Results 51 to 60 of about 7,528,433 (208)

Novel cyclic di-GMP effectors of the YajQ protein family control bacterial virulence [PDF]

open access: yes, 2014
Bis-(3',5') cyclic di-guanylate (cyclic di-GMP) is a key bacterial second messenger that is implicated in the regulation of many critical processes that include motility, biofilm formation and virulence. Cyclic di-GMP influences diverse functions through
Caly, Delphine L.   +32 more
core   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Virulence factors determine attachment and ingestion of nonopsonized and opsonized Bordetella pertussis by human monocytes [PDF]

open access: yesInfection and Immunity, 1994
In the present study, the role of virulence factors in and the effect of opsonization on the interactions between Bordetella pertussis and human monocytes were investigated. The methods used facilitated the distinction between attachment and ingestion of bacteria by monocytes. Nonopsonized virulent B. pertussis cells attached to monocytes. Nonopsonized
Hazenbos, WLW   +4 more
openaire   +3 more sources

Bordetella pertussis outer membrane vesicles as virulence factor vehicles that influence bacterial interaction with macrophages

open access: yesPathogens and Disease, 2022
ABSTRACT Gram-negative pathogenic bacteria constitutively shed outer membrane vesicles (OMVs) which play a significant role in the host–pathogen interaction, eventually determining the outcome of the infection. We previously found that Bordetella pertussis, the etiological agent of whooping cough, survives the innate interaction with ...
Bruno Blancá   +7 more
openaire   +3 more sources

Enhancing the Secretion Systems: Genetic Engineering of Super Bioagents for Effective Plant Disease Control

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 11, Page 2821-2855, November 2026.
Genetic engineering (GE) overcomes BCA limits, enabling robust, scalable crop protection. “Super Bioagents” (SBs) use optimized SSs to enhance bioactive molecule delivery. Optimizing SSs enhance precise, sustainable effector deployment for stable disease suppression. SBs use microbiome‐informed design for scalable, next‐gen sustainable crop protection.
Michael Dare Asemoloye
wiley   +1 more source

Virulence factors of Bordetella pertussis [PDF]

open access: yes, 2012
Bordetella pertusis is a Gram-negative, aerobic, non-spore-forming coccobacillus. Although it's strictly human pathogen, it's possible to infect other mammals at laboratory conditions.
Držmíšek, Jakub
core  

Bordetella pertussis pertactin knock-out strains reveal immunomodulatory properties of this virulence factor [PDF]

open access: yesEmerging Microbes & Infections, 2018
Whooping cough, caused by Bordetella pertussis, has resurged and presents a global health burden worldwide. B. pertussis strains unable to produce the acellular pertussis vaccine component pertactin (Prn), have been emerging and in some countries represent up to 95% of recent clinical isolates.
Hovingh, ES   +9 more
openaire   +4 more sources

Bordetella PlrSR regulatory system controls BvgAS activity and virulence in the lower respiratory tract

open access: yes, 2017
Significance Bordetella spp. includes Bordetella pertussis , the causal agent of whooping cough. The Bordetella virulence gene (BvgAS) two-component regulatory system (TCS)
Sara A. Marlatt   +9 more
core   +1 more source

Parasite variation and the evolution of virulence in a Daphnia-microparasite system [PDF]

open access: yes, 2008
Understanding genetic relationships amongst the life-history traits of parasites is crucial for testing hypotheses on the evolution of virulence. This study therefore examined variation between parasite isolates (the bacterium Pasteuria ramosa) from the ...
Little, T. J., Chadwick, W., Watt, K.
core   +1 more source

BopN is a Gatekeeper of the Bordetella Type III Secretion System

open access: yesMicrobiology Spectrum, 2023
The classical Bordetella species infect the respiratory tract of mammals. While B. bronchiseptica causes rather chronic respiratory infections in a variety of mammals, the human-adapted species B. pertussis and B.
Kevin Munoz Navarrete   +6 more
doaj   +1 more source

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