Results 51 to 60 of about 13,827 (215)
Analysis of Bordetella pertussis populations in European countries with different vaccination policies. [PDF]
, 2005 Despite the widespread use of pertussis vaccines during the last decades, pertussis has remained an endemic disease with frequent epidemic outbreaks. Currently two types of vaccines are used: whole-cell vaccines (WCVs) and recently developed acellular ...
Amersfoorth, S C M van +14 more
core +1 more source
Virulence Factors of Bordetella pertussis.
Nippon Saikingaku Zasshi, 1996 百日咳はワクチン接種の普及により日本では過去の病気となりつつあるが, 予防接種の行き渡らない国々では今なお猛威を奮っている小児の呼吸器伝染病で, 病因的にはジフテリアと同様, 毒素性疾患として理解し得る。最近では伝染源としての成人感染者が問題視され始めたが, 呼吸器感染症の常として根絶は殆ど不可能であり, 感染の予防, 治療に関する研究成果のみが百日咳の制圧を可能にする途である。本小文では, 百日咳菌の産生する病原因子のうち, 感染の第一段階である宿主細胞への菌の吸着に関与する接着因子 (繊維状赤血球凝集素, 線毛, パータクチン) および百日咳症の発現に関与する毒素類 (百日咳毒素, アデニレートシクラーゼ毒素, 気管上皮細胞毒素, 皮膚壊死毒素, 内毒素) の産生, 性状 ...
openaire +3 more sources
Pathogens and Disease, 2022 ABSTRACT Gram-negative pathogenic bacteria constitutively shed outer membrane vesicles (OMVs) which play a significant role in the host–pathogen interaction, eventually determining the outcome of the infection. We previously found that Bordetella pertussis, the etiological agent of whooping cough, survives the innate interaction with ...
Bruno Blancá +7 more
openaire +3 more sources
Frontiers in Immunology, 2018 Bordetella pertussis is a Gram-negative bacterium and the causative agent of whooping cough. Whooping cough is currently re-emerging worldwide and, therefore, still poses a continuous global health threat. B. pertussis expresses several virulence factors
Elise S. Hovingh +8 more
doaj +1 more source
Virulence factors determine attachment and ingestion of nonopsonized and opsonized Bordetella pertussis by human monocytes [PDF]
Infection and Immunity, 1994 In the present study, the role of virulence factors in and the effect of opsonization on the interactions between Bordetella pertussis and human monocytes were investigated. The methods used facilitated the distinction between attachment and ingestion of bacteria by monocytes. Nonopsonized virulent B. pertussis cells attached to monocytes. Nonopsonized
Hazenbos, WLW +4 more
openaire +3 more sources
Journal of Extracellular Biology, Volume 5, Issue 5, May 2026.ABSTRACT Vibrio cholerae inhabits phosphorus‐poor aquatic environments and host intestine, where it expresses genes regulated by the PhoB/PhoR two‐component system in response to inorganic phosphate (Pi) limitation. Like other Gram‐negative bacteria, V.
Matheus Luchetta da Fonseca +9 more
wiley +1 more source
BopN is a Gatekeeper of the Bordetella Type III Secretion System
Microbiology Spectrum, 2023 The classical Bordetella species infect the respiratory tract of mammals. While B. bronchiseptica causes rather chronic respiratory infections in a variety of mammals, the human-adapted species B. pertussis and B.
Kevin Munoz Navarrete +6 more
doaj +1 more source
Molecular aspects of Bordetella pertussis pathogenesis [PDF]
, 2010 The molecular mechanisms of Bordetella virulence are now well understood, and many virulence factors have been identified and characterized at the molecular level.
Camille Locht
core +2 more sources
Type VI secretion: a beginner's guide [PDF]
, 2008 Type VI secretion is a newly described mechanism for protein transport across the cell envelope of Gram-negative bacteria. Components that have been partially characterised include an IcmF homologue, the ATPase ClpV, a regulatory FHA domain protein and ...
Akeda +47 more
core +1 more source
Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.An 8‐year‐old dog developed acute respiratory distress that progressed to sepsis and death. Multidrug‐resistant Enterococcus faecium ST80 was isolated from the liver and kidney, while Klebsiella pneumoniae was detected in the lung by PCR. Whole‐genome sequencing showed that the ST80 isolates were genetically identical, suggesting hematogenous spread ...
Hyung‐min Seo +5 more
wiley +1 more source