Results 51 to 60 of about 7,870 (170)

Differential Regulation of Bvg-Activated Virulence Factors Plays a Role in Bordetella pertussis Pathogenicity [PDF]

Infection and Immunity, 2001
ABSTRACT Bordetella pertussis , the causative agent of whooping cough, regulates expression of many virulence factors via a two-component signal transduction system encoded by the bvgAS regulatory locus.
S M, Kinnear, R R, Marques, N H, Carbonetti   +2 more
openaire   +2 more sources

The contribution of BvgR, RisA, and RisS to global gene regulation, intracellular cyclic-di-GMP levels, motility, and biofilm formation in Bordetella bronchiseptica

Frontiers in Microbiology
Bordetella bronchiseptica is a highly contagious respiratory bacterial veterinary pathogen. In this study the contribution of the transcriptional regulators BvgR, RisA, RisS, and the phosphorylation of RisA to global gene regulation, intracellular cyclic-
Tracy L. Nicholson, Ursula Waack, Ursula Waack, Damarius S. Fleming, Qing Chen, Laura C. Miller, Tod J. Merkel, Scott Stibitz   +7 more
doaj   +1 more source

Clinical and computed tomography findings of fatal poxviral vasculitis in a domestic shorthair cat

Veterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract This report describes the clinical presentation, haematological abnormalities and imaging findings of systemic poxvirus infection in a cat that resulted in widespread severe dermal oedema and systemic inflammatory response syndrome. The cat lacked cutaneous lesions before the onset of dermal oedema, but developed crusting skin lesions and a ...
Mica Taylor, Harriet R. Hall, Hannah Wong, Lorraine Peschard, Emanuele Ricci, Katie E. McCallum   +5 more
wiley   +1 more source

The missing link: Bordetella petrii is endowed with both the metabolic versatility of environmental bacteria and virulence traits of pathogenic Bordetellae

BMC Genomics, 2008
Background Bordetella petrii is the only environmental species hitherto found among the otherwise host-restricted and pathogenic members of the genus Bordetella.
Schneiker-Bekel Susanne, Rückert Christian, Nakunst Diana, Mormann Sascha, Meyer Folker, Linke Burkhard, Link Stefanie, Larisch Christof, Khachane Amit N, Herrmann Stefanie, Gaigalat Lars, Ebensen Thomas, Choudhuri Jomuna V, Buhrmester Jens, Bartels Daniela, Lechner Melanie, Koebnik Ralf, Pieper Dietmar H, Martins dos Santos Vítor AP, Sebaihia Mohammed, Guzman Carlos A, Gross Roy, Schulze Kai, Vorhölter Frank-Jörg, Yevsa Tetyana, Engle Jacquelyn T, Goldman William E, Pühler Alfred, Göbel Ulf B, Goesmann Alexander, Blöcker Helmut, Kaiser Olaf, Martinez-Arias Rosa   +32 more
doaj   +1 more source

Polymorphism inBordetella pertussisPertactin and Pertussis Toxin Virulence Factors in the United States, 1935–1999 [PDF]

The Journal of Infectious Diseases, 2000
To elucidate the potential role of the etiologic agent in recent increases of pertussis incidence in the United States, we studied the polymorphism in pertactin and pertussis toxin, which are Bordetella pertussis proteins important for pathogenesis and immunity. We sequenced regions of their genes (prn and ptx) in 152 B. pertussis strains isolated from
Cassiday, P, Sanden, G, Heuvelman, Krivm, Mooi, Frivm, Bisgard, KM, Popovic, T   +5 more
openaire   +4 more sources

Orthoquinone, Cyclic, and Acyclic α‐Diketone Natural Products: From Food Applications to Pharmacotherapy

Phytochemicals in Food and Medicine, Volume 1, Issue 1, March 2026.
The orthoquinone metabolites from plants have antimicrobial, antioxidant, antiviral, cytotoxic, and anti‐inflammatory effects. ABSTRACT The structural diversity of natural products is vast and fascinating, and they have been recognized as an enormously diverse source of new lead compounds.
Hidayat Hussain, Daijie Wang, Satyajit D. Sarker, Lutfun Nahar, Nilufar Z. Mamadalieva, Jianbo Xiao   +5 more
wiley   +1 more source

The Fim and FhaB adhesins play a crucial role in nasal cavity infection and Bordetella pertussis transmission in a novel mouse catarrhal infection model.

PLoS Pathogens, 2022
Pulmonary infections caused by Bordetella pertussis used to be the prime cause of infant mortality in the pre-vaccine era and mouse models of pertussis pneumonia served in characterization of B. pertussis virulence mechanisms.
Jana Holubova, Ondrej Stanek, Attila Juhasz, Illiassou Hamidou Soumana, Peter Makovicky, Peter Sebo   +5 more
doaj   +1 more source

Exploring the Potential and Evaluating Hydrocarbon Degradation by Novel Antarctic Dietzia and Pusillimonas Isolates From a Pristine Environment

Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.
The Antarctic Dietzia and Pusillimonas isolates were tested for bioremediation applications. Genomic analyses revealed the potential to degrade complex organic compounds, potential virulence factors and resistance genes. Physiological assays showed a wide range of adaptation to abiotic factors and sensitivity to different groups of antibiotics ...
Tomasz Krucoń, Julia Karbowska, Wiktoria Pietrowicz, Robert Stasiuk, Łukasz Drewniak   +4 more
wiley   +1 more source

Allelic variations between vaccine strains and circulating strains in pxtP of Bordetella pertussis in Iran

Vaccine Research, 2015
Introduction: Despite high level of vaccination against pertussis‚ whooping cough has re-emerged as a health threat, especially in infants. This could be related to expansion of Bordetella pertussis with novel alleles for virulence factors including the ...
F Sadeghpour Heravi, VS Nikbin, F Shahcheraghi   +2 more
doaj  

Characterization of Post-Translational Modifications and Cytotoxic Properties of the Adenylate-Cyclase Hemolysin Produced by Various Bordetella pertussis and Bordetella parapertussis Isolates

Toxins, 2017
Bordetella pertussis and Bordetella parapertussis are the causal agents of whooping cough in humans. They produce diverse virulence factors, including adenylate cyclase-hemolysin (AC-Hly), a secreted toxin of the repeat in toxins (RTX) family with ...
Valérie Bouchez, Thibaut Douché, Mélody Dazas, Sophie Delaplane, Mariette Matondo, Julia Chamot-Rooke, Nicole Guiso   +6 more
doaj   +1 more source