekseev, Anatoly, Alekseev, Anatoly N., Thèves, Catherine, Dabernat, Henri, François Xavier Ricaut, Fabre Richard, Alekseev, Anatoly N, Crubézy, Eric, Anatoly N Alekseev, Eric Crubézy, Alice Senescau, Vanin Stefano, Dabernat Henri, Crubézy Eric, Keyser, Christine, Fabre, Richard, Bertrand Ludes, Senescau Alice, Ludes Bertrand, Senescau, Alice, Ricaut François Xavier, Vanin, Stefano, Richard Fabre, Ludes, Bertrand, Catherine Thèves, Christine Keyser, Stefano Vanin, Adler, Ben, Ricaut, François-Xavier, Alekseev Anatoly N., Anatoly N. Alekseev, Ricaut, François Xavier, Keyser Christine, Henri Dabernat, Thèves Catherine   +34 more
core   +1 more source

sigE facilitates the adaptation of Bordetella bronchiseptica to stress conditions and lethal infection in immunocompromised mice

BMC Microbiology, 2012
Background The cell envelope of a bacterial pathogen can be damaged by harsh conditions in the environment outside a host and by immune factors during infection.
Barchinger Sarah E, Zhang Xuqing, Hester Sara E, Rodriguez Maria E, Harvill Eric T, Ades Sarah E   +5 more
doaj   +1 more source

RETRACTED: Melanin Produced by Bordetella parapertussis Confers a Survival Advantage to the Bacterium during Host Infection

mSphere, 2021
Bordetella parapertussis causes respiratory infection in humans, with a mild pertussis (whooping cough)-like disease. The organism produces a brown pigment, the nature and biological significance of which have not been elucidated.
Yukihiro Hiramatsu, Takashi Nishida, Dendi Krisna Nugraha, Fuminori Sugihara, Yasuhiko Horiguchi   +4 more
doaj   +1 more source

Differential regulation of type III secretion and virulence genes in Bordetella pertussis and Bordetella bronchiseptica by a secreted anti-σ factor [PDF]

Proceedings of the National Academy of Sciences, 2016
Significance Bordetella bronchiseptica isolates from diverse hosts, including humans, display potent cytotoxicity against a broad range of mammalian cells, which is dependent on type III secretion system (T3SS) effector BteA. In contrast, neither laboratory nor clinical isolates of
Ahuja, Umesh, Shokeen, Bhumika, Cheng, Ning, Cho, Yeonjoo, Blum, Charles, Coppola, Giovanni, Miller, Jeff F   +6 more
openaire   +4 more sources

Pertactin-Deficient Bordetella pertussis with Unusual Mechanism of Pertactin Disruption, Spain, 1986–2018

Emerging Infectious Diseases, 2022
Bordetella pertussis not expressing pertactin has increased in countries using acellular pertussis vaccines (ACV). The deficiency is mostly caused by pertactin gene disruption by IS481.
Alba Mir-Cros, Albert Moreno-Mingorance, M. Teresa Martín-Gómez, Raquel Abad, Iván Bloise, Magda Campins, Alejandro González-Praetorius, M. Nieves Gutiérrez, Héctor Martín-González, Carmen Muñoz-Almagro, M. Ángeles Orellana, Manuela de Pablos, Josep Roca-Grande, Carlos Rodrigo, M. Elena Rodríguez, Sonia Uriona, M. José Vidal, Tomàs Pumarola, M. Nieves Larrosa, Juan José González-López   +19 more
doaj   +1 more source

Virulence Associated Gene 8 of Bordetella pertussis Enhances Contact System Activity by Inhibiting the Regulatory Function of Complement Regulator C1 Inhibitor

Frontiers in Immunology, 2018
Bordetella pertussis is a Gram-negative bacterium and the causative agent of whooping cough. Whooping cough is currently re-emerging worldwide and, therefore, still poses a continuous global health threat. B. pertussis expresses several virulence factors
Elise S. Hovingh, Elise S. Hovingh, Steven de Maat, Alexandra P. M. Cloherty, Steven Johnson, Elena Pinelli, Coen Maas, Ilse Jongerius, Ilse Jongerius   +8 more
doaj   +1 more source

Blockade of the Adenylate Cyclase Toxin Synergizes with Opsonizing Antibodies to Protect Mice against Bordetella pertussis

mBio, 2022
Bordetella produces an array of virulence factors, including the adenylate cyclase toxin (ACT), which is essential, immunogenic in humans, and highly conserved.
Andrea M. DiVenere, Dzifa Amengor, Rui P. Silva, Jory A. Goldsmith, Jason S. McLellan, Jennifer A. Maynard   +5 more
doaj   +1 more source